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NeOnc Technologies (Nasdaq: NTHI) to Host Investor Conference Call to Present Data Updates from Ongoing NEO100-1 Phase 1/2a Clinical Trial and Compassionate Use Program

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NeOnc Technologies (Nasdaq: NTHI) will host an investor conference call and webcast on Wednesday, November 12, 2025 at 6:00 a.m. PT / 9:00 a.m. ET (prior to market open).

Management and independent Scientific Advisory Board members will present data updates from the ongoing Phase 1/2a NEO100-1 trial and compassionate use program, covering intranasal NEO100 (high-purity perillyl alcohol) in recurrent high-grade malignant glioma patients. Presentations will highlight MRI-based radiographic responses, progression-free survival (PFS), and overall survival (OS) trends observed to date. The live webcast will be available at https://investors.neonc.com.

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News Market Reaction 1 Alert

+2.74% News Effect
+$5M Valuation Impact
$171M Market Cap
0.7x Rel. Volume

On the day this news was published, NTHI gained 2.74%, reflecting a moderate positive market reaction. This price movement added approximately $5M to the company's valuation, bringing the market cap to $171M at that time.

Data tracked by StockTitan Argus on the day of publication.

CALABASAS, Calif., Nov. 07, 2025 (GLOBE NEWSWIRE) -- NeOnc Technologies Holdings, Inc. (NTHI) (“NeOnc” or the “Company”), a clinical-stage biopharmaceutical company developing novel brain-penetrant therapeutics for patients with malignant brain tumors and central nervous system (CNS) disorders, today announced that it will host an investor conference call and webcast on Wednesday, November 12, 2025, at 6:00 a.m. Pacific Time / 9:00 a.m. Eastern Time (prior to market open).

During the call, members of the NTHI management team and independent members of the company’s Scientific Advisory Board (SAB) will present data updates from the Company’s ongoing Phase 1/2a NEO100-1 clinical trial and compassionate use program, evaluating intranasal delivery of NEO100 (high-purity perillyl alcohol) in patients with recurrent high grade malignant glioma.

The discussion will highlight MRI-based radiographic response data, progression-free survival (PFS), and overall survival (OS) trends observed to date, providing important insights into long-term clinical outcomes for patients treated with NEO100.

Featured Participants:

  • Dr. Henry S. Friedman, MD – Deputy Director, Preston Robert Tisch Brain Tumor Center, Duke University; Independent Member, NTHI Scientific Advisory Board
  • Dr. Alexander Miller, MD – Chief Neuro-oncology, Brain Tumor Program, NYU Langone Health; Independent Member, NTHI Scientific Advisory Board
  • NTHI Management Team:
    • Amir Heshmatpour – Chief Executive Officer, Executive Chairman and President
    • Dr. Thomas C. Chen, MD, PhD – Chief Medical Officer and Chief Scientific Officer
    • Dr. Josh Neman, PhD – Chief Clinical Officer
    • Keith Garnett – Chief Financial Officer

Conference Call Details:

  • Date: Wednesday, November 12, 2025
  • Time: 6:00 a.m. PT / 9:00 a.m. ET
  • Webcast: A live webcast can be accessed by visiting https://investors.neonc.com

ABOUT NEONC TECHNOLOGIES HOLDINGS, INC.
NeOnc Technologies Holdings, Inc. is a clinical-stage life sciences company focused on the development and commercialization of central nervous system therapeutics that are designed to address the persistent challenges in overcoming the blood-brain barrier. The company’s NEO™ drug development platform has produced a portfolio of novel drug candidates and delivery methods with patent protections extending to 2038. These proprietary chemotherapy agents have demonstrated positive effects in laboratory tests on various types of cancers and in clinical trials treating malignant gliomas. NeOnc’s NEO100™ and NEO212™ therapeutics are in Phase II human clinical trials and are advancing under FDA Fast-Track and Investigational New Drug (IND) status. The company has exclusively licensed an extensive worldwide patent portfolio from the University of Southern California consisting of issued patents and pending applications related to NEO100, NEO212, and other products from the NeOnc patent family for multiple uses, including oncological and neurological conditions.

For more about NeOnc and its pioneering technology, visit neonc.com.

Important Cautions Regarding Forward-Looking Statements
This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements can be identified by terminology such as “may,” “will,” “should,” “intend,” “expect,” “plan,” “budget,” “forecast,” “anticipate,” “believe,” “estimate,” “predict,” “potential,” “continue,” “evaluating,” or similar words. Statements that contain these words should be read carefully, as they discuss our future expectations, projections of future results of operations or financial condition, or other forward-looking information.

Examples of forward-looking statements include, among others, statements regarding whether a definitive agreement will be reached with Quazar. These statements reflect our current expectations based on information available at this time, but future events may differ materially from those anticipated.

The “Risk Factors” section of our most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission, along with other cautionary language in that report or in our subsequent filings, outlines important risks and uncertainties. These may cause our actual results to differ materially from the forward-looking statements herein, including but not limited to the failure to finalize the agreement with Quazar, modifications to its terms, or alternative uses of proceeds.

We assume no obligation to revise or update any forward-looking statements, whether as a result of new information, future developments, or otherwise, except as required by applicable securities laws and regulations.

“NEO100” and NEO “212” are registered trademarks of NeOnc Technologies Holdings, Inc.

Company Contact:
info@neonc.com

Investor Contact:
James Carbonara
Hayden IR
(646)-755-7412
James@haydenir.com


FAQ

When is the NeOnc (NTHI) investor conference call to present NEO100-1 data?

The call is scheduled for Wednesday, November 12, 2025 at 6:00 a.m. PT / 9:00 a.m. ET.

What clinical data will NeOnc (NTHI) present on the November 12, 2025 call?

The company will present MRI-based radiographic responses, progression-free survival (PFS), and overall survival (OS) trends from the NEO100-1 trial and compassionate use program.

How can investors access the NeOnc (NTHI) November 12, 2025 webcast?

The live webcast is available at https://investors.neonc.com.

Which NeOnc (NTHI) speakers will present NEO100 clinical updates on November 12, 2025?

Featured presenters include SAB members Dr. Henry S. Friedman and Dr. Alexander Miller plus the NeOnc management team including CEO Amir Heshmatpour and CMO Thomas C. Chen.

What is the investigational therapy discussed by NeOnc (NTHI) on the November 12, 2025 call?

The therapy is NEO100, a high-purity perillyl alcohol administered via intranasal delivery in recurrent high-grade malignant glioma patients.
NeOnc Technologies Holdings Inc

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