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Kymera Therapeutics Announces Late-Breaking Oral Presentation of KT-621 Phase 1b Data at the American Academy of Dermatology (AAD) Annual Meeting

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Kymera Therapeutics (NASDAQ: KYMR) announced that data from its KT-621 BroADen Phase 1b trial in moderate-to-severe atopic dermatitis will be presented as a late-breaking oral presentation at the American Academy of Dermatology (AAD) 2026 Annual Meeting.

The oral session is scheduled for March 28, 2026 at 9:24 AM MT in Bellco Theatre, Denver. Kymera will also host a booth (#3551) in the exhibit hall. A copy of the presentation will be posted in Kymera's Resource Library after the session.

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News Market Reaction – KYMR

-0.54%
-0.54% Session close to close

In the Mar 10 session, KYMR declined 0.54%, reflecting a mild negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights that KT-621 Phase 1b data in atopic dermatitis will be featured as a la...
Analysis

This announcement highlights that KT-621 Phase 1b data in atopic dermatitis will be featured as a late-breaking oral presentation at AAD 2026 on March 28, 2026. It adds to a series of recent milestones, including positive Phase 1b data and advancing Phase 2b trials. Investors may watch for detailed efficacy and safety results, how they relate to ongoing Phase 2b programs, and any updates to development timelines or regulatory strategy.

Key Figures

Trial phase: Phase 1b AAD 2026 dates: March 27–31, 2026 Presentation date: March 28, 2026 +2 more
5 metrics
Trial phase Phase 1b KT-621 BroADen atopic dermatitis trial
AAD 2026 dates March 27–31, 2026 American Academy of Dermatology Annual Meeting
Presentation date March 28, 2026 Late-breaking oral session for KT-621
Presentation time 9:24 AM MT KT-621 Phase 1b oral presentation slot
Exhibit booth #3551 Kymera booth at AAD 2026 exhibit hall

Historical Context

5 past events · Latest: Feb 26 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Feb 26 Earnings and update Positive +4.8% Q4/full-year 2025 results, KT-621 data, Fast Track, strong cash balance.
Feb 24 Investor conferences Positive +2.9% Participation in multiple March investor conferences and webcasts.
Feb 19 Earnings date set Neutral +1.6% Announcement of upcoming Q4/full-year 2025 earnings call and webcast.
Feb 04 Investor conferences Positive +0.6% February investor conference participation and webcast availability.
Jan 29 Clinical trial start Positive +3.9% First patient dosed in BREADTH Phase 2b asthma trial of KT-621.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news, including earnings, clinical, and conference updates, has generally been followed by positive price reactions, suggesting constructive sentiment around the KT-621 program and corporate updates.

Recent Company History

Over the last several months, Kymera has reported multiple milestones tied to KT-621 and corporate visibility. On Jan 29, 2026, first-patient dosing in the BREADTH Phase 2b asthma trial saw a 3.86% gain. Subsequent investor conference announcements in early February also coincided with positive moves. The Feb 26, 2026 Q4/full-year 2025 results, highlighting $1.6 billion in cash and positive KT-621 Phase 1b data, were followed by a 4.8% rise. Today’s AAD late-breaking oral presentation fits this trajectory of growing clinical and scientific visibility.

Key Terms

phase 1b, atopic dermatitis, oral stat6 degrader
3 terms
phase 1b medical
"KT-621 BroADen Phase 1b clinical trial in patients with atopic dermatitis"
"Phase 1b" is an early stage in testing a new medical treatment or vaccine, where it is given to a small group of people to evaluate its safety and determine the right dose. For investors, this phase signals progress in development, indicating the treatment is advancing through initial safety checks, which can influence expectations for future success and potential market impact.
atopic dermatitis medical
"Phase 1b clinical trial in patients with atopic dermatitis will be presented"
A chronic inflammatory skin condition, often called eczema, that causes dry, itchy, red patches and recurring flare-ups; think of it as a persistent rash that can come and go over a person’s life. It matters to investors because its chronic nature and large patient population create steady demand for treatments, influence drug development and approval decisions, affect healthcare costs and reimbursement, and can drive revenue and valuation shifts for companies working on therapies and diagnostics.
oral stat6 degrader medical
"Clinical Activity and Safety of KT-621, an Oral STAT6 Degrader, in Moderate-to-Severe"
An oral STAT6 degrader is a pill-form drug designed to make cells remove STAT6, a protein that helps turn on genes driving allergic inflammation and certain disease processes; instead of merely blocking the protein’s action, the drug tags it for destruction so the cell disposes of it. For investors this matters because degrading a disease-driving protein can produce stronger or longer-lasting effects than traditional blockers, affecting clinical success, regulatory risk, and potential market value much like replacing a broken part rather than temporarily covering it.

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WATERTOWN, Mass., March 10, 2026 (GLOBE NEWSWIRE) -- Kymera Therapeutics, Inc. (NASDAQ: KYMR), a clinical-stage biopharmaceutical company advancing a new class of oral small molecule degrader medicines for immunological diseases, today announced that data from its KT-621 BroADen Phase 1b clinical trial in patients with atopic dermatitis will be presented in a late-breaking oral session at the American Academy of Dermatology (AAD) 2026 Annual Meeting. The meeting will be held March 27-31, 2026, in Denver, CO. Kymera will also host a booth (#3551) in the congress exhibit hall.

“We are honored to have our KT-621 BroADen Phase 1b data selected for a late-breaking oral presentation at AAD,” said Jared Gollob, MD, Chief Medical Officer, Kymera Therapeutics. “We look forward to engaging with the dermatology community at this important forum and sharing our work to develop novel oral medicines for patients living with chronic immuno-inflammatory diseases.”

AAD 2026 Late-Breaking Presentation Details

  • Abstract Title: Clinical Activity and Safety of KT-621, an Oral STAT6 Degrader, in Moderate-to-Severe Atopic Dermatitis: Phase 1b Trial Results
  • Session Title: Late-Breaking Research: Session 1
  • Session Type: Oral Presentation
  • Presentation Date/Time: Saturday, March 28, 2026, 9:24 AM MT
  • Location: Bellco Theatre

A copy of the presentation will be available in the Resource Library section of Kymera's website after the session.

About KT-621
KT-621 is an investigational, first-in-class, once-daily oral degrader of STAT6, the specific transcription factor responsible for IL-4/IL-13 signaling and the central driver of Type 2 inflammation. KT-621 is currently being evaluated in parallel Phase 2b clinical trials in atopic dermatitis (BROADEN2) and asthma (BREADTH). By selectively targeting STAT6 for degradation, KT-621 has the potential to provide a novel oral approach for patients living with Type 2 inflammatory diseases, which affect more than 140 million people worldwide.

About Kymera Therapeutics
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X or LinkedIn.

Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, implied and express statements about our expectations regarding strategy, business plans and objectives on the development of our clinical and preclinical pipeline, including the therapeutic potential, clinical benefits and safety thereof. The words "may," "might," "will," "could," "would," "should," "expect," "plan," "anticipate," "intend," "believe," "expect," "estimate," "seek," "predict," "future," "project," "potential," "continue," "target," “upcoming” and similar words or expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from any forward-looking statements contained in this press release, including, without limitation, risks associated with: that preclinical and clinical data, including the results from the Phase 1 trials of KT-621, are not predictive of, may be inconsistent with, or more favorable than, data generated from future or ongoing clinical trials of the same product candidate, uncertainties inherent in the initiation, timing and design of future clinical trials, the availability and timing of data from ongoing and future clinical trials and the results of such trials, the ability to successfully demonstrate the safety and efficacy of drug candidates, the unexpected emergence of adverse events or other undesirable side effects during preclinical and clinical development, and other factors. These risks and uncertainties are described in greater detail in the section entitled "Risk Factors" in the most recent Quarterly Report on Form 10-Q and in subsequent filings with the SEC. In addition, any forward-looking statements represent our views only as of today and should not be relied upon as representing our views as of any subsequent date. We explicitly disclaim any obligation to update any forward-looking statements. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

Investor Contact: 
Justine Koenigsberg
Vice President, Investor Relations
investors@kymeratx.com
857-285-5300 

Media Contact:
Matthew Henson
Vice President, Corporate Communications
mhenson@kymeratx.com
857-285-5300


FAQ

What does Kymera (KYMR) announce about KT-621 at AAD 2026?

Kymera will present late-breaking Phase 1b KT-621 data in an oral session on March 28, 2026. According to Kymera, the presentation covers clinical activity and safety of KT-621, an oral STAT6 degrader, in moderate-to-severe atopic dermatitis and will be available afterward in its Resource Library.

When and where is Kymera's KT-621 late-breaking oral presentation at AAD 2026?

The presentation is scheduled for March 28, 2026 at 9:24 AM MT in Bellco Theatre A. According to Kymera, the session is part of AAD 2026 late-breaking research and the company will also staff booth #3551 in the exhibit hall during the meeting.

What trial results will Kymera (KYMR) present for KT-621 at AAD?

Kymera will present Phase 1b BroADen trial results on clinical activity and safety of KT-621 in moderate-to-severe atopic dermatitis. According to Kymera, the late-breaking abstract specifically addresses activity and safety of KT-621, described as an oral STAT6 degrader.

Will Kymera (KYMR) make KT-621 presentation materials available after AAD 2026?

Yes. Kymera will post a copy of the presentation in its Resource Library after the session concludes. According to Kymera, attendees and investors can access the presentation materials on the company's website following the March 28, 2026 oral session.

How can investors engage with Kymera (KYMR) during the AAD 2026 meeting?

Investors can attend the late-breaking KT-621 oral session and visit Kymera at booth #3551 in the exhibit hall. According to Kymera, company representatives will be on site to discuss the Phase 1b data and share additional information at the conference.