Welcome to our dedicated page for LAVA Therapeutics N.V. news (Ticker: LVTX), a resource for investors and traders seeking the latest updates and insights on LAVA Therapeutics N.V. stock.
LAVA Therapeutics N.V. (LVTX) news coverage on this page centers on the company’s evolution as a clinical-stage immuno-oncology developer and its corporate transition following an acquisition by XOMA Royalty Corporation. Company press releases and SEC-linked announcements describe how LAVA advanced its proprietary Gammabody® platform of bispecific gamma-delta T cell engagers, while also undertaking restructuring measures and a strategic review that ultimately led to a tender offer and change of control.
Readers can follow updates related to LAVA’s pipeline programs, including the internal candidate LAVA‑1266 for CD123+ hematologic malignancies and partnered Phase 1 programs JNJ‑89853413 with Johnson & Johnson and PF‑08046052 with Pfizer Inc. News items detail clinical trial progress, portfolio reprioritization, and decisions to discontinue earlier programs such as LAVA‑1207 and LAVA‑051. These releases provide insight into how the company focused its resources on select assets while maintaining key collaborations.
Another major theme in LVTX news is corporate and capital structure events. LAVA announced an evaluation of strategic options, workforce reductions, closure of Netherlands operations, and a waiver of an Innovation Credit repayment obligation from the Netherlands Enterprise Agency (RVO). Subsequent news and 8‑K references document the share purchase agreement with XOMA Royalty Corporation, amendments to the offer terms, shareholder approvals at an extraordinary general meeting, and the successful tender of a large majority of outstanding shares.
For investors researching LVTX historically, this news stream provides context on both the scientific direction of LAVA’s Gammabody® platform and the sequence of events that resulted in LAVA becoming a majority-owned subsidiary of XOMA Royalty Corporation and delisting from the Nasdaq Global Select Market. Bookmark this page to access archived announcements, transaction milestones, and program updates associated with the former LVTX listing.
LAVA Therapeutics N.V. (Nasdaq: LVTX) announced the appointment of Christy J. Oliger to its board of directors effective March 9, 2023. Oliger brings over 30 years of experience in the biopharmaceutical industry, including senior leadership roles at Genentech. She is recognized for her expertise in oncology and has led significant product launches. The company also announced the departure of Stefan Luzi, Ph.D., from the board. LAVA focuses on its proprietary Gammabody™ platform for developing bispecific gamma-delta T cell engagers targeting various malignancies, with ongoing clinical studies for its lead candidate LAVA-051.
LAVA Therapeutics announced initial clinical data from its ongoing Phase 1/2a study of LAVA-1207 for treating therapy refractory metastatic castration-resistant prostate cancer (mCRPC). The results, presented at ASCO GU, show a favorable safety profile with no high-grade cytokine release syndrome. Preliminary signs of anti-tumor activity were noted, including stable disease in 8 out of 14 patients and PSA levels stabilizing or decreasing. The trial features a dose escalation up to 120 micrograms, with treatment duration ranging from 4 to 38 weeks.
LAVA Therapeutics N.V. (Nasdaq: LVTX), a clinical-stage immuno-oncology company, announced that its CEO, Stephen Hurly, will present at the 2023 SVB Securities Global Biopharma Conference.
The presentation is scheduled for February 16, 2023, from 1:00 p.m. to 1:30 p.m. EST. A webcast will be available on the company's investor relations page and archived for 90 days post-event.
LAVA focuses on developing its proprietary Gammabody™ platform to create bispecific gamma-delta T cell engagers for cancer treatment, with notable pipeline candidates including LAVA-051 and LAVA-1207.
LAVA Therapeutics N.V. (Nasdaq LVTX) has appointed Dr. Charles Morris as Chief Medical Officer, effective February 6, 2023, succeeding Benjamin Winograd. Dr. Morris brings over 25 years of oncology experience, having held leadership roles at various biotech firms, including Celyad Oncology and Radius Health. His expertise in advancing oncology products is expected to enhance LAVA's Gammabody™ platform, aimed at treating various cancers with bispecific gamma-delta T cell engagers. The company is currently enrolling patients in clinical studies for its lead candidate, LAVA-051, and is optimistic about its potential to transform cancer treatment.
LAVA Therapeutics, a clinical-stage immuno-oncology company, announced that data from its Phase 1/2a study on LAVA-1207 will be presented at the ASCO GU Symposium in San Francisco from February 16-18, 2023. The presentation will focus on the early dose escalation of LAVA-1207, a bispecific gamma-delta T cell engager, in patients with therapy-refractory metastatic castration-resistant prostate cancer (mCRPC). The abstract (153) will be part of Poster Session A on February 16. LAVA aims to transform cancer treatment using its Gammabody™ platform and is also conducting trials with its lead candidate LAVA-051 for various hematologic malignancies.
LAVA Therapeutics announced the appointment of Peter A. Kiener, DPhil, and Mary E. Wadlinger to its Board of Directors, effective January 1, 2023. Kiener brings extensive experience in biologics and immunotherapy, having held leadership roles at multiple biopharmaceutical companies. Wadlinger has a strong background in human resources within the biotech sector. This transition follows Guido Magni's departure from the board, who contributed significantly since 2018. The new appointments aim to advance LAVA's strategy in developing bispecific gamma delta T cell engagers for cancer treatment.
LAVA Therapeutics, a clinical-stage immuno-oncology company, announced that CEO Stephen Hurly will present at the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023. The presentation will take place from 10:30 a.m. to 11:10 a.m. PST. Interested parties can access a webcast of the presentation on the LAVA Therapeutics investor relations website, with a replay available for 90 days. The company focuses on its proprietary Gammabody™ platform, developing bispecific gamma-delta T cell engagers targeting various cancers, including multiple myeloma.
LAVA Therapeutics (Nasdaq: LVTX) announced a poster presentation at the 64th ASH Annual Meeting showcasing initial data from its ongoing Phase 1/2a trial of LAVA-051. The study targets patients with relapsed/refractory chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).
The preliminary results indicate successful dose escalation to 200 µg without significant toxicity or cytokine release syndrome. The therapy demonstrated predictable pharmacokinetics and early signs of clinical activity, with ongoing dose escalations in the US and EU.
LAVA Therapeutics N.V. (Nasdaq: LVTX) announced key developments in its pipeline and financial results for Q3 2022. Notable highlights include the presentation of interim clinical data for LAVA-051 in treating relapsed or refractory chronic lymphocytic leukemia and multiple myeloma at the ASH Annual Meeting. Additionally, LAVA secured a $50 million upfront payment from Seagen for an exclusive worldwide license agreement on LAVA-1223, providing a cash runway beyond 2024. Research and license revenue for Q3 reached $15.3 million, up from $2.1 million in 2021.
LAVA Therapeutics, a clinical-stage immuno-oncology company focused on bispecific gamma delta T cell engagers, announced that CEO Stephen Hurly will present at the Jefferies London Healthcare Conference.
The presentation is scheduled for November 17, 2022, from 8:00 a.m. to 8:30 a.m. GMT (3:00 a.m. to 3:30 a.m. EST). A webcast will be available in the investor relations section of their website and archived for 90 days afterward.