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Polyrizon to Explore Revenue-Generating Investment Opportunities in High-Growth Sectors, Leveraging Strong Cash Position and Debt-Free Balance Sheet

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Polyrizon (Nasdaq: PLRZ) said on January 13, 2026 that its board authorized exploring strategic investments in revenue-generating operating companies in defense, aviation, and artificial intelligence (AI). The company emphasized it remains fully committed to advancing its core intranasal medical pipeline, including PL-14, PL-16 and the Trap & Target intranasal delivery platform.

The board said it will leverage a reported strong cash position and a debt-free balance sheet to pursue selective investments intended to generate near-term revenue while maintaining focus on clinical and regulatory progress.

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News Market Reaction

+0.66%
11 alerts
+0.66% News Effect
+16.9% Peak in 30 hr 19 min
+$159K Valuation Impact
$24M Market Cap
0.6x Rel. Volume

On the day this news was published, PLRZ gained 0.66%, reflecting a mild positive market reaction. Argus tracked a peak move of +16.9% during that session. Our momentum scanner triggered 11 alerts that day, indicating notable trading interest and price volatility. This price movement added approximately $159K to the company's valuation, bringing the market cap to $24M at that time.

Data tracked by StockTitan Argus on the day of publication.

Market Reality Check

Price: $13.85 Vol: Volume 70,884 is about 0....
low vol
$13.85 Last Close
Volume Volume 70,884 is about 0.41x the 20-day average, indicating relatively light trading versus recent norms. low
Technical Shares at $13.74 are trading below the 200-day MA of $110.25 and remain far under the 52-week high of $2,550.

Peers on Argus

PLRZ gained 7.43% while close peers were mixed: ADTX up 3.17%, SXTP up 4.39%, bu...
1 Down

PLRZ gained 7.43% while close peers were mixed: ADTX up 3.17%, SXTP up 4.39%, but TTNP, ENSC, and SILO declined between -0.95% and -6.69%. Momentum scanner only flagged ARTL moving down, reinforcing a stock-specific move.

Historical Context

5 past events · Latest: Jan 08 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Jan 08 Branding milestone Positive +8.4% Completion of NASARIX™ branding for PL-14 using proprietary intranasal spray technology.
Jan 05 Pre-clinical data Positive -0.8% PL-14 showed strong in‑vitro allergen-blocking versus HPMC in permeability model.
Jan 02 Product positioning Positive +50.2% Flu-season update highlighting PL-16 viral blocker as complementary protection option.
Dec 29 Strategic investments Positive -1.4% Board authorized exploration of revenue-generating real assets alongside core pipeline.
Dec 19 Regulatory step Positive -6.7% Submission of Pre-RFD to FDA for PL-16 viral blocker intranasal product.
Pattern Detected

Recent news has generally been positive, but price reactions have been inconsistent, with more instances of selling or muted response than sustained follow-through on good milestones.

Recent Company History

Over the last few weeks, Polyrizon reported several developmental and strategic steps. On Dec 19, 2025, it submitted a Pre-RFD to the FDA for PL-16, followed by a broader flu-season positioning update on Jan 02, 2026. Branding progress for PL-14 as NASARIX™ was announced on Jan 08. The board also previously authorized exploration of revenue-generating real assets on Dec 29, 2025. Today’s announcement extends that capital-allocation theme into operating companies in sectors such as defense, aviation, and AI, while reiterating focus on the intranasal pipeline.

Regulatory & Risk Context

Active S-3 Shelf · $50,000,000
Shelf Active
Active S-3 Shelf Registration 2025-11-07
$50,000,000 registered capacity

An effective Form F-3 shelf registration would allow Polyrizon to offer up to $50,000,000 of ordinary shares, warrants, or units over time, via methods such as at-the-market offerings or negotiated deals, with proceeds earmarked for general purposes and potential strategic opportunities.

Market Pulse Summary

This announcement details Polyrizon’s plan to deploy its strong cash position and debt-free balance ...
Analysis

This announcement details Polyrizon’s plan to deploy its strong cash position and debt-free balance sheet into revenue-generating operating companies in sectors such as defense, aviation, and AI, while maintaining focus on PL-14, PL-16, and its Trap & Target intranasal platform. Investors may track how these initiatives complement prior branding, pre-clinical, and regulatory steps and monitor any future use of the $50,000,000 shelf registration for strategic or funding purposes.

Key Terms

intranasal, intranasal drug delivery
2 terms
intranasal medical
"a pre-clinical-stage biotechnology company developing intranasal protective solutions"
Administration or delivery of a drug or vaccine through the nose, typically via a spray or drops that are absorbed by the nasal tissues. For investors, intranasal products can matter because they often offer easier, needle-free use, faster onset of effect, and potential cost or compliance advantages that can widen a product’s market and affect regulatory review, manufacturing complexity, and commercial prospects — similar to how a convenient app can outsell a clunky desktop program.
intranasal drug delivery medical
"the Trap & Target platform for intranasal drug delivery"
Intranasal drug delivery is a method of giving medication through the nose so the active ingredient is absorbed across the nasal lining into the bloodstream or, in some cases, more directly into the brain. For investors, it matters because this route can speed onset, avoid breakdown in the digestive system, and enable treatments that would be hard or costly by injection or pills, potentially shortening development time, cutting costs, and opening new market opportunities.

AI-generated analysis. Not financial advice.

Company Remains Fully Committed to Advancing Its Core Intranasal Medical Pipeline, alongside examining new opportunities including in fields of aviation, AI and defense

Raanana, Israel, Jan. 13, 2026 (GLOBE NEWSWIRE) -- Polyrizon Ltd. Polyrizon Ltd. (Nasdaq: PLRZ) (“Polyrizon” or the “Company”), a pre-clinical-stage biotechnology company developing intranasal protective solutions, recently announced that its Board of Directors has authorized the exploration of strategic investment opportunities in select revenue-generating assets.

Polyrizon is focusing its initial efforts on operating companies in high-potential sectors, including defense, aviation, and artificial intelligence (AI).

The Company remains fully committed to its core medical device activities, continuing to advance product development, preclinical and clinical studies, and regulatory progress – including products such as PL-14 (allergy blocker), PL-16 (viral blocker), and the Trap & Target platform for intranasal drug delivery.

In parallel, leveraging the Company’s strong cash position and debt-free balance sheet, the Company’s Board of Directors has approved pursing selective investments that are expected to generate near-term revenues, enhance financial stability and create additional value for shareholders. This strategic initiative aims to efficiently utilize the Company’s resources to accelerate growth and deliver long-term shareholder value, while maintaining full focus on the primary medical pipeline.

About Polyrizon

Polyrizon is a development stage biotech company specializing in the development of innovative medical device hydrogels delivered in the form of nasal sprays, which form a thin hydrogel-based shield containment barrier in the nasal cavity that can provide a barrier against viruses and allergens from contacting the nasal epithelial tissue. Polyrizon’s proprietary Capture and Contain TM, or C&C, hydrogel technology, comprised of a mixture of naturally occurring building blocks, is delivered in the form of nasal sprays, and potentially functions as a “biological mask” with a thin shield containment barrier in the nasal cavity. Polyrizon are further developing certain aspects of our C&C hydrogel technology such as the bioadhesion and prolonged retention at the nasal deposition site for intranasal delivery of drugs. Polyrizon refers to its additional technology, which is in an earlier stage of pre-clinical development, that is focused on nasal delivery of active pharmaceutical ingredients, or APIs, as Trap and Target ™, or T&T. For more information, please visit https://polyrizon-biotech.com.

Forward Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and other securities laws. Words such as “expects,” “anticipates,” “intends,” “plans,” “believes,” “seeks,” “estimates” and similar expressions or variations of such words are intended to identify forward-looking statements. For example, the Company is using forward-looking statements when it discusses exploring investments in assets that are expected to generate revenues, focusing its initial efforts on operating companies in high-potential sectors, including defense, aviation, and artificial intelligence, pursing selective investments that are expected to generate near-term revenues, enhance financial stability and create additional value for shareholders and accelerating growth and delivering long-term shareholder value, while maintaining full focus on the primary medical pipeline. Forward-looking statements are not historical facts, and are based upon management’s current expectations, beliefs and projections, many of which, by their nature, are inherently uncertain. Such expectations, beliefs and projections are expressed in good faith. However, there can be no assurance that management’s expectations, beliefs and projections will be achieved, and actual results may differ materially from what is expressed in or indicated by the forward-looking statements. Forward-looking statements are subject to risks and uncertainties that could cause actual performance or results to differ materially from those expressed in the forward-looking statements. For a more detailed description of the risks and uncertainties affecting the Company, reference is made to the Company’s reports filed from time to time with the Securities and Exchange Commission (“SEC”), including, but not limited to, the risks detailed in the Company’s annual report filed with the SEC on March 11, 2025 and subsequent filings with the SEC. Forward-looking statements speak only as of the date the statements are made. The Company assumes no obligation to update forward-looking statements to reflect actual results, subsequent events or circumstances, changes in assumptions or changes in other factors affecting forward-looking information except to the extent required by applicable securities laws. If the Company does update one or more forward-looking statements, no inference should be drawn that the Company will make additional updates with respect thereto or with respect to other forward-looking statements. References and links to websites have been provided as a convenience, and the information contained on such websites is not incorporated by reference into this press release. Polyrizon is not responsible for the contents of third-party websites.

Contacts:

Michal Efraty

Investor Relations

IR@polyrizon-biotech.com


FAQ

What did Polyrizon (PLRZ) announce on January 13, 2026 about new investments?

Polyrizon's board authorized exploring selective investments in operating companies in defense, aviation, and AI to seek near-term revenue.

Will Polyrizon (PLRZ) stop advancing its medical pipeline after the January 13, 2026 announcement?

No; the company said it remains fully committed to advancing product development, preclinical and clinical studies, and regulatory progress.

Which pipeline programs did Polyrizon (PLRZ) highlight on January 13, 2026?

Polyrizon highlighted intranasal programs PL-14 (allergy blocker), PL-16 (viral blocker), and the Trap & Target drug delivery platform.

How will Polyrizon (PLRZ) fund the new investment initiative announced January 13, 2026?

The company said it plans to leverage its strong cash position and debt-free balance sheet to pursue selective investments.

What is the intended investor impact of Polyrizon's (PLRZ) January 13, 2026 strategic initiative?

The board expects selective investments to generate near-term revenues, enhance financial stability, and create additional shareholder value while keeping focus on the medical pipeline.
Polyrizon Ltd

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Biotechnology
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Israel
Ra'anana