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Kane Biotech Presents revyve® Clinical Data at Symposium on Advanced Wound Care (SAWC) Spring Conference

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Kane Biotech (OTC:KNBIF) presented case-study clinical data for revyve at the SAWC Spring conference (April 8-12, 2026).

Highlights include >20-year venous leg ulcers reduced 85% at 33 weeks, complete pain elimination by week 6, 90% wound volume reduction in seven months for a tunneling wound, and wound pH falling from 8.0 to 6.8 in four weeks.

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Positive

  • 85% wound size reduction at 33 weeks in a >20-year venous leg ulcer case
  • Complete pain elimination by week 6 for the long-standing VLU patient
  • 90% wound volume reduction in seven months for a deep tunneling wound
  • pH normalization from 8.0 to 6.8 in four weeks with associated size reductions

Negative

  • Findings presented are case studies and small patient samples, limiting broad generalizability
  • No randomized controlled trial outcomes or large cohort data were reported at SAWC
  • >20 year‑old venous leg ulcers show dramatic healing and pain elimination with revyve
  • Thermoreversible revyve transforms deep tunneling wound care, delivering 90% wound volume reduction
  • revyve rapidly normalizes chronic wound pH, driving accelerated healing in weeks

WINNIPEG, Manitoba, April 16, 2026 (GLOBE NEWSWIRE) -- Kane Biotech Inc. (TSX-V:KNE) (“Kane Biotech”, “Kane” or the “Company”) today announces that Dr. Miloslav Sailer, External R&D Leader, presented at the Symposium on Advanced Wound Care (“SAWC”) Spring conference held from April 8-12, 2026 in Charlotte, North Carolina.

      Thermoreversibility of US FDA 510(k) cleared revyve Antimicrobial Wound Gel and revyve Antimicrobial Wound Gel Spray             

At this year’s conference, Kane Biotech shared case study data on how revyve can help patients with complex chronic non-healing as well as clinical mechanistic investigations. The link to the presentations can be found here and include:

  • A Patient with >20-year-old Venous Leg Ulcers (VLUs) with venous insufficiency, chronic phlebolymphedema, extreme pain, and a combined wound size of >120 cm2 was converted to revyve treatment. After 11 weeks the wound size was reduced by 40% with complete elimination of pain by week 6. Follow-up at 33 weeks demonstrated 85% wound size reduction.
  • A quadriplegic patient with a 1.5-year-old deep tunneling wound switched from packing the wound with impregnated gauze, to filling the contours of the cavity using the thermoreversible technology of revyve. The patient converted to a healing trajectory with significant pain reduction and 90% wound volume reduction in 7 months.
  • Mechanistic investigations of revyve showed the chronic wound average pH dropped from a pH 8.0 to a pH 6.8 in 4 weeks with an associated 45% average wound size reduction in 4 weeks for two patients and a 60% wound size reduction in 1 week with a third patient.

SAWC is a multidisciplinary community of wound care professionals — including physicians, nurses, podiatrists, physical therapists, researchers, administrators and wound care companies — that share the latest evidence-based practices, clinical innovations, and research aimed at improving outcomes in wound management.

About Kane Biotech Inc. (TSX-V:KNE)
Kane Biotech is commercializing and developing novel wound care treatments that disrupt biofilms and transform healing outcomes. Biofilms are one of the main contributors to antibiotic resistance in wounds, resulting in serious clinical outcomes and significant cost. revyve addresses both biofilms and wound bacteria. revyve Antimicrobial Wound Gel, revyve Antimicrobial Wound Gel Spray and revyve Antimicrobial Skin and Wound Cleanser are all U.S. FDA 510(k) cleared. revyve Antimicrobial Wound Gel and revyve Antimicrobial Wound Gel Spray are also Health Canada approved. To learn more, visit revyvegel.com or revyvegel.ca.

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Website: kanebiotech.com

LinkedIn: https://www.linkedin.com/company/kanebiotech/

Presentation: Disrupting Biofilms to Save Limbs and Transform Wound Care

For more information:

Dr. Robert HuizingaRay Dupuis
Interim CEOChief Financial Officer
Kane Biotech Inc.Kane Biotech Inc.
rhuizinga@kanebiotech.comrdupuis@kanebiotech.com
(780) 970-1100(204) 298-2200
  

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Caution Regarding Forward-Looking Information
This press release contains certain statements regarding Kane Biotech Inc. that constitute forward-looking information under applicable securities law. These statements reflect management’s current beliefs and are based on information currently available to management. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied in such statements. These risks and uncertainties include, but are not limited to, risks relating to the Company’s: (a) financial condition, including lack of significant revenues to date and reliance on equity and other financing; (b) business, including its early stage of development, government regulation, market acceptance for its products, rapid technological change and dependence on key personnel; (c) intellectual property including the ability of the Company to protect its intellectual property and dependence on its strategic partners; and (d) capital structure, including its lack of dividends on its common shares, volatility of the market price of its common shares and public company costs. Further information about these and other risks and uncertainties can be found in the disclosure documents filed by the Company with applicable securities regulatory authorities, available at www.sedarplus.ca. The Company cautions that the foregoing list of factors that may affect future results is not exhaustive.

An image accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/a7606fbc-273a-4100-a03b-cc73a0d8cd61


FAQ

What clinical results did Kane Biotech (KNBIF) present for revyve at SAWC April 2026?

They reported significant healing in case studies, including an 85% wound size reduction at 33 weeks and pain elimination by week 6. According to Kane Biotech, other cases showed 90% wound volume reduction in seven months and rapid pH normalization.

How quickly did revyve change wound pH in the SAWC mechanistic data for KNBIF?

revyve lowered chronic wound pH from 8.0 to 6.8 in four weeks in the presented cases. According to Kane Biotech, this pH shift accompanied a 45% average wound size reduction in the same four-week period.

What was the outcome for the >20-year venous leg ulcers case presented by Kane Biotech (KNBIF)?

The >20-year venous leg ulcers case showed a 40% size reduction at 11 weeks and 85% reduction at 33 weeks with pain eliminated by week 6. According to Kane Biotech, the patient moved to revyve treatment and improved steadily.

What improvement did the quadriplegic patient experience with revyve in Kane Biotech's SAWC presentation?

The quadriplegic patient with a 1.5-year deep tunneling wound achieved a healing trajectory and 90% wound volume reduction in seven months. According to Kane Biotech, pain was significantly reduced after switching to revyve thermoreversible filling.

Are Kane Biotech's (KNBIF) SAWC results from large trials or case studies?

The SAWC presentation reported case-study and mechanistic data rather than large randomized trials. According to Kane Biotech, the findings derive from individual patient cases and small cohorts presented at the conference.