Welcome to our dedicated page for Phio Pharmaceuticals news (Ticker: PHIO), a resource for investors and traders seeking the latest updates and insights on Phio Pharmaceuticals stock.
Phio Pharmaceuticals Corp (NASDAQ: PHIO) is a clinical-stage biotechnology pioneer developing next-generation immuno-oncology therapies using its proprietary INTASYL® RNAi platform. This page provides centralized access to official press releases, clinical trial updates, and strategic partnership announcements related to PHIO's innovative approach to enhancing immune cell function against cancer.
Investors and researchers will find timely updates on PHIO's progress in silencing immune checkpoint targets like PD-1 and TIGIT through its self-delivering siRNA technology. The resource covers key developments including clinical trial milestones, collaborative research findings, and regulatory advancements for therapies like lead candidate PH-762.
Content spans multiple categories essential for tracking biopharmaceutical innovation: clinical trial results, research collaborations with institutions like Gustave Roussy, intellectual property updates, and technology licensing agreements. Each update is sourced directly from company disclosures to ensure reliability.
Bookmark this page for streamlined monitoring of PHIO's advancements in RNAi-based cancer therapeutics. Check regularly for new developments in their mission to overcome tumor-induced immunosuppression through precision gene silencing.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) has opened enrollment for its first-in-human clinical trial of PH-762, aimed at treating advanced melanoma. The study will assess safety and anti-tumor activity, with initial data expected in Q1 2023. Phio is also finalizing IND-enabling studies for PH-894, targeting patients unresponsive to PD-1 therapy. For Q1 2022, the company reported a net loss of $2.6 million, down from $3.4 million in Q1 2021, due to reduced R&D expenses. Cash reserves stand at $20.5 million, sufficient to fund operations into Q2 2023.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced the departure of Dr. Gerrit Dispersyn as President and CEO effective May 5, 2022. Dispersyn, who joined in 2017, played a key role in transitioning the company towards immuno-oncology therapeutics, particularly through the INTASYL™ platform targeting cutaneous melanoma. Following his departure, Dr. Geert Cauwenbergh, the former CEO, will serve as Principal Executive Officer until a new CEO is appointed. This leadership change comes as the company progresses in developing its RNAi therapeutic platform.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced its participation in the 2022 American Society of Clinical Oncology (ASCO) annual meeting, set for June 3-7, 2022, in Chicago, IL. The company will present a trial-in-progress poster titled "A First-in-Human, Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-Tumor Activity of Neoadjuvant Use of PH-762 Administered Intratumorally in Subjects with Advanced Melanoma". The poster's author is Professor Caroline Robert, and the presentation is scheduled for June 6, 2022, from 1:15 to 4:15 p.m. Central Time.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced the presentation of new preclinical data on PH-894, an innovative therapeutic based on their proprietary self-delivering RNAi platform, at the ASGCT 25th Annual Meeting from May 16-19, 2022. This research focuses on improving the phenotype of HER2-CAR-T cells during expansion. The poster session is scheduled for May 16, 2022, from 5:30 PM - 6:30 PM EDT at the Walter E. Washington Convention Center in Washington, D.C., highlighting the company's advancements in immuno-oncology therapeutics.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) appointed Patricia A. Bradford as an independent director to its Board. Bradford, with over 40 years of HR and financial experience, previously held senior roles at Unisys Corporation and Deloitte. Chairman Robert Bitterman expressed confidence in her ability to contribute significantly during a pivotal period as the first INTASYL therapeutic compounds enter clinical trials. Bradford also emphasizes her excitement to work on advancing the company’s portfolio of immuno-oncology therapies aimed at cancer treatment.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) has commenced patient enrollment in the Phase 1b clinical trial for PH-762, aimed at treating advanced melanoma. This trial represents a significant milestone, being the first clinical study of PH-762, which targets PD-1 to enhance immune response against cancer cells. Conducted at the Gustave Roussy Institute, it will assess the safety, tolerability, and anti-tumor activity of PH-762. The study is crucial as there are currently no approved neoadjuvant treatments for advanced melanoma, and preclinical data suggest promising efficacy.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced that its in vivo data on PH-762, a self-delivering RNAi therapeutic, indicating tumor clearance, will be presented at the Society for Immunotherapy of Cancer (SITC) Workshop on April 21-22, 2022, in San Diego. The presentation is titled 'Locally administered immunotherapy self-delivering RNAi PH-762 results in abscopal clearance of untreated distal tumors.' The session is scheduled for April 21 from 5:20 p.m. to 6:20 p.m. PT.
This highlights Phio's commitment to developing innovative immuno-oncology treatments.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) announced positive preclinical data for PH-894, a self-delivering RNAi compound targeting BRD4. The data, to be presented at the AACR Annual Meeting 2022, show that PH-894 inhibited tumor growth in PD-1 responsive and insensitive models and enhanced the efficacy of anti-PD-1 antibody therapy on both treated and untreated distal tumors. The results highlight PH-894's potential as a standalone therapy and in combination with anti-PD-1 treatment, addressing a significant medical need for patients unresponsive to current therapies.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced its transition into a clinical-stage company with the initiation of its first clinical study for PH-762 targeting advanced melanoma. The company reported a net loss of $13.3 million for the year ended December 31, 2021, up from $8.8 million in 2020. The company holds $24.1 million in cash, sufficient to fund operations into the second quarter of 2023. Upcoming milestones include starting patient enrollment for PH-762 and new data presentations related to its pipeline in 2022.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced the upcoming presentation of new preclinical data on its RNAi compound PH-894, targeting BRD4, at the AACR Annual Meeting 2022 in New Orleans from April 8-13, 2022. The poster session will discuss PH-894's potential to provide abscopal efficacy toward untreated distal tumors and enhance systemic anti-PD-1 antibody therapy effectiveness. The presentation, led by Benjamin Cuiffo and accessible in person and virtually, is scheduled for April 13, 2022, from 9:00 AM to 12:30 PM.
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