Welcome to our dedicated page for Palisade Bio news (Ticker: PALI), a resource for investors and traders seeking the latest updates and insights on Palisade Bio stock.
Palisade Bio, Inc. develops next-generation oral PDE4 inhibitor prodrugs for inflammatory and fibrotic diseases. Its lead program, PALI-2108, is a once-daily oral PDE4 inhibitor prodrug designed for targeted delivery and selective bioactivation in the ileum and colon, with clinical development focused on ulcerative colitis and Crohn’s disease.
Company news commonly covers PALI-2108 clinical and translational data, pharmacokinetic and biomarker findings, disease-conference presentations, clinical advisory activity and healthcare investor events. Updates also describe the company’s precision pharmacology strategy and the role of gut-targeted PDE4 inhibition in inflammatory bowel disease programs.
Palisade Bio, Inc. (Nasdaq: PALI) has announced the promotion of Robert McRae to Chief Operating Officer, a move that underscores the company’s commitment to advancing therapies for gastrointestinal complications. McRae, who joined the company in December 2021, will now oversee corporate operations and strategic initiatives. His experience in clinical operations and partnership development is expected to enhance the ongoing work on LB1148, the company’s lead program, which is in Phase 2 trials aimed at reducing postoperative complications. This leadership change is positioned to strengthen execution and support the company’s long-term objectives.
Palisade Bio (Nasdaq: PALI) announced that holders of 1.46 million additional common stock purchase warrants exercised their rights, yielding gross cash proceeds of $3.65 million. This increases total proceeds from early warrant exercises to $4.9 million. The company believes the funds will extend its cash runway into the second half of 2024, supporting ongoing clinical studies. As of January 10, 2023, 92% of Series 1 Warrants and 81% of Series 2 Warrants have been exercised. Palisade Bio focuses on therapies for gastrointestinal complications and is working on its lead program, LB1148.
Palisade Bio (Nasdaq: PALI) announced that J.D. Finley, Interim CEO, will present at the Virtual Investor 2023 Companies to Watch Event on January 17, 2023, at 3:00 PM ET. A live video webcast of the presentation will be available on the company's website, with a replay accessible for 90 days. The company focuses on developing therapeutics to protect the intestinal barrier, with its lead program, LB1148, currently in a Phase 2 study to address post-surgical complications.
Palisade Bio has successfully closed its registered direct offering and concurrent private placement, raising funds by selling 1,052,631 shares at $2.375 each. The offering includes unregistered pre-funded warrants and Common Warrants with a five-year term at the same price. The proceeds will be allocated for working capital and general corporate purposes. These securities will not be registered under the Securities Act, although the company plans to file a registration statement for resale. The company focuses on developing therapeutics for gastrointestinal complications.
Palisade Bio (Nasdaq: PALI) announced a registered direct offering and concurrent private placement with institutional investors for the purchase of 1,052,631 shares at $2.375 per share. The offering will close around January 4, 2022. Investors will receive unregistered pre-funded warrants and common warrants for future shares. Proceeds will be used for working capital and general corporate purposes. The company also stated that it will file a registration statement for the resale of the shares linked to these warrants.
Palisade Bio, Inc. (Nasdaq: PALI) has provided an update on its Phase 2 study evaluating LB1148 for reducing intra-abdominal adhesions after bowel resection. The company has enrolled 35 out of the planned 70 patients and has decided to cease further enrollment to analyze collected data. Topline results from the 35 patients are expected in the first half of 2023. Furthermore, a dose optimization study is in the works to enhance LB1148's risk profile and efficacy, with enrollment anticipated to start in early 2023.
Palisade Bio (Nasdaq: PALI) has announced that it has received approximately $1.25 million after 445,000 common stock purchase warrants were exercised by shareholders. This financial boost is aimed at extending the company's cash runway into early 2024, aligning with the anticipated topline results from the Phase 2 study of LB1148, which targets post-surgical adhesions. The company is focused on developing therapies that enhance intestinal barrier integrity, with LB1148 showing promise in reducing complications associated with gastrointestinal surgeries.
Palisade Bio, Inc. (Nasdaq: PALI) has announced it has regained compliance with Nasdaq Listing Rules as of December 1, 2022. The company is focused on developing therapeutics for gastrointestinal complications, leveraging over three decades of research on intestinal barrier biology. Its lead program, LB1148, aims to neutralize digestive enzymes and mitigate intestinal damage, showing promising results in clinical studies for reducing post-surgical complications. The company emphasizes the potential for its therapies to transform treatment standards for related diseases.
Palisade Bio (Nasdaq: PALI), a clinical-stage biopharmaceutical company, announced that the FDA has granted Fast Track designation for its drug LB1148. This designation aims to expedite the return of bowel function after gastrointestinal surgery. LB1148 acts as a broad-spectrum serine protease inhibitor, neutralizing digestive enzymes to potentially reduce abdominal adhesions. CEO JD Finley highlighted this as a key regulatory milestone, emphasizing the unmet need for safer therapeutic options.
Palisade Bio has appointed Herbert B. Slade, MD, FAAAAI as its new Chief Medical Officer. With over 25 years in the pharmaceutical industry, Dr. Slade previously served as a clinical advisor for the company, contributing to the development of LB1148, a treatment for gastrointestinal complications. His extensive experience includes regulatory negotiations with the FDA and EMA, as well as significant leadership roles in clinical research. This transition aims to advance LB1148's potential as a standard of care for post-surgical gastrointestinal issues.