Welcome to our dedicated page for Inmune Bio news (Ticker: INMB), a resource for investors and traders seeking the latest updates and insights on Inmune Bio stock.
INmune Bio Inc. (NASDAQ: INMB) is a clinical-stage biotechnology company that regularly issues news and updates about its inflammation and immunology pipeline targeting the innate immune system. This news page aggregates company press releases and third-party coverage related to INmune Bio’s DN-TNF platform, CORDStrom™ mesenchymal stromal cell platform, and INKmune® natural killer cell priming platform.
Readers can find updates on XPro™ (XPro1595, pegipanermin), a selective soluble TNF neutralizer that the company is developing for neurological diseases driven by chronic inflammation. Recent news has highlighted Phase 2 MINDFuL trial results in early Alzheimer’s disease with inflammatory biomarkers, neuroimaging analyses using advanced MRI techniques, and manuscript submissions to peer-reviewed journals. The company also reports on scientific presentations at conferences such as the Clinical Trials on Alzheimer’s Disease (CTAD) meeting and the Alzheimer’s Association International Conference.
News related to the CORDStrom™ cell therapy platform includes clinical and manufacturing milestones in recessive dystrophic epidermolysis bullosa (RDEB), such as completion of a blinded randomized trial, pilot-scale commercial manufacturing runs at a cell and gene therapy manufacturing center in the United Kingdom, and intellectual property developments. INmune Bio also issues updates on participation in industry events and panels focused on dermatologic rare diseases and cell therapy manufacturing.
For the INKmune® platform, news items cover progress in the CaRe PC Phase I/II trial in metastatic castration-resistant prostate cancer, including reports that the trial met its primary and certain secondary endpoints, safety observations, and biomarker findings related to NK cell activation. Corporate news, including financing transactions, management changes, and special stockholder meetings, is also disclosed through regular press releases and corresponding SEC filings. Investors and researchers can use this page to follow INMB news on clinical data, regulatory plans, manufacturing scale-up, and corporate developments.
Boca Raton, FL, April 25, 2022 – INmune Bio (NASDAQ: INMB) announced participation in the B. Riley Neuro & Ophthalmology Conference on April 28, 2022. RJ Tesi, MD, President and CEO, will engage in a fireside chat at 11:00 am ET. This invitation-only event caters to B. Riley Securities' institutional clients. INmune Bio is focused on using the innate immune system to develop treatments for diseases such as cancer and Alzheimer's, with products like INB03™ and XPro™ in clinical trials.
INmune Bio (NASDAQ: INMB) has initiated patient enrollment for a crucial six-month Phase 2 trial assessing XPro1595 in patients with mild Alzheimer's disease (AD). This multicenter, randomized, placebo-controlled study aims to evaluate cognitive function and improvement in biomarkers associated with neuroinflammation. Following positive results from the Phase 1 trial, which showed a reduction in neuroinflammation and improvements in neurorepair biomarkers, the company anticipates enrolling 201 patients across the U.S., Australia, and Canada.
INmune Bio (NASDAQ: INMB) has announced significant findings regarding its product INB03 for treating trastuzumab-resistant MUC4 HER2+ breast cancer. Data from animal models indicate that INB03 effectively decreases MUC4 expression, reversing resistance to trastuzumab and tyrosine kinase inhibitors while enhancing an active tumor microenvironment. This research was presented at the American Association of Cancer Research Annual Meeting. Previous studies reveal MUC4 expression correlates with poorer survival outcomes. INB03 is poised for further clinical testing.
INmune Bio (NASDAQ: INMB) presented significant findings regarding its NK cell therapy, INKmune™, during the NK Cells in Solid Tumors workshop at the Innate Killer Summit. Dr. Mark Lowdell, the CSO, emphasized INKmune™'s unique ability to enhance NK cell survival and function in hostile tumor environments by upregulating mitochondrial proteins and nutrient receptors. Clinical data suggests that INKmune-primed NK cells can persist in the body for over 15 weeks, raising the potential for synergistic use with adoptive NK therapies. The company continues to explore collaborations for future clinical trials.
INmune Bio, Inc. (NASDAQ: INMB) announces that its Chief Scientific Officer, Dr. Lowdell, will lead a workshop at the 7th Innate Killer Summit in San Diego from March 30 to April 1, focusing on natural killer (NK) cells in treating solid tumors. The workshop aims to address challenges faced in NK cell therapies. Additionally, INmune will present case studies on INKmune™ showing promising results in three patients, including no side effects and improved disease outcomes. The company continues to advance its clinical trials targeting the innate immune system.
INmune Bio, Inc. (NASDAQ: INMB) recently presented at the AD/PD™ 2022 International Conference on Alzheimer's and Parkinson's diseases held from March 15-20 in Barcelona, Spain. The company emphasized the growing importance of targeting neuroinflammation in Alzheimer's Disease (AD) treatments, particularly with its Xpro™ therapy. Notable findings include improved synaptic function indicators post-treatment and the use of white matter pathology as a biomarker for predicting AD progression. CEO R.J. Tesi highlighted the significance of these insights in advancing clinical trials and drug development strategies.
INmune Bio (NASDAQ: INMB) presented nine data pieces at the AD/PD™ 2022 International Conference, held from March 15-20 in Barcelona, focusing on XPro™'s potential in treating Alzheimer’s Disease. This marks the first exposure for many EU and UK clinicians to INmune Bio’s approach targeting neuroinflammation. Key presentations include MRI measures from the Phase 1 trial and insights for Phase 2 trial design. The data emphasizes XPro™’s versatility and novel biomarkers being utilized in clinical strategies.
INmune Bio (NASDAQ: INMB), a clinical-stage immunology company, announced that its CEO, RJ Tesi, MD, will present at the 32nd Annual Oppenheimer Healthcare Conference from March 15-17, 2022. Dr. Tesi's corporate overview is scheduled for March 16, 2022, at 11:20am ET. Additionally, he will join a fireside chat at the 2022 Maxim Group Virtual Growth Conference on March 30, 2022, at 11:00am ET. INmune Bio is focused on treatments leveraging the immune system to combat diseases like cancer and Alzheimer's. Visit www.inmunebio.com for more information.
INmune Bio, Inc. (NASDAQ: INMB) announced positive results from ongoing clinical trials, including a Phase I trial using INKmuneTM for high-risk myelodysplastic syndrome (MDS) that showed a 60% activation rate of NK cells in a patient after therapy. The company also opened a Phase II trial for treating mild Alzheimer's disease (AD) with XProTM, expecting data in 2023. Financially, INMB reported a net loss of $30.3 million for 2021 but had cash reserves of approximately $74.8 million as of December 31, 2021. Upcoming milestones include expansion of clinical trial sites and additional patient enrollments.
INmune Bio (NASDAQ: INMB) will host a conference call on March 3, 2022, at 4:30 PM ET, to discuss its fourth-quarter results for 2021 and provide a corporate update. The call can be accessed via phone or through a live audio webcast. Participants are encouraged to join several minutes early. A transcript and a replay will be available shortly after the call. INmune Bio is focused on developing therapies that leverage the innate immune system to tackle diseases, with ongoing clinical trials involving products like INB03 and XPro.