Welcome to our dedicated page for Lyell Immunopharma news (Ticker: LYEL), a resource for investors and traders seeking the latest updates and insights on Lyell Immunopharma stock.
Lyell Immunopharma, Inc. (NYSE: LYEL) is a clinical-stage biotechnology company developing novel T-cell therapies for solid tumors and hematologic malignancies through proprietary genetic/epigenetic reprogramming technologies. This page serves as the definitive source for verified company announcements, research breakthroughs, and regulatory developments.
Investors and researchers will find timely updates on Lyell's innovative pipeline including CAR T-cell candidates LYL797 and LYL119, tumor-infiltrating lymphocyte therapy LYL845, and dual-targeting IMPT-314 from the ImmPACT Bio acquisition. Our curated news collection covers essential developments across three key areas:
Clinical Trial Milestones: Phase 1/2 updates, patient enrollment progress, and safety/efficacy data disclosures
Research Innovations: Peer-reviewed study publications, ASCO/SITC presentations, and new patent filings
Strategic Developments: Manufacturing partnerships, leadership appointments, and regulatory pathway updates
Bookmark this page for direct access to Lyell's official press releases, SEC filings, and scientifically validated progress reports. Check regularly for updates on technologies addressing T-cell exhaustion and improving durable response rates in cancer immunotherapy.
Lyell Immunopharma, Inc. (Nasdaq: LYEL) announced the acceptance of three abstracts for presentation at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC) in Houston, TX, from Nov. 6-10, 2024. The presentations will highlight Lyell's pipeline of clinical product candidates and anti-exhaustion technology for cell therapies targeting solid tumors and hematologic malignancies.
Key presentations include:
- Translational data from the LYL797 Phase 1 clinical trial, demonstrating solid tumor infiltration and cell killing by reprogrammed ROR1 CAR T cells
- Multiomic profiling of LYL119, a reprogrammed ROR1 CAR T product with reduced exhaustion and enhanced memory characteristics
- Utilization of Stim-R™ Technology to reduce irradiated feeder cells in tumor infiltrating lymphocyte culture process
These presentations will provide insights into Lyell's progress in developing innovative cell therapies for cancer treatment.
Lyell Immunopharma (Nasdaq: LYEL), a clinical-stage T-cell reprogramming company, has announced its participation in the Goldman Sachs Cell Therapy Day on October 1. Lynn Seely, MD, Lyell's President & CEO, will be part of a panel discussion focusing on next-generation cell therapies in oncology at 11:50 a.m. ET.
The company, which is advancing a diverse pipeline of cell therapies for patients with solid tumors or hematologic malignancies, will provide a webcast of the presentation through the Investors section of their website at www.lyell.com. A replay of the webcast will be available on the company's website following the presentation date.
Lyell Immunopharma (Nasdaq: LYEL), a clinical-stage T-cell reprogramming company, has announced its participation in two upcoming investor conferences in September 2024. The company's senior management team will present at the Morgan Stanley 22nd Annual Global Healthcare Conference on September 4th at 10:45 am ET and the H.C. Wainwright 26th Annual Global Investment Conference on September 9th at 8:30 am ET.
Lyell Immunopharma specializes in developing cell therapies for patients with solid tumors or hematologic malignancies. Interested parties can access live webcasts of the presentations through the Investors section of Lyell's website. Replays will be available on the company's website following each presentation.
Lyell Immunopharma (NASDAQ: LYEL) reported Q2 2024 results and business highlights:
- LYL797 Phase 1 trial showed 40% objective response rate and 60% clinical benefit rate in triple-negative breast cancer at highest dose
- Expanded LYL797 development into four new tumor types
- FDA cleared IND for LYL119, a next-gen ROR1-targeted CAR T-cell therapy
- $491.1 million in cash and equivalents as of June 30, 2024
- Net loss of $45.8 million for Q2 2024, compared to $63.9 million in Q2 2023
- R&D expenses decreased to $40.3 million from $47.5 million year-over-year
- G&A expenses decreased to $12.3 million from $19.0 million year-over-year
- Cash runway extended into 2027
Lyell Immunopharma has announced initial clinical data from its Phase 1 trial of LYL797, a ROR1-targeted CAR-T cell product enhanced with anti-exhaustion technology. Key findings include a 40% objective response rate (ORR) and a 60% clinical benefit rate (CBR) at the highest dose of 150 million CAR T cells in patients with triple-negative breast cancer (TNBC). The trial demonstrated that LYL797 can proliferate, infiltrate tumors, and kill cancer cells. No dose-limiting toxicities were reported in patients without lung metastases, although treatable pneumonitis was observed in those with lung involvement. Lyell is expanding the trial to include other ROR1+ cancers and has submitted an IND for LYL119, their next-generation product. An investor webcast will be held today at 8:30 am ET.
Lyell Immunopharma, a clinical-stage company specializing in T-cell reprogramming for solid tumor cell therapies, announced participation in the Goldman Sachs 45th Annual Global Healthcare Conference. The event is scheduled for June 10 at 4:00 pm ET. Senior management will present during this conference, and a live webcast will be accessible through Lyell's investor section on www.lyell.com. A replay will also be made available post-presentation.
Lyell Immunopharma, a clinical-stage T-cell reprogramming company, will participate in the BofA Securities Health Care Conference on May 14, 2024. The company will showcase its diverse pipeline of cell therapies for solid tumors. Investors can access the live webcast on the Company's website.
Lyell Immunopharma, Inc. (Nasdaq: LYEL) reported business highlights for Q1 2024, including strong financial position with $526.3 million in cash and ongoing advancement of diverse cell therapy pipeline. Key updates include initial clinical data expected for LYL797 and LYL845, IND submission for LYL119, and promising nonclinical data presented at AACR Annual Meeting 2024.
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