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Publication relating to transparency notifications

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Nyxoah (NASDAQ: NYXH) published a transparency notification on October 3, 2025 reporting a holding change by Vestal Point Capital.

Per the notification dated September 30, 2025, Vestal Point Capital, LP now holds 1,113,575 voting rights, representing 2.97% of total voting rights (denominator: 37,544,782) as of September 24, 2025. The filing notes a downward crossing of the 3% threshold. Vestal Point Capital, LLC is the GP controlled by Ryan Wilder; Vestal Point Capital, LP acts as investment manager and may exercise voting rights at its discretion.

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On the day this news was published, NYXH gained 17.17%, reflecting a significant positive market reaction.

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REGULATED INFORMATION

Publication relating to transparency notifications

Mont-Saint-Guibert (Belgium), October 3, 2025, 10:30 pm CET / 4:30 pm ET In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

Vestal Point Capital

On October 1, 2025, Nyxoah received a transparency notification from Vestal Point Capital following an acquisition or disposal of voting securities or voting rights. Based on the notification, Vestal Point Capital holds 1,113,575 voting rights, representing 2.97% of the total number of voting rights on September 24, 2025 (37,544,782).

The notification dated September 30, 2025 contains the following information:

  • Reason for the notification:
    • Acquisition or disposal of voting securities or voting rights
    • Downward crossing of the lowest threshold
  • Notification by: a parent undertaking or a controlling person
  • Persons subject to the notification requirement:
    • Vestal Point Capital, LLC (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
    • Vestal Point Capital, LP (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
    • Ryan Wilder (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
  • Date on which the threshold was crossed: September 24, 2025
  • Threshold that is crossed: 3%
  • Denominator: 37,544,782
  • Notified details:
A) Voting rightsPrevious notificationAfter the transaction
 # of voting rights# of voting rights% of voting rights
Holders of voting rights Linked to securitiesNot linked to the securitiesLinked to securitiesNot linked to the securities
Ryan Wilder0000.00%0.00%
Vestal Point Capital, LLC0000.00%0.00%
Vestal Point Capital, LP1,809,8431,113,575 02.97%0.00%
Subtotal1,809,8431,113,575  2.97% 
 TOTAL1,113,575  2.97% 
  • Full chain of controlled undertakings through which the holding is effectively held: Vestal Point Capital, LP (investment manager) is controlled by Vestal Point Capital, LLC (general partner). Vestal Point Capital, LLC is controlled by Mr. Ryan Wilder (managing member).
  • Additional information: Vestal Point Capital, LP is the investment management company that can exercise the voting rights at its discretion, in the absence of specific instruction.

*

* *

Contact:
Nyxoah
John Landry, CFO
IR@nyxoah.com

Attachment


FAQ

What did Nyxoah (NYXH) disclose in the October 3, 2025 transparency notification?

Nyxoah disclosed Vestal Point Capital holds 1,113,575 voting rights (2.97%), crossing below the 3% threshold as of September 24, 2025.

When did Vestal Point Capital cross the 3% voting rights threshold in Nyxoah (NYXH)?

The threshold was crossed on September 24, 2025, per the notification dated September 30, 2025.

How many total voting rights does Nyxoah (NYXH) have according to the filing?

The filing uses a denominator of 37,544,782 total voting rights.

Who controls Vestal Point Capital's holdings in Nyxoah (NYXH)?

Vestal Point Capital, LP is the investment manager controlled by Vestal Point Capital, LLC, which is controlled by Ryan Wilder.

Does the transparency notification for NYXH indicate a change in voting control or special arrangements?

No special voting arrangements were disclosed; Vestal Point Capital, LP may exercise voting rights at its discretion absent specific instructions.

Will the Vestal Point Capital change likely trigger further regulatory filings for Nyxoah (NYXH)?

The filing only reports a downward crossing of 3%; further filings would depend on future acquisitions or disposals crossing other regulatory thresholds.
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