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Kazia Therapeutics (KZIA): Deep Dive Into Childhood Brain Cancer

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LONDON, UK / ACCESSWIRE / May 26, 2022 / In light of the positive newsflow from Kazia's efforts in addressing adult brain cancer, management is leveraging its niche expertise and experience to address a complex and untapped segment, childhood brain cancer. Due to the challenges in addressing this unmet need, including significant hurdles in enrolling patients for a clinical trial, there is a vacuum of options for those served with this diagnosis. As Kazia is working to pioneer this sub-segment, leveraging its network, in this note we examine the science and attempt to connect the dots on the potential market opportunity and dynamics despite the limited data points to date.

Our NPV valuation of US$294m or US$22.28 per basic ADR remains unchanged. Kazia reported net cash of US$11.0m (A$15.2m) at the end of December (2021), which we estimate will fund the company into H123 (H2 CY22). We expect the company will need to seek roughly US$51m in financing (including US$22m in FY23 and US$22m in FY24). Kazia established a US$35m at-the-market program in April 2022, which may fulfil a portion of our projected funding needs. The company had gross cash of A$6.958m at 31 March and in its 4C quarterly statement management reported a Q322 operating cash burn rate of A$6.5m.

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Kazia Therapeutics Limited

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About KZIA

innovative. focused. agile. kazia therapeutics is an agile, oncology-focused biotechnology company, based in sydney, australia. we have two clinical staged drug development candidates and an early stage discovery program, across a range of oncology indications. our lead program is gdc-0084, a small molecule inhibitor of the pi3k / akt / mtor pathway, which is being developed to treat glioblastoma multiforme, the primary and most aggressive form of brain cancer. licensed from genentech in late 2016, gdc-0084 is anticipated to enter phase ii clinical trials in 2017. trxe-002-1, or cantrixil is kazia’s second drug development candidate under development as a treatment for ovarian cancer. the chemotherapeutic is currently undergoing a phase 1 clinical trial in hospitals across australia and the united states. initial data on this trial is expected to be reported early in 2018. kazia therapeutics is trading under the following tickers: asx: kza nasdaq: kzia for more information, please visi