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In8Bio, Inc. (INAB) is a clinical-stage biopharmaceutical leader developing gamma-delta T cell immunotherapies for cancer treatment. This page provides investors and researchers with essential updates on clinical trials, regulatory developments, and strategic partnerships driving innovation in cellular therapies.
Access real-time announcements about the company's DeltEx platform advancements, chemotherapy-resistant cell therapies, and progress across solid tumor and hematologic malignancy programs. Our curated news collection includes earnings reports, trial data publications, and collaborative research milestones.
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IN8bio, Inc. (Nasdaq: INAB) announced promising progress in its Phase 1 trial of INB-100 for high-risk relapsed acute myeloid leukemia (AML) patients. All three patients treated remain alive and disease-free for more than one year post-transplant, with two patients exceeding two years in complete remission. The therapy shows a manageable safety profile, with no severe adverse effects or dose-limiting toxicities reported. The data suggests potential for improved cure rates in AML without significant added risks, with further patient data expected later in 2022.
IN8bio, Inc. (Nasdaq: INAB) announced the issuance of a new European patent covering its Drug Resistant Immunotherapy (DRI) platform, expanding its intellectual property to include NK cells alongside gamma-delta T cells. This patent enhances IN8bio’s position in developing cellular therapies for solid tumors, emphasizing its innovative approach to combat cancer through genetically engineered immune cells. The company is actively advancing its pipeline, including ongoing Phase 1 trials for INB-200 and INB-100, aimed at treating glioblastoma and leukemia, respectively.
IN8bio, Inc. (Nasdaq: INAB) announced the appointment of Kenneth R. LaMontagne, Ph.D., as Senior Vice President of Business Development, aiming to enhance partnership strategies for gamma-delta T cell therapies. Dr. LaMontagne brings over 20 years of experience in cell therapies and oncology, with a history of significant transaction execution in his past roles at Artisan Bio and Bristol Myers Squibb. CEO William Ho emphasized the strategic importance of this leadership addition to increase shareholder value and advance the company's comprehensive pipeline in clinical development.
IN8bio (Nasdaq: INAB) has announced its participation in key conferences this July, focusing on its innovative gamma-delta T cell therapies. The company will present at the Oppenheimer Summit on July 20, with CFO Patrick McCall and CMO Dr. Trishna Goswami available for 1x1 partnering. Additionally, at the 3rd Annual Gamma-Delta T Cell Therapies Summit in Boston (July 26-28), CSO Lawrence Lamb will lead discussions and presentations on maximizing therapeutic outcomes. Lastly, CEO William Ho will deliver a keynote at the GEN Cell & Gene Therapy Summit on July 27.
IN8bio, Inc. (Nasdaq: INAB), a clinical-stage biopharmaceutical company, announced that CEO William Ho will present at the Jefferies Global Healthcare Conference on June 8, 2022, from 1:30 to 1:55 p.m. EDT. The presentation will focus on the company's innovative gamma-delta T cell therapies and its DeltEx platform. Additional upcoming presentations include the Biotechnology Innovation Organization International Convention and the Next Generation CAR & T Cell Therapies event. IN8bio is conducting Phase 1 clinical trials for INB-200 and INB-100, targeting glioblastoma and leukemia.
IN8bio, Inc. (Nasdaq: INAB) reported promising results from its Phase 1 trial for INB-200 in glioblastoma multiforme (GBM) patients. Notably, 100% of patients exceeded the median progression-free survival (PFS), with some exceeding overall survival (OS) expectations. One patient remains stable after one year post-enrollment. The safety profile was manageable with no severe adverse events reported. Enrollment for the third cohort has begun, with further updates anticipated later in 2022.
IN8bio announced the expansion of its DeltEx gamma-delta T cell platform to include induced pluripotent stem cells (iPSCs) at the ASGCT 25th Annual Meeting. Data revealed that iPSC-derived gamma-delta T cells exhibit robust cytotoxicity and can be genetically modified with an internal CAR-T construct, marking a significant advancement in the field. IN8bio is the first to demonstrate directed differentiation of both Vdelta1 and Vdelta2 sub-types. The company plans to host a webcast on May 17, 2022, to discuss these findings and its ongoing clinical programs.
IN8bio, Inc. (Nasdaq: INAB) reported encouraging results for its Phase 1 clinical trials of INB-100 and INB-200, focusing on leukemia and glioblastoma patients. At the EBMT Annual Meeting, all three INB-100 patients were in complete remission, with durable remissions between 9 to 23 months. INB-200 showed a manageable safety profile with no dose-limiting toxicities. Financially, cash decreased to $32.1 million, and R&D expenses rose to $2.4 million. The company experienced a net loss of $6.1 million for Q1 2022, compared to a loss of $3.1 million in Q1 2021.
IN8bio, Inc. (Nasdaq: INAB) announced the launch of its new iPSC-based gamma-delta T cell platform, making it one of the few companies able to create both Vdelta1 and Vdelta2 T cell subtypes. This platform aims to facilitate the scaled manufacturing of 'off-the-shelf' cellular therapies. CEO William Ho highlighted this as a significant advancement, with plans to present data at the ASGCT Annual Meeting from May 16-19, 2022. The company is also set to discuss ongoing clinical trials and its product pipeline during a workshop on May 17, 2022.
IN8bio, Inc. (Nasdaq: INAB), a clinical-stage biopharmaceutical firm, announced its participation in several conferences in May 2022. Highlights include presentations at the ISCT International Society for Cell & Gene Therapy and the Allogeneic Cell Therapies Summit, featuring topics on innovative gamma-delta T cell therapies. Key speakers include CEO William Ho and COO Kate Rochlin. The company also focuses on the DeltEx platform for developing gamma-delta T cell therapies targeting solid tumors and leukemia. IN8bio is conducting Phase 1 trials for products INB-200 and INB-100.