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Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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Orchestra BioMed (Nasdaq: OBIO) announced that on November 24, 2025 its Compensation Committee granted stock options to purchase an aggregate of 151,250 shares of common stock to 12 newly hired employees under the company’s 2025 New Hire Inducement Plan, pursuant to Nasdaq Listing Rule 5635(c)(4).

Per the awards, 25% of each grantee’s options vest on the first anniversary of employment, with the remainder vesting ratably each quarter over the following three years. The company provided these details to comply with Nasdaq disclosure requirements.

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Positive

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Negative

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News Market Reaction

+1.53%
6 alerts
+1.53% News Effect
+$4M Valuation Impact
$286M Market Cap
0.6x Rel. Volume

On the day this news was published, OBIO gained 1.53%, reflecting a mild positive market reaction. Our momentum scanner triggered 6 alerts that day, indicating moderate trading interest and price volatility. This price movement added approximately $4M to the company's valuation, bringing the market cap to $286M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Inducement options: 151,250 shares New employees: 12 employees Initial vesting: 25% +1 more
4 metrics
Inducement options 151,250 shares Stock options granted to new hires on November 24, 2025
New employees 12 employees Recipients under 2025 New Hire Inducement Plan
Initial vesting 25% Portion of each grant vesting on first work anniversary
Remainder vesting period 3 years Remaining options vest quarterly over next three years

Market Reality Check

Price: $4.13 Vol: Volume 144,369 is below t...
low vol
$4.13 Last Close
Volume Volume 144,369 is below the 345,865 20-day average (about 0.42x typical activity). low
Technical Price $4.57 is trading above the $3.29 200-day moving average, indicating a prior upward trend.

Peers on Argus

OBIO gained 11.19% while peers were mixed: GLSI up 10.93%, CYBN up 4.83%, PLX an...

OBIO gained 11.19% while peers were mixed: GLSI up 10.93%, CYBN up 4.83%, PLX and THTX modestly positive, and SGMO down 4.35%, suggesting a more stock-specific move than a broad sector trend.

Historical Context

5 past events · Latest: Dec 08 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Dec 08 Conference presentations Positive -0.2% Cardiology meeting presentations on AVIM Therapy and Virtue SAB programs.
Nov 26 Inducement grants Neutral +1.5% Stock option inducement grants disclosed under Nasdaq Rule 5635(c)(4).
Nov 11 Investor conferences Positive +8.5% Participation in late-2025 institutional investor conferences and webcast.
Nov 10 Q3 2025 earnings Positive -0.8% Q3 results plus substantial strategic capital extending cash runway into 2027.
Nov 03 Business update call Positive +1.3% Planned call on clinical, strategic and financing developments with partners.
Pattern Detected

Recent news has often seen modest price responses, with a mix of aligned and divergent reactions around clinical, financing, and corporate events.

Recent Company History

Over the last few months, Orchestra BioMed reported multiple strategic and financing milestones. An October 8-K detailed a Terumo preferred stock investment and Virtue SAB trial enrollment. A subsequent 10-Q and Q3 update highlighted $147.6 million in strategic capital and cash extending runway into Q4 2027. November brought a business update call, conference participation, and presentations on AVIM and Virtue SAB. The current inducement option grants under Nasdaq Rule 5635(c)(4) fit into routine corporate and governance activity rather than a new clinical or financing catalyst.

Regulatory & Risk Context

Active S-3 Shelf · $7.3 million
Shelf Active
Active S-3 Shelf Registration 2025-10-31
$7.3 million registered capacity

An effective resale shelf on Form S-3 registers up to 8,027,890 shares for selling stockholders. Orchestra BioMed does not receive proceeds from these resales but may receive up to $7.3 million if the Ligand warrant at $3.67 per share is exercised for cash.

Market Pulse Summary

This announcement outlines inducement stock option grants for 12 new employees covering 151,250 shar...
Analysis

This announcement outlines inducement stock option grants for 12 new employees covering 151,250 shares under Nasdaq Listing Rule 5635(c)(4), with 25% vesting after one year and the balance over three years. It is primarily a governance and compensation disclosure rather than a new clinical or financing catalyst. In the broader backdrop, recent filings describe significant strategic capital, a resale registration, and ongoing clinical programs, which remain key elements to watch.

Key Terms

nasdaq listing rule 5635(c)(4)
1 terms
nasdaq listing rule 5635(c)(4) regulatory
"granted stock options ... in accordance with Nasdaq Listing Rule 5635(c)(4)."
NASDAQ Listing Rule 5635(c)(4) is a rule that requires a company to get approval from its shareholders before selling a large amount of its shares, usually over 20%. This helps protect investors by making sure the company doesn't flood the market with new shares without their say, which could lower the stock's value.

AI-generated analysis. Not financial advice.

NEW HOPE, Pa., Nov. 26, 2025 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through strategic partnerships with market-leading global medical device companies, reported today that, on November 24, 2025, the Compensation Committee of the Orchestra BioMed Board of Directors granted stock options to purchase an aggregate of 151,250 shares of the Company’s common stock to 12 newly hired employees. The awards were granted pursuant to the Orchestra Biomed Holdings, Inc. 2025 New Hire Inducement Plan as an inducement material to each new employee entering employment with Orchestra Biomed, in accordance with Nasdaq Listing Rule 5635(c)(4).

Twenty-five percent of the stock options granted to each new employee will vest on the first anniversary of the date such employee commenced employment with the Company, with the remainder vesting ratably each quarter over the following three-year period.

Orchestra Biomed is providing this information in accordance with Nasdaq Listing Rule 5635(c)(4).

About Orchestra BioMed
Orchestra BioMed is a biomedical innovation company accelerating high-impact technologies to patients through strategic collaborations with market-leading global medical device companies. The Company’s two flagship product candidates - Atrioventricular Interval Modulation (AVIM) Therapy and Virtue® Sirolimus AngioInfusion™ Balloon (Virtue SAB) - are currently undergoing pivotal clinical trials for their lead indications, each representing multi-billion-dollar annual global market opportunities. AVIM Therapy is a bioelectronic treatment for hypertension, the leading risk factor for death worldwide, and is designed to be delivered as a firmware upgrade to a pacemaker and achieve immediate, substantial and sustained reductions in blood pressure in patients with hypertensive heart disease. The Company has a strategic collaboration with Medtronic, one of the largest medical device companies in the world, for the development and commercialization of AVIM Therapy for the treatment of uncontrolled hypertension in pacemaker-indicated patients. AVIM Therapy has FDA Breakthrough Device Designation for these patients, as well as an estimated 7.7 million total patients in the U.S. with uncontrolled hypertension despite medical therapy and increased cardiovascular risk. Virtue SAB is a highly differentiated, first-of-its-kind drug delivery angioplasty balloon system designed to deliver a proprietary extended-release formulation of sirolimus, SirolimusEFR™, for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Virtue SAB has been granted Breakthrough Device Designation by the FDA for the treatment of coronary ISR, coronary small vessel disease and below-the-knee peripheral artery disease. For further information about Orchestra BioMed, please visit www.orchestrabiomed.com, and follow us on LinkedIn.

Investor Contact:
Silas Newcomb
Orchestra BioMed
Snewcomb@orchestrabiomed.com

Media Contact:
Kelsey Kirk-Ellis
Orchestra BioMed
kkirkellis@orchestrabiomed.com


FAQ

How many shares did Orchestra BioMed (OBIO) grant on November 24, 2025?

Orchestra BioMed granted stock options to purchase an aggregate of 151,250 shares on November 24, 2025.

How many employees received inducement option grants from OBIO on November 24, 2025?

12 newly hired employees received option grants under the 2025 New Hire Inducement Plan.

What is the vesting schedule for OBIO inducement options granted November 24, 2025?

25% vests on the first employment anniversary, then the remainder vests ratably each quarter over the next three years.

Why did Orchestra BioMed (OBIO) disclose these stock option grants?

The disclosure was made to comply with Nasdaq Listing Rule 5635(c)(4), which covers inducement awards for newly hired employees.

Do the November 24, 2025 OBIO option grants immediately dilute existing shareholders?

The grants are options to purchase shares and do not represent immediate share issuance; dilution would occur only if and when the options are exercised.
Orchestra BioMed Holdings Inc

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OBIO Stock Data

230.94M
39.53M
16.13%
34.97%
1.43%
Biotechnology
Surgical & Medical Instruments & Apparatus
Link
United States
NEW HOPE