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OpenBench and ORIC Pharmaceuticals Launch Success-Driven Discovery Collaboration

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OpenBench and ORIC Pharmaceuticals (NASDAQ: ORIC) have launched a collaborative effort to enhance early drug discovery for an undisclosed oncology target. The partnership aims to leverage OpenBench's AI-enabled success-driven small molecule discovery approach and structure-based machine learning platform to complement ORIC's resistance platform in targeting cancer-specific vulnerabilities.

Under the agreement, OpenBench will receive payment for identifying novel small molecule chemotypes that meet ORIC's specified activity and developability criteria. In return, ORIC gains exclusive rights to the discovered leads and access to OpenBench's proprietary screening technology for the target of interest. While specific financial terms were not disclosed, this collaboration represents a strategic move to combine OpenBench's innovative discovery platform with ORIC's expertise in addressing mechanisms of therapeutic resistance in oncology.

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Positive

  • Potential for accelerated drug discovery process in oncology
  • Access to OpenBench's AI-enabled platform and proprietary screening technology for ORIC
  • Exclusive rights to discovered leads for ORIC
  • Payment structure tied to successful identification of novel small molecule chemotypes

Negative

  • None.

News Market Reaction 1 Alert

+1.10% News Effect

On the day this news was published, ORIC gained 1.10%, reflecting a mild positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

SAN FRANCISCO, Sept. 17, 2024 /PRNewswire/ -- OpenBench, Inc., a pioneer in AI-enabled success-driven small molecule discovery partnerships, today announced the launch of a collaboration with ORIC Pharmaceuticals, Inc. (NASDAQ: ORIC), a clinical stage oncology company focused on developing treatments that address mechanisms of therapeutic resistance. The parties aim to apply OpenBench's success-driven discovery approach and structure-based machine learning platform to enrich early discovery efforts against an undisclosed target identified by ORIC's resistance platform to target cancer-specific vulnerabilities.

Under the terms of the agreement, OpenBench will receive payment upon the identification of novel small molecule chemotypes and the experimental confirmation that they meet certain activity and developability criteria defined by ORIC®. In exchange, ORIC will gain full and exclusive rights to discovered leads and access to OpenBench's proprietary screening technology with respect to the target of interest. Detailed financial terms were not disclosed.

"We are excited to join forces with the ORIC Pharmaceuticals team to enrich their early discovery efforts against an undruggable target," said OpenBench CEO James Yoder. "We are confident OpenBench's success-driven early discovery platform will complement ORIC's innovative approach to tackling therapeutic challenges."

About OpenBench

OpenBench is pioneering success-driven collaborations to bring rigor to AI-enabled early discovery. OpenBench bears the cost of virtual screening, custom synthesis, and experimental confirmation to ensure that the first dollar our partners spend is to purchase potent, developable leads. OpenBench's proprietary structure-based machine learning platform uniquely enables the success-driven model and has succeeded in finding quality, progressible chemical matter for more than 90% of targets we have taken on to date. To learn more, contact OpenBench at discovery@opnbnch.com or visit www.opnbnch.com

Contact: James Yoder, contact@opnbnch.com

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/openbench-and-oric-pharmaceuticals-launch-success-driven-discovery-collaboration-302250595.html

SOURCE OpenBench

FAQ

What is the purpose of the collaboration between OpenBench and ORIC Pharmaceuticals?

The collaboration aims to enhance early drug discovery efforts against an undisclosed oncology target by combining OpenBench's AI-enabled success-driven small molecule discovery approach with ORIC's resistance platform to target cancer-specific vulnerabilities.

What will OpenBench receive from this collaboration with ORIC Pharmaceuticals?

OpenBench will receive payment upon the identification of novel small molecule chemotypes that meet certain activity and developability criteria defined by ORIC Pharmaceuticals.

What rights does ORIC Pharmaceuticals gain from this collaboration?

ORIC Pharmaceuticals gains full and exclusive rights to the discovered leads and access to OpenBench's proprietary screening technology for the target of interest.

When was the collaboration between OpenBench and ORIC Pharmaceuticals announced?

The collaboration between OpenBench and ORIC Pharmaceuticals was announced on September 17, 2024.
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