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In8Bio, Inc. (INAB) is a clinical-stage biopharmaceutical leader developing gamma-delta T cell immunotherapies for cancer treatment. This page provides investors and researchers with essential updates on clinical trials, regulatory developments, and strategic partnerships driving innovation in cellular therapies.
Access real-time announcements about the company's DeltEx platform advancements, chemotherapy-resistant cell therapies, and progress across solid tumor and hematologic malignancy programs. Our curated news collection includes earnings reports, trial data publications, and collaborative research milestones.
Key updates cover FDA designations, preclinical study results, and technology licensing agreements. All content is verified for accuracy and relevance to support informed decision-making in the oncology investment space.
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IN8bio, Inc. has appointed Trishna Goswami, M.D. as Chief Medical Officer, effective immediately. Dr. Goswami brings over a decade of experience in immuno-oncology drug development, having worked with notable companies such as Gilead and AstraZeneca. Her expertise includes clinical development for both solid and hematologic tumors, making her a significant addition to IN8bio's leadership team. The company focuses on advancing gamma-delta T cell therapies using its DeltEx platform to improve cancer treatment outcomes. This appointment aligns with IN8bio's goal of progressing multiple therapeutic candidates through clinical development.
IN8bio (Nasdaq: INAB) announced a poster presentation at the 36th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) on November 13, 2021. Dr. Kate Rochlin will present preclinical data on the potential of DeltEx drug-resistant immunotherapy gamma-delta T cells combined with PARP inhibitors to enhance tumor immunogenicity. Notably, temozolomide and niraparib resulted in up to a 29-fold increase in NKG2DL expression in resistant glioblastoma cell lines. This indicates the potential of orthogonal therapies to improve clinical efficacy against solid tumors.
IN8bio, Inc. (Nasdaq: INAB) raised $32.3 million in net proceeds from its IPO, enhancing its capital for clinical programs. The company completed patient dosing of INB-100 in a Phase 1 trial for leukemia while also publishing preclinical data on INB-200 in Scientific Reports. Financial results for Q3 2021 show a cash position of $40.7 million, with R&D expenses rising to $1.4 million. Net loss for the quarter was $3.4 million, compared to $1.7 million in Q3 2020. IN8bio continues to expect initial trial results in 2022 and topline results for all cohorts in 2023.
IN8bio, Inc. (Nasdaq: INAB), a clinical-stage biopharmaceutical company, announced its participation in three scientific conferences this November. Presentations will cover gammas-delta T-cell therapies aimed at treating various cancers. Key events include the Protein & Antibody Engineering Summit on November 4, the SITC Annual Meeting on November 13, and the Society for Neuro-Oncology meeting on November 19. Presenters include top executives and scientists from IN8bio, showcasing innovative cancer treatment approaches using the DeltEx platform.
IN8bio announced significant survival benefits from concurrent dosing of MGMT-modified gamma-delta T cells with Temozolomide (TMZ) in high-grade glioma models. The findings, published in Scientific Reports, support the clinical development of the company’s Drug Resistant Immunotherapy (DRI) technology. Currently, a Phase 1 trial is evaluating DRI with TMZ in glioblastoma multiforme at the University of Alabama at Birmingham. This approach aims to enhance tumor response while maintaining immune functionality.
IN8bio, a clinical-stage biopharmaceutical company, announced that CEO William Ho will present at BioFuture 2021 on October 5 at 10:30 a.m. EDT and participate in a panel on oncology at 1:30 p.m. EDT. Additionally, Kate Rochlin, VP of Operations, will present on gamma-delta T-cell programs at the Advanced Therapies Congress & Expo 2021 the same day at 11:30 a.m. EDT. IN8bio focuses on innovative therapies for tumors using its DeltEx platform, with two Phase 1 trials ongoing for gamma-delta T-cell products targeting glioblastoma and leukemia.
IN8bio, Inc. announced operational and financial highlights for Q2 2021, reporting significant progress in its Phase 1 clinical trials for INB-200 and INB-100. The successful completion of the first cohort treatment in both trials demonstrates strong potential in solid tumors and leukemia. Following a $40M IPO in August 2021, the company bolstered its cash position to $32.6M. However, IN8bio recorded a net loss of $3.1M for the quarter, with R&D expenses rising to $2.1M, indicating ongoing investment in its clinical programs.
IN8bio, a clinical-stage biopharmaceutical company, announced that CEO William Ho will present at two virtual events: NewYorkBIO Virtual Breakfast Series on August 31 at 9 am EDT, and H.C. Wainwright’s 23rd Annual Global Investment Conference from September 13-14. The presentations will highlight the company's innovative gamma-delta T-cell therapies using its DeltEx platform. The H.C. Wainwright presentation will be available for 90 days post-release. IN8bio is currently conducting Phase 1 clinical trials for its lead product candidates targeting glioblastoma and leukemia.
IN8bio has completed dosing for the first cohort in a Phase 1 clinical trial of INB-100, a gamma-delta T-cell therapy for leukemia patients undergoing haploidentical stem cell transplant. No severe adverse infusion reactions or dose limiting toxicities were reported among the three patients. The first two patients remain in complete remission over one year post-dosing. The trial aims to evaluate safety, tolerability, and overall survival, with topline data expected in 2023. IN8bio focuses on innovative T-cell therapies to improve treatment outcomes for leukemia and other cancers.
IN8bio (Nasdaq: INAB) has appointed Emily Fairbairn and Luba Greenwood to its Board of Directors. Both appointees bring extensive experience in the biopharmaceutical and life sciences sectors. Fairbairn, an influential investor and former CEO of Ascend Capital, focuses on corporate governance, while Greenwood's background includes leadership roles at Google Life Sciences and Roche. Their terms will end at the 2022 annual stockholders' meeting. IN8bio aims to advance its clinical-stage gamma-delta T-cell therapies for cancer treatment, utilizing its innovative DeltEx platform.