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BeOne Medicines Ltd. Stock Price, News & Analysis

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Welcome to our dedicated page for BeOne Medicines Ltd. news (Ticker: ONC), a resource for investors and traders seeking the latest updates and insights on BeOne Medicines Ltd. stock.

BeOne Medicines Ltd. (ONC) generates a steady flow of oncology news that reflects its focus on hematology and solid tumors. As a Switzerland‑domiciled global oncology company with listings on NASDAQ, the Hong Kong Stock Exchange and the STAR Market in Shanghai, BeOne regularly issues updates on clinical data, regulatory milestones, financial performance and corporate developments.

Investors and healthcare professionals following ONC news will see frequent announcements related to B‑cell malignancies, especially chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). The company highlights new data for its BTK inhibitor BRUKINSA, including long‑term results from Phase 3 trials such as SEQUOIA and ALPINE, as well as patient‑reported outcomes and guideline updates. News also covers sonrotoclax, an investigational BCL2 inhibitor, with items on FDA Breakthrough Therapy Designation, Priority Review for relapsed or refractory MCL, and clinical results in CLL and other B‑cell cancers. Updates on BTK degrader BGB‑16673 from the CaDAnCe clinical program appear alongside these hematology releases.

On the solid tumor side, BeOne’s news includes Phase 3 trial results for ZIIHERA (zanidatamab) plus TEVIMBRA (tislelizumab) and chemotherapy in first‑line HER2‑positive gastroesophageal adenocarcinoma, as well as regulatory plans based on these data. Additional releases describe TEVIMBRA’s expanding indications and BGB‑B2033’s FDA Fast Track Designation in hepatocellular carcinoma. Financial news items provide quarterly revenue, product sales trends for BRUKINSA and TEVIMBRA, cash flow metrics and updated guidance, while corporate updates cover conference presentations, research milestones and agreements such as the IMDELLTRA royalty purchase arrangement with Royalty Pharma.

For users tracking ONC, this news stream offers insight into BeOne’s evolving hematology and solid tumor portfolios, its regulatory interactions in major markets and its stated goal of broadening patient access to cancer therapies. Bookmarking the ONC news page on Stock Titan allows readers to follow company press releases, clinical milestones and financial disclosures in one place.

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BeOne Medicines (NASDAQ: ONC) has announced an upcoming Investor R&D Day event scheduled for June 26, 2025, at 8:30 am ET, to be held in New York City with a simultaneous webcast option. The event will feature presentations from CEO John V. Oyler and the company's leadership team, along with key opinion leaders. They will provide updates on BeOne's global innovation pipeline, platforms, new assets, targets, and clinical data. The company will also share insights on its vision, capabilities, and value creation strategies. Investors can access the webcast through BeOne's investor relations websites, with registration recommended 15 minutes before the event. An archived version will be available afterward.
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BeOne Medicines (NASDAQ: ONC) presented promising clinical data for two breast cancer therapies at ASCO 2025. The first drug, BG-C9074, a B7-H4-targeting antibody-drug conjugate (ADC), showed a 16.1% confirmed overall response rate and 73.2% disease control rate in 56 evaluable patients with advanced solid tumors. The second drug, BG-68501, a CDK2 inhibitor, demonstrated a 5.4% overall response rate in 37 evaluable patients, with two breast cancer patients achieving partial responses. Both drugs exhibited manageable safety profiles. BG-C9074's most common adverse events included nausea, fatigue, and neutropenia, while BG-68501's included vomiting, nausea, and fatigue. These preliminary results suggest potential new treatment options for breast cancer patients, particularly addressing resistance mechanisms in HR+/HER2- breast cancer patients previously treated with CDK4/6 inhibitors.
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BeOne Medicines presented new data from the Phase 3 SEQUOIA trial of BRUKINSA (zanubrutinib) at ASCO 2025, demonstrating strong efficacy in CLL treatment. The trial's Arm D showed BRUKINSA plus venetoclax achieved a 92% 24-month progression-free survival rate and 97% overall response rate. In high-risk del(17p)/TP53 mutation patients, 87.6% remained progression-free at 36 months. The Arm C 5-year follow-up showed sustained benefits with BRUKINSA monotherapy, with 72.2% of del(17p) patients remaining progression-free at 60 months. The best undetectable minimal residual disease rate in peripheral blood was 59%, with 11 patients able to discontinue treatment early while maintaining remission. The safety profile remained consistent with previous studies, with no new safety signals identified.
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BeOne Medicines (NASDAQ: ONC), formerly BeiGene, announced its official redomiciliation to Switzerland and rebranding. The company, a global oncology leader, highlighted its significant achievements including BRUKINSA's market leadership and a robust pipeline of over 50 investigational assets. In 2024, BeOne's research team of 1,100+ colleagues launched 13 new molecular entities into clinical trials. The company's clinical development team of 3,700 members manages trials across 45+ countries, having enrolled 25,000+ patients in 170+ trials. BeOne is expanding its global presence with an $800 million manufacturing facility in Hopewell, NJ. The company focuses on hematology with BRUKINSA, TEVIMBRA (PD-1 inhibitor), and is developing treatments for breast, lung, and gastrointestinal cancers.

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BeiGene received a positive CHMP opinion recommending approval of TEVIMBRA® in combination with chemotherapy for first-line treatment of nasopharyngeal cancer (NPC). The recommendation is based on the RATIONALE-309 Phase 3 study results, which showed significant improvements in patient outcomes. The study demonstrated: - Median progression-free survival of 9.2 months for TEVIMBRA with chemotherapy vs 7.4 months for placebo - Median overall survival of 45.3 months vs 31.8 months for placebo - Hazard ratio of 0.52 [95% CI:0.38, 0.73] p<0.0001 This marks TEVIMBRA's second positive CHMP opinion in 2025, with the drug already approved in major markets including the US, EU, China, and Japan for various cancer indications. The treatment showed a manageable safety profile with no new safety signals identified.
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BeiGene (NASDAQ: ONC) will present 23 abstracts at the 2025 ASCO Annual Meeting (May 30-June 3) showcasing their oncology portfolio. Key highlights include:

Two rapid oral presentations featuring BRUKINSA® (zanubrutinib) data from the SEQUOIA trial in chronic lymphocytic leukemia (CLL), including: - Long-term follow-up results from Arm C in treatment-naïve CLL patients with del(17p) mutations - First results from Arm D evaluating BRUKINSA plus venetoclax combination therapy

The company will present early-phase data for novel breast cancer treatments: - BG-C9074: A B7-H4-targeting antibody-drug conjugate for advanced solid tumors - BG-68501: A CDK2 inhibitor for HR+/HER2- breast cancer - TEVIMBRA®: Final analysis showing promising efficacy in esophageal squamous cell carcinoma

The presentations demonstrate BeiGene's commitment to advancing cancer treatment across multiple fronts, from hematologic malignancies to solid tumors.

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BeiGene (NASDAQ: ONC) will present extensive data from its hematology portfolio at the EHA 2025 Congress in Milan, featuring 31 abstracts, including four oral presentations. The presentations highlight data from BRUKINSA® (zanubrutinib) and two investigational assets: sonrotoclax (BCL2 inhibitor) and BGB-16673 (BTK protein degrader). The pipeline assets have enrolled over 2,500 patients globally and show promising clinical activity in B-cell malignancies. Key highlights include updated Phase 1 results for BGB-16673 in CLL/SLL and WM patients, sonrotoclax's combination with BRUKINSA in various conditions, and results from the SEQUOIA study evaluating BRUKINSA in CLL/SLL patients. The company, soon to be renamed BeOne Medicines Ltd., aims to transform treatment standards in hematology through next-generation innovation.
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BeiGene (NASDAQ: ONC), a global oncology company, has announced its participation in the upcoming RBC Capital Markets Global Healthcare Conference. The company, which will be renamed to BeOne Medicines Ltd., will engage in a fireside chat on May 20, 2025, at 10 a.m. EDT. Investors can access the live webcast through the company's investor relations websites, and an archived replay will remain available for one year after the event.

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BeiGene (ONC) reported strong Q1 2025 financial results with total revenues increasing 49% to $1.1 billion. BRUKINSA global sales grew 62% to $792 million, leading in U.S. CLL patient starts. The company achieved its first GAAP profitability with net income of $1.27 million, compared to a $251.2 million loss in Q1 2024. U.S. product revenue reached $563 million, while European BRUKINSA sales grew 73% to $116 million. The company maintained its 2025 guidance of $4.9-5.3 billion in total revenue. BeiGene secured shareholder approval to rename to BeOne Medicines Ltd. and redomicile to Switzerland. The company continues advancing its late-stage hematology and solid tumor pipelines, with multiple proof-of-concept readouts expected this year across antibody-drug conjugates, multispecific antibodies, and targeted protein degraders.
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BeiGene has secured a significant legal victory as the U.S. Patent and Trademark Office (USPTO) invalidated all challenged claims of Pharmacyclics' Patent No. 11,672,803. This ruling comes in response to BeiGene's post-grant review petition filed on November 1, 2023, following Pharmacyclics' patent infringement lawsuit regarding BRUKINSA (zanubrutinib).

The USPTO's Final Written Decision, while appealable by Pharmacyclics, supports BeiGene's position that the '803 patent was overly broad and invalid. BRUKINSA, BeiGene's independently developed medicine for B-cell malignancies, has received approvals in over 70 countries and regions.

BeiGene, which plans to change its name to BeOne Medicines, maintains confidence in their intellectual property rights supporting BRUKINSA, which continues to establish new standards in patient care worldwide.

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FAQ

What is the current stock price of BeOne Medicines Ltd. (ONC)?

The current stock price of BeOne Medicines Ltd. (ONC) is $361.568 as of February 20, 2026.

What is the market cap of BeOne Medicines Ltd. (ONC)?

The market cap of BeOne Medicines Ltd. (ONC) is approximately 39.2B.

ONC Rankings

ONC Stock Data

39.23B
90.63M
Biotechnology
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