Welcome to our dedicated page for Precigen news (Ticker: PGEN), a resource for investors and traders seeking the latest updates and insights on Precigen stock.
Precigen, Inc. (Nasdaq: PGEN) is a biopharmaceutical company focused on precision medicines, and its news flow reflects the transition from a clinical-stage organization to a commercial-stage company. Recent announcements highlight full FDA approval and commercial launch of PAPZIMEOS (zopapogene imadenovec-drba), which the company describes as the first and only FDA-approved therapy for adults with recurrent respiratory papillomatosis (RRP). News items detail how PAPZIMEOS was discovered and designed using Precigen’s AdenoVerse platform and how it is being prescribed nationwide in the United States.
Investors and observers following PGEN news will see updates on PAPZIMEOS commercialization, including patient hub enrollment, payer coverage across private health plans and government programs, manufacturing and supply chain arrangements, and engagement with major medical centers and community practices. The company also issues news on long-term clinical data for PAPZIMEOS, emphasizing durable complete responses, reductions in surgery rates, and safety outcomes presented at medical meetings and in peer-reviewed publications.
Beyond PAPZIMEOS, Precigen’s news coverage includes pipeline developments such as progress in Phase 2 trials for PRGN-2009 in HPV-associated cancers and updates on PRGN-3006, an investigational UltraCAR-T therapy for acute myeloid leukemia and myelodysplastic syndromes. Financial results releases and related press statements provide context on capital resources, non-dilutive financing arrangements, preferred stock transactions, and the company’s expectations regarding funding operations through a projected cash flow break-even point.
Visitors to the PGEN news page can expect regular disclosures on regulatory milestones, conference presentations, investor webcasts, and business updates that illustrate how Precigen is advancing its precision medicine strategy and commercial execution around PAPZIMEOS and its broader pipeline.
Precigen, Inc. (NASDAQ: PGEN) announced the first patient dosing in the Phase 1/1b study of PRGN-3007, an investigational UltraCAR-T therapy targeting advanced ROR1-positive hematological and solid tumors. This innovative therapy integrates PD-1 checkpoint inhibition and aims to simplify and reduce costs associated with current treatments by eliminating the need for systemic checkpoint inhibitors. The clinical trial will enroll patients with chronic lymphocytic leukemia, mantle cell lymphoma, acute lymphoblastic leukemia, and diffuse large B-cell lymphoma. With over 100,000 patients diagnosed in the U.S., E.U., and Japan in 2023, this development marks a significant milestone for Precigen's advanced cancer therapies.
Precigen, Inc. (Nasdaq: PGEN) announced that its President and CEO, Helen Sabzevari, PhD, will join a virtual fireside chat on April 4, 2023, from 10:45 AM to 11:15 AM ET at Cantor's "The Future of Oncology" Virtual Symposium.
Specializing in innovative gene and cell therapies, Precigen aims to address urgent healthcare challenges in immuno-oncology, autoimmune disorders, and infectious diseases. Investors can find more details in the Events & Presentations section on Precigen's website.
Precigen (Nasdaq: PGEN) reported significant clinical advancements in its UltraCAR-T® and AdenoVerse™ therapies for 2022. The company presented positive results for PRGN-2012, showing a 50% complete response rate in recurrent respiratory papillomatosis, and PRGN-3006 demonstrated a 27% objective response rate in relapsed AML patients. Precigen strengthened its balance sheet through a non-health subsidiary divesture and raised approximately $73 million in a stock offering. As of December 31, 2022, it maintained $99.7 million in cash and equivalents, providing a healthy cash runway into late 2024. Total revenues increased by 89% year-over-year, but losses from continuing operations were $79.8 million.
Precigen, Inc. (Nasdaq: PGEN) has successfully closed its underwritten public offering of 42,857,143 shares of common stock at a price of $1.75 per share. The offering generated gross proceeds of approximately $75.0 million before expenses. J.P. Morgan Securities LLC and Cantor Fitzgerald & Co. were the lead managers. The offering was made under an effective shelf registration statement filed with the SEC. Precigen focuses on advancing gene and cell therapies targeting various diseases, including cancer and autoimmune disorders, emphasizing the development of affordable biotherapeutics.
Precigen, Inc. (PGEN) has announced the pricing of a public offering of 42,857,143 shares of its common stock at $1.75 per share, targeting gross proceeds of approximately $75.0 million. The underwriters have a 30-day option to purchase an additional 6,428,571 shares. The offering is expected to close on January 27, 2023, subject to customary conditions. Proceeds will fund the development of clinical and preclinical candidates and general corporate purposes. The offering is made under a shelf registration statement effective since July 2, 2020.
Precigen, Inc. (Nasdaq: PGEN) has announced a public offering of $75 million of its common stock, with an additional $11.25 million available through underwriters' options. This offering, subject to market conditions, involves all shares being sold by the company. J.P. Morgan Securities LLC is the lead manager for this offering, with support from Cantor Fitzgerald & Co. and others. The offering is made under a shelf registration statement that became effective on July 2, 2020. Precigen's mission involves advancing gene and cell therapies for urgent diseases. The company emphasizes that the completion of the offering is uncertain.
Precigen (NASDAQ: PGEN) reported positive Phase 1 clinical trial results for its investigational PRGN-2012 AdenoVerse immunotherapy in patients with recurrent respiratory papillomatosis (RRP). Key findings include:
- 50% of patients achieved Complete Response, requiring no surgeries within 12 months post-treatment.
- Median surgeries decreased from 6.5 to 0.5 for treated patients.
- 32 patients are currently enrolled in Phase 2, with future regulatory discussions pending.
These results suggest a significant reduction in surgical intervention and a potential shift in treatment paradigms for RRP.
Precigen (PGEN) presented significant clinical progress at the 41st Annual J.P. Morgan Healthcare Conference. The company highlighted advancements in its UltraCAR-T and AdenoVerse programs throughout 2022. Key updates include ongoing Phase 2 trials for PRGN-2012, aimed at treating recurrent respiratory papillomatosis, and positive Phase 1 data for PRGN-3006 in acute myeloid leukemia. Precigen plans to host an R&D Day on January 24, 2023, to discuss safety and efficacy data from its ongoing studies.
Precigen, a biopharmaceutical company, is set to host an investigator-led R&D event on January 24, 2023, at 4:30 PM ET. The focus will be on the first-in-class PRGN-2012 AdenoVerse Immunotherapy targeting recurrent respiratory papillomatosis (RRP). The event will present complete Phase 1 clinical trial safety and efficacy data, featuring insights from key officials including Clint T. Allen, MD, and Helen Sabzevari, PhD. The company aims to demonstrate the potential of PRGN-2012 for the underserved RRP patient population.
Precigen, Inc. (Nasdaq: PGEN), a biopharmaceutical company focusing on gene and cell therapies, announced that its CEO, Helen Sabzevari, PhD, will present a corporate and clinical overview at the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023, at 3:45 PM PT in San Francisco, California. Participants can register to view the event on Precigen's website under the Events & Presentations section. Precigen is advancing therapies in immuno-oncology and other critical areas, working towards innovative solutions in biotherapeutics.