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Ovid Therapeutics to Host Potassium-Chloride Co-transporter 2 (KCC2) Deep Dive R&D Event on Tuesday, April 14

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Ovid Therapeutics (Nasdaq: OVID) will host a KCC2 Deep Dive R&D event on Tuesday, April 14, 2026 at 9:30 am ET in New York, with a simultaneous webcast. The session will review Ovid's first-in-class KCC2 portfolio, pharmacodynamic data, translational and clinical strategy, and market potential.

Speakers include CEO Meg Alexander, independent clinicians, translational experts, and leading neuroscientists; a webcast replay will be archived for 90 days.

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Negative

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News Market Reaction – OVID

+1.56%
61 alerts
+1.56% Session close to close
+13.6% Peak in 2 hr 28 min
$407.49M Market Cap
0.6x Rel. Volume

In the Apr 8 session, OVID gained 1.56%, reflecting a mild positive market reaction. Argus tracked a peak move of +13.6% during that session. Our momentum scanner triggered 61 alerts that day, indicating high trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights an in-depth KCC2 R&D event on April 14, 2026, emphasizing OVID’s portfo...
Analysis

This announcement highlights an in-depth KCC2 R&D event on April 14, 2026, emphasizing OVID’s portfolio of direct KCC2 activators, including OV350, OV4071 and next-generation candidates targeting neurological and neuropsychiatric disorders. It reinforces the company’s strategic focus on KCC2 mechanisms previously described in filings and news. Investors may watch for new pharmacodynamic insights, translational plans, and any clinical or commercial guidance shared at the event, alongside how this complements recent OV329 and OV4071 program updates.

Key Figures

R&D event date: April 14, 2026 Event time: 9:30 am ET Webcast replay period: 90 days
3 metrics
R&D event date April 14, 2026 KCC2 Deep Dive R&D event in New York
Event time 9:30 am ET Start time of KCC2 Deep Dive R&D event
Webcast replay period 90 days Replay of the webcast available on Ovid’s website

Historical Context

5 past events · Latest: Mar 18 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 18 Data & earnings Positive +14.4% OV329 data, OV4071 Phase 1 clearance, and 2025 financial results.
Mar 18 Private placement Neutral +14.4% Announcement of $60.0M PIPE financing and related share, warrant terms.
Feb 25 Investor conferences Positive +7.3% Participation in three investor conferences with webcast access.
Dec 18 Phase 1 results Neutral -9.5% OV350 Phase 1 safety/PK success but IV program not advanced further.
Dec 02 Leadership change Positive -13.3% Appointment of Dr. Petra Kaufmann as Chief Medical Officer.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent OVID news often drew sizable moves, with generally positive reactions to data/financing updates but occasional selloffs on leadership or pipeline restructuring headlines.

Recent Company History

Over the past six months, OVID has highlighted key CNS pipeline advances and financing. On Mar 18, 2026, OV329 data, OV4071 Phase 1 clearance, and 2025 results coincided with a 14.43% gain, alongside a $60.0M private placement the same day that saw a similar move. Earlier, conference participation on Feb 25, 2026 led to a 7.28% rise. In late 2025, OV350 Phase 1 results and the decision not to advance the IV program, plus a CMO appointment, saw declines. Today’s KCC2 R&D event builds directly on this KCC2-focused narrative.

Key Terms

potassium-chloride co-transporter 2 (KCC2), KCC2, pharmacodynamic, translational, +1 more
5 terms
potassium-chloride co-transporter 2 (KCC2) medical
"to Host Potassium-Chloride Co-transporter 2 (KCC2) Deep Dive R&D event"
Potassium-chloride co-transporter 2 (KCC2) is a protein in nerve cells that moves potassium and chloride ions across the cell membrane to keep electrical activity and signaling stable. Think of it as a household valve that keeps the salt and water balance right so wiring inside the house doesn’t short out. Investors watch KCC2 because drugs or tests that change its activity can alter treatment prospects for neurological conditions, shaping clinical, regulatory and commercial value.
KCC2 medical
"its first-in-class KCC2 portfolio on Tuesday, April 14, 2026"
KCC2 is a protein made by nerve cells that pumps chloride ions out of the cell, helping the brain’s inhibitory signals work properly; think of it as a tiny pump that keeps electrical balance so neurons don’t get overexcited. Investors care because changes in KCC2 function are linked to neurological and psychiatric disorders, making it a potential drug target or biomarker whose successful therapies or approvals could drive clinical value and commercial opportunities.
pharmacodynamic medical
"including pharmacodynamic data, translational and clinical development strategy"
Pharmacodynamic describes how a drug acts on the body — the biological effects it produces, how strong those effects are, and how long they last. For investors, pharmacodynamic data show whether a treatment actually works and at what dose, shaping expectations about a drug’s safety, effectiveness, regulatory success and market potential; think of it like testing how well a key turns a lock and whether it reliably opens the door.
translational medical
"independent expert clinicians and translational experts as well as Ovid’s President"
Translational describes the process of turning basic scientific discoveries into practical medical tests, treatments or products that can be used with patients. For investors it signals how close a technology is to real-world use and potential revenue — like converting a prototype into a factory-made product — so strong translational progress can reduce technical risk and increase the chances of commercial returns.
neuropsychiatric medical
"for neurological and neuropsychiatric conditions including various psychoses"
Conditions or symptoms that involve both the brain’s biology and a person’s mood, thinking or behavior; they sit at the intersection of neurology and psychiatry. Investors care because neuropsychiatric issues often require specialized drugs, devices or diagnostics, carry distinct regulatory and safety risks, and can affect patient populations and market size — think of them as disorders where hardware (brain circuitry) and software (behavior) problems overlap.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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NEW YORK, April 08, 2026 (GLOBE NEWSWIRE) -- Ovid Therapeutics Inc. (Nasdaq: OVID), a biopharmaceutical company developing small molecule medicines for brain disorders with significant unmet need, today announced the Company will host a KCC2 Deep Dive R&D event highlighting its first-in-class KCC2 portfolio on Tuesday, April 14, 2026, at 9:30 am ET in New York, NY, which will also be webcast simultaneously.

During the event independent expert clinicians and translational experts as well as Ovid’s President and Chief Executive Officer Meg Alexander, will discuss the Company’s proprietary portfolio of potential first-in-class direct activators of KCC2, including pharmacodynamic data, translational and clinical development strategy, and the potential market opportunity. Ovid is developing a portfolio of unique molecules, which include OV350 (an intravenous tool program and KCC2 direct activator), OV4071 (an oral KCC2 direct activator) and next-generation development candidates that have differentiated potential therapeutic profiles and formulations. These direct activators have the potential to become broad franchises of medicines for neurological and neuropsychiatric conditions including various psychoses, epilepsies, and neurodevelopmental and neurodegenerative disorders.

The event will also feature remarks from multiple leading neuroscientists, including:

  • Michael Halassa, M.D., Ph.D., Professor, Patient Research Center, Fralin Biomedical Research Institute at VTC, Department of Psychiatry and Behavioral Medicine, Virginia Tech Carilion School of Medicine, Department of Biomedical Engineering, College of Engineering, Virginia Tech
  • Oliver Howes, M.B.B.S., Ph.D., Head of Department, Psychosis Studies, Professor of Molecular Psychiatry at the Institute of Psychiatry, Psychology & Neuroscience, King's College London
  • Eliseo Oeste Salinas, M.D., M.s.C., Senior R&D Advisor to Ovid and veteran drug developer

Webcast Information

Ovid will host a live webcast of the event at 9:30 am ET on Tuesday, April 14, 2026.

The live webcast of the event can be accessed through the Events & Presentations section of Ovid’s website. Participants may register for the webcast here and are advised to do so at least 10 minutes prior to joining the event. A replay of the webcast will be archived on Ovid’s website for 90 days following the event.

About Ovid Therapeutics

Ovid Therapeutics Inc. is a New York-based biopharmaceutical company dedicated to developing small molecule medicines for brain disorders with significant unmet need. Ovid is advancing a pipeline of novel targeted small molecule candidates that modulate the intrinsic and extrinsic factors involved in neuronal hyperexcitability causative of multiple neurological and neuropsychiatric disorders. Ovid is developing: OV329, a next-generation GABA-aminotransferase inhibitor, as a potential therapy for treatment-resistant focal onset seizures (FOS) and developmental and epileptic encephalopathies (DEEs), including tuberous sclerosis complex (TSC) and infantile spasms (IS); and OV4071 and others within a library of compounds that directly activate the KCC2 transporter for multiple CNS disorders. For more information about these and other Ovid research programs, please visit www.ovidrx.com.

Contact

Investor Relations & Media
Victoria Fort
VFort@ovidrx.com
202.361.0445


FAQ

When is Ovid Therapeutics' KCC2 Deep Dive R&D event and how can I watch the OVID webcast?

The event is Tuesday, April 14, 2026 at 9:30 am ET and will be webcast live. According to OVID, the live webcast can be accessed via the Events & Presentations section of the company's website and a replay will be archived for 90 days.

What topics will Ovid (NASDAQ: OVID) cover at the April 14, 2026 KCC2 Deep Dive R&D event?

Ovid will present pharmacodynamic data, translational and clinical development strategy, and market opportunity for its KCC2 portfolio. According to OVID, discussions will focus on direct KCC2 activators OV350, OV4071, and next-generation candidates and their therapeutic potential.

Which KCC2 drug candidates will Ovid discuss at the April 14, 2026 event (OVID)?

Ovid will highlight OV350 (intravenous tool program) and OV4071 (oral KCC2 direct activator) plus next-generation candidates. According to OVID, the portfolio represents their proprietary potential first-in-class direct activators of KCC2.

Will Ovid (OVID) provide clinical or pharmacodynamic data during the April 14 event?

Yes. Ovid will present pharmacodynamic data and translational and clinical development strategy during the event. According to OVID, the session will include data-driven discussion of the company's KCC2 direct activator programs and development plans.

How long will the Ovid (NASDAQ: OVID) webcast replay be available after the April 14, 2026 event?

The webcast replay will be archived for 90 days following the event. According to OVID, participants can access the replay via the Events & Presentations section of the company's website during that 90-day window.