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MBX Biosciences to Host In-Person and Virtual Obesity Day on May 11, 2026 to Discuss Expanding Obesity Portfolio

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MBX Biosciences (Nasdaq: MBX) will host an in-person and virtual Obesity Day on May 11, 2026 at 10:30 a.m. ET to provide an update on its expanding obesity portfolio and Precision Endocrine Peptide™ (PEP™) platform.

Speakers include Richard DiMarchi, Ph.D., and Katherine H. Saunders, M.D., followed by a live Q&A. The live webcast is available in the Events section of the MBX Biosciences investor website and a replay will be archived for ~90 days.

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Positive

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Negative

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News Market Reaction – MBX

-0.57%
12 alerts
-0.57% Session close to close
$1.51B Market Cap
0.4x Rel. Volume

In the Apr 23 session, MBX declined 0.57%, reflecting a mild negative market reaction. Our momentum scanner triggered 12 alerts that day, indicating notable trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement schedules an Obesity Day to highlight MBX’s expanding obesity portfolio and Precis...
Analysis

This announcement schedules an Obesity Day to highlight MBX’s expanding obesity portfolio and Precision Endocrine Peptide platform. It follows recent milestones, including an End-of-Phase 2 FDA meeting and a planned Phase 3 trial for canvuparatide, plus 2025 results showing $459.1M in cash expected to fund operations into 2029. An effective S-3ASR shelf allowing up to $250,000,000 of at‑the‑market common stock sales and insider purchasing activity are key context points investors may monitor alongside future clinical updates.

Key Figures

Pro forma cash & investments: $459.1M 2025 net loss: $87.0M ATM capacity: $250,000,000 +5 more
8 metrics
Pro forma cash & investments $459.1M As of Dec 31, 2025; expected to fund operations into 2029
2025 net loss $87.0M Full-year 2025 net loss
ATM capacity $250,000,000 S-3ASR sales agreement prospectus for common stock with Jefferies LLC
Shares outstanding 47,570,485 Common shares outstanding as of Apr 10, 2026 (DEF 14A)
CEO 2025 total compensation $2,990,867 Salary, bonus, and option awards for CEO P. Kent Hawryluk
Insider purchase 18,500 shares at $28.4142 CEO open‑market purchase on Mar 13, 2026
Phase 3 sample size ~160 patients Planned randomized Phase 3 trial for canvuparatide in hypoparathyroidism
Fixed dose level 600 micrograms Initial 4‑week fixed dose in planned Phase 3 canvuparatide trial

Historical Context

5 past events · Latest: Mar 12 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 12 Earnings and update Positive -3.4% Reported 2025 results, strong cash of $459.1M and development milestones.
Mar 10 Executive hire Positive +3.8% Appointed Chief Business Officer with $10B+ deal experience.
Mar 09 Clinical phase update Positive -8.5% Successful End-of-Phase 2 FDA meeting and Phase 3 plan for canvuparatide.
Mar 09 Clinical phase update Positive -8.5% Detailed Phase 3 design and EMA orphan drug designation for canvuparatide.
Feb 23 Investor conferences Positive +5.6% Announced participation in multiple March investor conferences and webcasts.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Clinically positive or strategic updates have sometimes seen negative or mixed next-day reactions, while corporate and investor-relations news has more often aligned with positive moves.

Recent Company History

Recent MBX news has focused on progressing its endocrine and metabolic pipeline and strengthening its corporate platform. On Mar 9, 2026, it announced a successful End-of-Phase 2 FDA meeting and a planned Phase 3 trial for canvuparatide with EMA orphan designation, yet the stock fell 8.54%. Q4 and 2025 results on Mar 12, 2026 highlighted $459.1M in cash funding operations into 2029, but shares still dipped. By contrast, a new Chief Business Officer and March conference participation in 2026 were followed by positive price reactions.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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CARMEL, Ind. and BURLINGTON, Mass., April 23, 2026 (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced that it will host an in-person and virtual Obesity Day on Monday, May 11, 2026 at 10:30 a.m. ET to provide an update on its expanding obesity portfolio of products. For more details and to register for the event, click here.

The event will feature Richard DiMarchi, Ph.D. (Distinguished Professor of Chemistry, Indiana University; Scientific Co-Founder, MBX Biosciences, Inc.) and Katherine H. Saunders, M.D. (Co-Founder, FlyteHealth; Clinical Assistant Professor of Medicine, Weill Cornell Medicine), who will join company management to discuss the evolving treatment landscape and remaining treatment gaps in obesity.

MBX management will provide an overview of MBX’s Precision Endocrine Peptide™ (PEP™) platform and its application to the development of long-acting peptide therapies for obesity, as well as an update on the Company’s obesity product candidates.

A live Q&A session will follow the formal presentations.

The live webcast can be accessed in the Events section of the MBX Biosciences website at https://investors.mbxbio.com/news-events/events. A replay of the webcast will be archived on the Company’s website for approximately 90 days.

About Richard DiMarchi, Ph.D.

Richard DiMarchi, Ph.D., is a Distinguished Professor of Chemistry at Indiana University and a globally recognized leader in peptide drug design, with prior senior leadership roles at Eli Lilly and Novo Nordisk. He is recognized for his contributions to the discovery and development of Humalog®, rGlucagon®, and Forteo®, and his research has advanced the understanding of glucagon biology and the development of single-molecule multi-agonists for metabolic diseases, including the first GLP-1/GIP co-agonist and GLP-1/GIP/glucagon triple agonist. As Scientific Co-Founder of MBX Biosciences, he has helped pioneer the Company’s PEP™ platform, including its pipeline of novel peptide-based drug candidates. He is a member of the National Academy of Medicine and the National Inventors Hall of Fame and is co-inventor on more than 100 U.S. patents with over 300 scientific publications with an h-index >85.

About Katherine H. Saunders, M.D.

Katherine H. Saunders, M.D., is a physician entrepreneur and internationally recognized expert in obesity medicine, focused on advancing effective, evidence-based care for patients with obesity and associated comorbidities. She is Co-Founder of FlyteHealth, a company dedicated to expanding access to cardio-kidney-metabolic treatment and serves on faculty at Weill Cornell Medicine. Dr. Saunders completed her medical training at Weill Cornell Medical College and NewYork-Presbyterian/Weill Cornell, where she was the first fellow in obesity medicine. She is board-certified in Internal Medicine and Obesity Medicine, has authored more than 50 peer-reviewed publications, and is a frequent speaker and media contributor on the evolving obesity treatment landscape.

About MBX Biosciences

MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP™ platform, for the treatment of endocrine and metabolic disorders. The company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The company’s pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism (HP) preparing for Phase 3 development; an obesity portfolio that includes MBX 4291 in Phase 1 development, as well as multiple discovery and pre-clinical obesity candidates; and imapextide (MBX 1416) for the treatment of post-bariatric hypoglycemia (PBH) in Phase 2 development. The company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the company website at www.mbxbio.com and follow it on LinkedIn.

Media Contact:

George Shea
We. Communications
gshea@wecommunications.com
(937) 232-4889

Investor Contact:

Jim DeNike
MBX Biosciences
jdenike@mbxbio.com


FAQ

When is MBX Biosciences' Obesity Day and how can I attend the May 11, 2026 event?

The event is on May 11, 2026 at 10:30 a.m. ET; attendance is available in person or virtually. According to MBX Biosciences, registration details and the live webcast link are provided on the company’s Events page for investors.

What topics will MBX Biosciences cover during the May 11, 2026 Obesity Day webcast?

MBX will overview its PEP™ platform, long-acting peptide therapies for obesity, and obesity product candidate updates. According to MBX Biosciences, presentations will cover scientific rationale and program status, followed by a live Q&A session.

Where can investors find the MBX Biosciences (MBX) Obesity Day webcast and replay after May 11, 2026?

The live webcast is accessible in the Events section of the MBX Biosciences investor website; a replay will be archived for about 90 days. According to MBX Biosciences, the replay link will remain available on the company site.

Will MBX Biosciences (MBX) provide time for audience questions during the May 11, 2026 presentation?

Yes. A live Q&A session will follow the formal presentations to allow audience questions. According to MBX Biosciences, management and invited speakers will participate in the live question-and-answer period.