Welcome to our dedicated page for Protagonist Ther news (Ticker: PTGX), a resource for investors and traders seeking the latest updates and insights on Protagonist Ther stock.
News about Protagonist Therapeutics, Inc. (NASDAQ: PTGX) centers on its progress as a discovery-through-late-stage development biopharmaceutical company advancing peptide-based drug candidates. Company announcements frequently highlight clinical and regulatory milestones for its lead investigational therapies, icotrokinra and rusfertide, as well as updates from its broader pipeline and collaborations.
Investors following PTGX news will see regular coverage of icotrokinra, a first-in-class investigational targeted oral peptide that selectively blocks the IL-23 receptor. Press releases describe data from Phase 3 ICONIC studies in moderate-to-severe plaque psoriasis, including ICONIC-LEAD, ICONIC-TOTAL, and ICONIC-ADVANCE 1 and 2, as well as the Phase 2b ANTHEM-UC trial in ulcerative colitis. News items also report on regulatory submissions, such as the New Drug Application to the U.S. FDA and an application to the European Medicines Agency for plaque psoriasis.
Coverage of rusfertide focuses on its development for polycythemia vera in collaboration with Takeda. News releases describe Phase 3 VERIFY study results, long-term extension data from THRIVE, and the submission of a New Drug Application to the FDA for adults with polycythemia vera. These updates often include details on hematocrit control, phlebotomy requirements, patient-reported outcomes, and regulatory designations such as Breakthrough Therapy, Orphan Drug, and Fast Track status.
Additional PTGX news includes presentations at major medical and scientific conferences, such as the American Society of Hematology Annual Meeting, European Academy of Dermatology and Venereology Congress, American College of Gastroenterology meeting, and the J.P. Morgan Healthcare Conference. The company also issues periodic financial result and corporate update releases, which summarize recent clinical achievements, collaboration developments with Johnson & Johnson and Takeda, and progress in earlier-stage programs like PN-881, PN-477, and the oral hepcidin initiative.
For readers tracking PTGX, this news stream provides insight into Protagonist’s clinical data, regulatory interactions, partnership activities, and pipeline evolution as described in its own public communications.
Protagonist Therapeutics (Nasdaq: PTGX) completed an underwritten public offering of 5,476,189 shares of common stock at a public price of $21.00 per share, raising approximately $115.0 million in gross proceeds. This includes 714,285 shares sold due to the underwriters' full exercise of their 'green shoe' option. The shelf registration statement was filed with the SEC on December 10, 2020. J.P. Morgan, SVB Leerink, Piper Sandler, and BMO Capital Markets managed the offering.
Protagonist Therapeutics, Inc. (Nasdaq: PTGX) has priced an underwritten public offering of 4,761,904 shares of common stock at $21.00 each, targeting $100 million in gross proceeds before expenses. The offering will close around December 15, 2020, subject to customary conditions. The underwriters have a 30-day option to buy an additional 714,285 shares. Joint book-running managers include J.P. Morgan, SVB Leerink, Piper Sandler, and BMO Capital Markets. A registration statement was filed with the SEC on the same day as the announcement.
Protagonist Therapeutics, Inc. (Nasdaq: PTGX) announced a public offering of $100 million of its common stock, with the possibility of granting underwriters a 30-day option to purchase an additional 15%. The offering is subject to market conditions, and there is no guarantee on its completion or the size of the offering. J.P. Morgan, SVB Leerink, Piper Sandler, and BMO Capital Markets are the joint book-running managers. A shelf registration statement was filed with the SEC on December 10, 2020. Investors are advised to consult the SEC filings for detailed information.
Protagonist Therapeutics (Nasdaq:PTGX) released findings from a significant analysis on treatment patterns for polycythemia vera, indicating that existing therapies fail to adequately control hematocrit levels in most patients. Specifically, only 22% maintained levels below the recommended 45%, with nearly 49% experiencing levels exceeding 50% during the observation. The results highlight an unmet need for effective treatment options in this patient population, with a Phase 2 study of PTG-300 currently enrolling participants. These findings will be discussed at the ASH 2020 meeting.
Protagonist Therapeutics (Nasdaq: PTGX) announced promising Phase 2 study results for PTG-300, aimed at treating polycythemia vera (PV). The study showed that most of the 18 patients treated could eliminate therapeutic phlebotomies while maintaining hematocrit levels below 45%. Additionally, PTG-300 demonstrated the ability to reverse iron deficiency and reduce symptom burden over time. The treatment was well tolerated with minimal adverse effects. Protagonist plans to share these findings with regulatory authorities and expects to complete patient enrollment by mid-2021.
Protagonist Therapeutics announced that its candidate PTG-300 received FDA Fast Track designation for treating polycythemia vera, a rare blood disorder. This designation could expedite the development process, including more frequent FDA interactions. PTG-300 is a synthetic hepcidin mimetic shown to significantly reduce phlebotomy needs in ongoing Phase 2 trials, which are expected to complete enrollment by mid-2021. The FDA's Fast Track program aims to accelerate therapies addressing serious conditions and unmet medical needs.
Protagonist Therapeutics, Inc. (Nasdaq: PTGX) announced on December 1, 2020, the issuance of an inducement award to Michelle Landolfi, Ph.D., its new Vice President of Regulatory Affairs. The award includes an option to purchase 50,000 shares at an exercise price of $24.16, with a four-year vesting schedule. This grant follows Nasdaq Marketplace Rule 5635(c)(4) and was approved by the company's compensation committee. Protagonist specializes in developing peptide-based therapeutics for unmet medical needs, with ongoing projects for polycythemia vera and inflammatory bowel disease.
Protagonist Therapeutics (Nasdaq:PTGX) announced a conference call on December 9, 2020, at 8:30 a.m. EST to provide an R&D and corporate update. The management team will be joined by Dr. Andrew Kuykendall from Moffitt Cancer Center, who is involved in the PTG-300 Phase 2 study. Interested parties can join the call by dialing 1-844-515-9178 (U.S./Canada) or 1-614-999-9313 (international) and referencing conference ID 8794865. The call will also be available via webcast on the company's website.
Protagonist Therapeutics, Inc. (NASDAQ: PTGX) announced that its CEO, Dinesh V. Patel, Ph.D., will participate in a fireside chat at the virtual Piper Sandler 32nd Annual Healthcare Conference from November 30 to December 3, 2020. Registered attendees can view the presentation on the conference site until December 3, and it will also be accessible via the company's Investors section starting November 30. Protagonist focuses on developing peptide-based therapeutics for unmet medical needs, with three clinical-stage assets targeting blood disorders and inflammatory bowel disease.
Protagonist Therapeutics (NASDAQ:PTGX) announced that its President and CEO, Dinesh V. Patel, will join a fireside chat at the Jefferies Virtual 2020 London Healthcare Conference. The event is scheduled for November 17, 2020, at 5:35 p.m. GMT (12:35 p.m. EST). A live and archived webcast will be accessible via the company's website and the provided links.
Protagonist is a clinical-stage biopharmaceutical company focusing on developing peptide-based therapeutics for significant medical needs, currently advancing three clinical-stage assets.
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