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Plus Therapeutics Announces Scientific Presentations and Sponsored Symposium at 2026 SNO/ASCO CNS Metastases Conference

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Plus Therapeutics (Nasdaq: PSTV) will feature two scientific posters and a sponsored symposium at the 2026 SNO/ASCO CNS Metastases Conference, held August 13–15, 2026, in Boston. The presentations highlight the Company’s ReSPECT-LM clinical development program with rhenium obisbemeda and its CNSide® cerebrospinal fluid diagnostic platform.

Plus Therapeutics and wholly owned subsidiary CNSide Diagnostics will also host a one-hour symposium on August 13 titled “Redefining the Management of Leptomeningeal Metastases,” and plan to introduce the new Cerenome brand and expanded CNS cancer focus. Posters will later be posted on the Company’s website.

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Positive

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Negative

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Market Context

PSTV had an active S-3/A shelf dated June 5, 2026, with 0 recorded uses. Against that financing cont...
Analysis

PSTV had an active S-3/A shelf dated June 5, 2026, with 0 recorded uses. Against that financing context, the conference announcement adds scheduled visibility without reported clinical results; short positioning was moderate.

Key Figures

Posters: 2 posters Conference dates: August 13–15, 2026 Poster presentation time: 7:15–9:00 PM ET +2 more
5 metrics
Posters 2 posters 2026 SNO/ASCO CNS Metastases Conference
Conference dates August 13–15, 2026 SNO/ASCO CNS Metastases Conference
Poster presentation time 7:15–9:00 PM ET Thursday, August 13, 2026
Symposium time 6:15–7:15 PM ET Thursday, August 13, 2026
Future care horizon 2030 Symposium discussion topic

Historical Context

5 past events · Latest: Jul 21 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jul 21 Coverage agreement Positive +2.4% Medical Mutual agreement expanded CNSide contracted coverage across Ohio and Kentucky.
Jul 16 Platform partnership Positive -4.4% Genomic Testing Cooperative collaboration added next-generation sequencing to the CNSide assay platform.
Jul 14 Guideline update Positive +2.6% Updated NCCN guidance continued endorsing CSF analysis for leptomeningeal metastases monitoring.
Jun 30 Rebranding update Positive +1.9% Company announced Cerenome rebranding, planned ticker change, and affirmed 2026 milestones.
Jun 25 Coverage agreement Positive +7.6% Elevance Health agreement added national CNSide coverage for approximately 45.4 million people.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

PSTV's recent news reactions were generally positive, although its July 16 partnership announcement diverged with a 4.41% decline.

Key Terms

pharmacokinetic, pharmacodynamic, cerebrospinal fluid, leptomeningeal metastases, +1 more
5 terms
pharmacokinetic medical
"Pharmacokinetic and Pharmacodynamic Assessment of Rhenium Obisbemeda"
Pharmacokinetic describes how a drug moves through and leaves the body — how it is absorbed, spread to tissues, broken down and excreted — like tracking a package from pickup to delivery and disposal. For investors, these properties determine effective dose, safety risks, how often a medicine must be taken, and how reliably it works, which in turn influence clinical trial success, regulatory approval chances, production complexity and a drug’s commercial value.
pharmacodynamic medical
"Pharmacokinetic and Pharmacodynamic Assessment of Rhenium Obisbemeda"
Pharmacodynamic describes how a drug acts on the body — the biological effects it produces, how strong those effects are, and how long they last. For investors, pharmacodynamic data show whether a treatment actually works and at what dose, shaping expectations about a drug’s safety, effectiveness, regulatory success and market potential; think of it like testing how well a key turns a lock and whether it reliably opens the door.
cerebrospinal fluid medical
"CNSide® cerebrospinal fluid (“CSF”) diagnostic platform"
A clear fluid that surrounds and cushions the brain and spinal cord, acting like a protective bath and cleanup system that removes waste and helps circulate nutrients. For investors, cerebrospinal fluid matters because it is a common source of diagnostic markers and a route for delivering or testing neurological drugs; changes in its composition can signal disease or affect a therapy’s development, approval prospects, and market value.
leptomeningeal metastases medical
"management of Leptomeningeal Metastases"
Leptomeningeal metastases occur when cancer cells spread to the thin layers of tissue covering the brain and spinal cord, similar to how weeds can invade the surface layer of soil. This condition often indicates advanced disease and can lead to serious neurological problems. For investors, the presence of such metastases may signal challenges in treatment options and can impact the outlook for related healthcare companies or research developments.
biomarkers medical
"The expanding role of CSF-based biomarkers in precision diagnostics"
Biomarkers are measurable indicators found in the body, such as substances in blood or tissues, that reveal information about health or disease. For investors, they can signal how well a medical treatment is working or whether a disease is developing, helping to assess the potential success or risks of healthcare companies or innovations. Think of biomarkers as biological signals that provide clues about a person’s health status.

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Posters will highlight research across the Company’s REYOBIQ™ clinical development program and CNSide® cerebrospinal fluid diagnostic platform

HOUSTON, July 28, 2026 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq: PSTV) (the “Company”), a healthcare company developing and commercializing targeted therapeutics and diagnostics for central nervous system (“CNS”) cancers, today announced two posters highlighting its ReSPECT-LM clinical development program and CNSide® cerebrospinal fluid (“CSF”) diagnostic platform will be presented at the 2026 Society for Neuro-Oncology/American Society of Clinical Oncology (“SNO/ASCO”) CNS Metastases Conference, being held August 13–15, 2026, in Boston, Massachusetts.

The Company and its wholly owned subsidiary, CNSide Diagnostics, LLC, will also host a sponsored symposium titled “Redefining the Management of Leptomeningeal Metastases: Integrating Diagnostics, Molecular Insights, and Emerging Therapies” on Thursday evening, August 13, 2026.

“At this year’s SNO/ASCO CNS Metastases Conference, we intend to show how Plus can help caregivers improve the detection, characterization, treatment and monitoring of patients with CNS metastases,” said Marc H. Hedrick, M.D., Plus Therapeutics’ President and Chief Executive Officer. “Furthermore, we are excited to formally introduce Cerenome, Plus’ new identity, as well as new branding around our expanded focus on CNS cancer at the meeting.”

Details of the poster presentations are as follows:

ReSPECT-LM Poster Presentation

Title: ReSPECT-LM: Pharmacokinetic and Pharmacodynamic Assessment of Rhenium Obisbemeda in Leptomeningeal Metastases with Emerging Data from Repeated Dosing (ReSPECT-LMM)
Presenter: Andrew Brenner, MD, PhD, University of Texas Health Science Center at San Antonio
Date and Time: Thursday, August 13, 2026, 7:15-9:00 PM ET
Location: America Ballroom at the Westin Copley Place

CNSide Poster Presentation

Title: Economic impact of earlier detection and therapeutic management of leptomeningeal metastases using CNSide®: a cost-of-care analysis
Presenter: Kelly Kreitzburg Ondrasek, PhD, Medical Science Liaison at CNSide Diagnostics
Date and Time: Thursday, August 13, 2026, 7:15-9:00 PM ET
Location: America Ballroom at the Westin Copley Place

Sponsored Symposium

Title: Redefining the Management of Leptomeningeal Metastases: Integrating Diagnostics, Molecular Insights, and Emerging Therapies
Date and Time: Thursday, August 13, 2026, from 6:15 PM to 7:15 PM ET

The symposium will bring together leading key opinion leaders to discuss the evolving management of leptomeningeal metastases, including:

  • The current treatment landscape, unmet needs and clinical challenges
  • The expanding role of CSF-based biomarkers in precision diagnostics
  • Emerging therapeutic strategies and future directions for treatment
  • The role of data analytics, AI and precision medicine in patient management
  • What precision care could look like in 2030

The symposium is presented by Plus Therapeutics and CNSide Diagnostics. Additional symposium information and a form to request a recording of the presentation are available here.

Following the presentation at the conference, the posters will be available on the Publications page of the Company’s website.

About REYOBIQ™ (Rhenium-186 Obisbemeda)

REYOBIQ™, or rhenium-186 obisbemeda, is a novel injectable radiotherapy specifically formulated to deliver direct, targeted, high-dose radiation to CNS tumors while potentially limiting radiation exposure to healthy tissue. REYOBIQ is being evaluated for the treatment of recurrent glioblastoma, leptomeningeal metastases and pediatric brain cancer through the ReSPECT clinical development program.

About CNSide Diagnostics, LLC

CNSide Diagnostics, LLC, a wholly owned subsidiary of Plus Therapeutics, Inc., develops and commercializes proprietary laboratory-developed tests such as CNSide®, which is designed to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The CNSide® CSF Assay Platform enables quantitative analysis of cerebrospinal fluid to inform and improve the management of patients with leptomeningeal metastases. For more information, please visit www.cnside-dx.com.

About Plus Therapeutics

Plus Therapeutics, Inc. (NASDAQ: PSTV) is a clinical-stage healthcare company advancing an integrated approach to central nervous system (“CNS”) cancers through precision therapeutics, molecular diagnostics and data-driven technologies. The Company's lead therapeutic platform, REYOBIQ™ (rhenium Re186 obisbemeda), is being developed for the treatment of leptomeningeal metastases, recurrent glioblastoma and pediatric brain cancers. Its CNSide® cerebrospinal fluid assay platform is designed to provide diagnostic and disease monitoring information to support the management of patients with CNS cancers. Together with its growing data and artificial intelligence capabilities, Plus Therapeutics is building an integrated CNS oncology platform intended to improve clinical decision-making, accelerate therapeutic development and advance personalized care for patients with CNS cancers.

Effective August 3, 2026, Plus Therapeutics will change its corporate name to Cerenome, Inc. and begin trading under the Nasdaq ticker symbol CNSY. Until that date, the Company will continue to operate as Plus Therapeutics and trade under the ticker symbol PSTV.

For more information, please visit www.plustherapeutics.com. Beginning August 3, 2026, additional information will be available at www.cerenome.com.

Forward-Looking Statements

This press release contains statements that may be deemed "forward-looking statements" within the meaning of U.S. securities laws, including statements regarding clinical trials, expected operations and upcoming developments. All statements in this press release other than statements of historical fact are forward-looking statements. These forward-looking statements may be identified by future verbs, as well as terms such as "expect," "potential," "anticipating," "planning" and similar expressions or the negatives thereof. Such statements are based upon certain assumptions and assessments made by management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate. These statements include, without limitation, statements regarding the potential market for the CNSide CSF Assay, the timing in which the CNSide CSF Assay is commercially launched and commercialization is expanded, revenue and corporate profitability expectations including support reimbursements and payments for the CNSide CSF Assay, the development and utility of the CNSide CSF Assay and expectations as to the Company's future performance, including the next steps in developing the Company's product candidates.

Investor Contact
CORE IR
investor@plustherapeutics.com


FAQ

What will Plus Therapeutics (Nasdaq: PSTV) present at the 2026 SNO/ASCO CNS Metastases Conference?

Plus Therapeutics will present two posters and host a sponsored symposium focused on leptomeningeal metastases. According to Plus Therapeutics, the work highlights its ReSPECT-LM rhenium obisbemeda program and CNSide® cerebrospinal fluid diagnostics, along with its broader central nervous system cancer strategy.

When and where is the ReSPECT-LM poster by Plus Therapeutics presented at SNO/ASCO CNS Metastases 2026?

The ReSPECT-LM poster is scheduled for August 13, 2026, from 7:15–9:00 PM ET in the America Ballroom at the Westin Copley Place. According to Plus Therapeutics, it covers pharmacokinetic and pharmacodynamic assessment with emerging repeated-dosing data.

What is the focus of the CNSide cost-of-care poster from Plus Therapeutics at SNO/ASCO 2026?

The CNSide poster evaluates the economic impact of earlier detection and therapeutic management of leptomeningeal metastases using CNSide®. According to Plus Therapeutics, it presents a cost-of-care analysis and is scheduled August 13, 2026, 7:15–9:00 PM ET in the America Ballroom.

What topics will Plus Therapeutics’ sponsored symposium on leptomeningeal metastases cover in August 2026?

The symposium will discuss current treatment challenges, CSF-based biomarkers, emerging therapies, and roles of data analytics and AI. According to Plus Therapeutics, it runs August 13, 2026, 6:15–7:15 PM ET and explores what precision care could look like by 2030.

How can investors or clinicians access Plus Therapeutics’ SNO/ASCO CNS Metastases 2026 materials?

Conference posters will be available on Plus Therapeutics’ Publications webpage after the meeting. According to Plus Therapeutics, additional symposium information and a form to request a recording of the presentation are also being made available through the Company’s symposium information channel.

What branding update is Plus Therapeutics (PSTV) planning to share at the 2026 SNO/ASCO CNS Metastases Conference?

Plus Therapeutics plans to formally introduce Cerenome, its new corporate identity, and updated CNS cancer branding. According to Plus Therapeutics, this rebranding will be showcased during the SNO/ASCO CNS Metastases meeting alongside its therapeutic and diagnostic program updates.