Welcome to our dedicated page for Precigen news (Ticker: PGEN), a resource for investors and traders seeking the latest updates and insights on Precigen stock.
Precigen Inc (PGEN) is a clinical-stage biopharmaceutical leader advancing next-generation gene and cell therapies through its proprietary synthetic biology platforms. This page aggregates official news, press releases, and regulatory developments related to PGEN's innovative research in immuno-oncology, autoimmune disorders, and infectious diseases.
Investors and industry professionals will find timely updates on clinical trial progress, strategic partnerships, and technological breakthroughs leveraging PGEN's UltraCAR-T and AdenoVerse platforms. The curated content supports informed decision-making by providing transparent access to the company's scientific advancements and operational milestones.
Key updates include announcements about therapeutic candidate developments, manufacturing innovations, and collaboration agreements that demonstrate PGEN's position at the forefront of precision medicine. All content is sourced directly from company communications to ensure accuracy and compliance.
Bookmark this page for streamlined access to Precigen's latest developments in gene-editing technologies and cellular therapeutics. Regularly updated to reflect PGEN's evolving pipeline and strategic initiatives.
On April 26, 2023, Precigen (Nasdaq: PGEN) announced its participation in the 2023 ASCO Annual Meeting from June 2-6, 2023, in Chicago, Illinois. The company will present clinical data on two innovative therapies: PRGN-3005 UltraCAR-T for advanced, recurrent platinum-resistant ovarian cancer and PRGN-2009 AdenoVerse immunotherapy for HPV-associated cancers. Highlights include:
- PRGN-3005: Phase 1/1b study demonstrating the potential of overnight manufactured UltraCAR-T cells.
- PRGN-2009: Phase 1 study evaluating its effectiveness alone and with an anti-PDL1/TGF-Beta trap checkpoint inhibitor.
Event details and updates can be found on Precigen's investor website.
Precigen, Inc. (Nasdaq: PGEN) presented preclinical data for its next-generation UltraCAR-T platform using a mesothelin (MSLN) CAR at the AACR Annual Meeting 2023. MSLN is overexpressed in various solid tumors including mesothelioma and pancreatic cancer.
The new UltraCAR-T cells feature a novel mechanism for intrinsic PD-1 blockade, aiming to enhance safety and efficacy by eliminating the need for expensive checkpoint inhibitors. Results showed robust UltraCAR-T cell expansion and durable persistence leading to significant antitumor effects in preclinical models, even after tumor rechallenges. Collectively, these findings position the UltraCAR-T platform as a promising candidate in the cancer treatment landscape.
Precigen (NASDAQ: PGEN) has amended its license agreement with Alaunos Therapeutics, regaining exclusive rights to IL-12 gene therapy and proven CAR-T targets CD19 and BCMA. This amendment eliminates future royalties to Alaunos and enhances Precigen's ability to develop and commercialize UltraCAR-T therapies. The UltraCAR-T platform aims to deliver personalized treatments with overnight manufacturing, potentially transforming cancer therapy. The company is progressing its clinical programs for various cancers while planning a business and clinical update call on April 4, 2023.
Precigen, Inc. (NASDAQ: PGEN) announced the first patient dosing in the Phase 1/1b study of PRGN-3007, an investigational UltraCAR-T therapy targeting advanced ROR1-positive hematological and solid tumors. This innovative therapy integrates PD-1 checkpoint inhibition and aims to simplify and reduce costs associated with current treatments by eliminating the need for systemic checkpoint inhibitors. The clinical trial will enroll patients with chronic lymphocytic leukemia, mantle cell lymphoma, acute lymphoblastic leukemia, and diffuse large B-cell lymphoma. With over 100,000 patients diagnosed in the U.S., E.U., and Japan in 2023, this development marks a significant milestone for Precigen's advanced cancer therapies.
Precigen, Inc. (Nasdaq: PGEN) announced that its President and CEO, Helen Sabzevari, PhD, will join a virtual fireside chat on April 4, 2023, from 10:45 AM to 11:15 AM ET at Cantor's "The Future of Oncology" Virtual Symposium.
Specializing in innovative gene and cell therapies, Precigen aims to address urgent healthcare challenges in immuno-oncology, autoimmune disorders, and infectious diseases. Investors can find more details in the Events & Presentations section on Precigen's website.
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