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Q32 Bio to Report 36-Week Topline Results from Part B of SIGNAL-AA Clinical Trial of Bempikibart in Alopecia Areata on July 13, 2026

(Moderate)
(Neutral)
Tags
earnings date clinical trial

Q32 Bio (Nasdaq: QTTB), a clinical-stage biotechnology company developing therapies for alopecia areata and other autoimmune and inflammatory diseases, will report 36-week topline results from Part B of the SIGNAL-AA Phase 2a trial of bempikibart in severe or very severe alopecia areata on Monday, July 13, 2026.

According to Q32 Bio, the company will host a live conference call and webcast with accompanying slides at 8:00 a.m. E.T. the same day to discuss the results. Investors can access the live or recorded webcast via the Investors section of the Q32 Bio website or join the live call by dialing 1-800-836-8184 in the United States or 1-646-357-8785 from other locations, or by logging into the provided webinar link.

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Market reaction after SIGNAL-AA Phase 2a topline date: QTTB +90.72% in the Jul 13 session

+90.72% 6.8x vol
70 alerts
+90.72% Session close to close
+42.5% Peak Tracked
-8.6% Trough Tracked
$238.75M Market Cap
6.8x Rel. Volume

In the Jul 13 session, QTTB gained 90.72%, reflecting a significant positive market reaction. Argus tracked a peak move of +42.5% during that session. Argus tracked a trough of -8.6% from its starting point during tracking. Our momentum scanner triggered 70 alerts that day, indicating high trading interest and price volatility. Trading volume was exceptionally heavy at 6.8x the daily average, suggesting very strong buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock surged +90.7% in the session following this news. A strong gain could reflect investors po...
Analysis

The stock surged +90.7% in the session following this news. A strong gain could reflect investors positioning ahead of the 36-week SIGNAL-AA Part B topline readout. Past financing and earnings news often aligned with upside, but the large $300,000,000 shelf leaves room for future dilution risk.

Key Figures

Topline results duration: 36-week Results date: July 13, 2026 Conference call time: 8:00 a.m. E.T. +2 more
5 metrics
Topline results duration 36-week Part B of SIGNAL-AA Phase 2a trial in severe or very severe AA
Results date July 13, 2026 Planned announcement of 36-week topline SIGNAL-AA Part B data
Conference call time 8:00 a.m. E.T. Scheduled call to discuss 36-week topline SIGNAL-AA Part B results
US dial-in 1-800-836-8184 Access number for live conference call
International dial-in 1-646-357-8785 Access number for live conference call outside United States

Historical Context

5 past events · Latest: May 27 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
May 27 Private placement financing Neutral +81.2% Announced approximately $55M private placement of stock and pre-funded warrants.
May 05 Earnings report Positive +2.0% Q1 2026 results and extended cash runway with additional financing proceeds.
Apr 08 Conference participation Neutral -7.3% Plan to participate in Needham healthcare conference fireside chat.
Mar 10 Earnings report Positive +17.4% Q4 2025 results, SIGNAL-AA updates, and cash runway into Q4 2027.
Feb 18 Conference participation Neutral -5.4% Announcement of appearance at Oppenheimer healthcare conference with webcast access.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent financing and earnings updates have often aligned with positive share moves, while conference-related news has sometimes seen negative reactions.

Key Terms

phase 2a, topline results, alopecia areata
3 terms
phase 2a medical
"SIGNAL-AA Phase 2a clinical trial evaluating bempikibart in patients"
Phase 2a is an early stage in testing a new medical treatment or drug, where the main goal is to assess its safety and find the right dosage. For investors, this stage indicates whether the treatment shows initial promise before moving on to larger, more definitive studies; progress here can influence expectations for future development and potential success.
topline results medical
"it will report 36-week topline results from Part B of the SIGNAL-AA"
Topline results are the initial, high-level summary of the most important outcomes from an event such as a clinical trial or a company reporting period — for a drug study this means whether the main goals were met and basic safety info, and for a company it often means headline revenue and profit figures. Investors care because these summaries act like a headline that quickly signals whether prospects have improved or worsened, often driving immediate market reactions before the full details are released.
alopecia areata medical
"developing innovative therapies for alopecia areata ("AA") and other"
Alopecia areata is an autoimmune condition in which the body's immune system mistakenly attacks hair follicles, causing round patches of hair loss on the scalp or body; severity ranges from small spots to widespread baldness. Investors watch it because successful treatments, clinical trial results, regulatory approvals, or shifts in prevalence can create or shrink markets for drugs and therapies, affecting the value of companies developing remedies—think of it as demand risk and regulatory risk for hair-loss products.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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-- Conference call to be held Monday, July 13th at 8:00 a.m. E.T. --

WALTHAM, Mass., July 10, 2026 /PRNewswire/ -- Q32 Bio Inc. (Nasdaq: QTTB) ("Q32 Bio"), a clinical stage biotechnology company focused on developing innovative therapies for alopecia areata ("AA") and other autoimmune and inflammatory diseases, today announced it will report 36-week topline results from Part B of the SIGNAL-AA Phase 2a clinical trial evaluating bempikibart in patients with severe or very severe AA on Monday, July 13, 2026. Following the announcement, Q32 Bio will host a conference call and webcast at 8:00 a.m. E.T. on Monday, July 13, 2026 to discuss the results.

Conference Call

Q32 Bio's live conference call and webcast with accompanying slides will begin on Monday, July 13, 2026 at 8:00 a.m. E.T. To access a live or recorded webcast of the call and accompanying slides, please visit the "Investors" section of the Q32 Bio website at www.Q32Bio.com. To access the live conference call, please dial 1-800-836-8184 from the United States or 1-646-357-8785 from other locations; to access the webcast please login to https://app.webinar.net/m5ZoPmkRXdL.

About Q32 Bio

Q32 Bio is a clinical stage biotechnology company whose science targets potent regulators of the adaptive immune system to re-balance immunity and is focused on developing innovative therapies for alopecia areata and other autoimmune and inflammatory diseases. About 700,000 people in the United States live with alopecia areata1, a disease which has a life-altering impact on patients and limited current treatment options. Q32 Bio is advancing bempikibart (ADX-914), a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function, for the treatment of alopecia areata in an ongoing Phase 2 program. The IL-7 and TSLP pathways have been genetically and biologically implicated in driving several T cell-mediated pathological processes in numerous autoimmune diseases.

For more information, visit www.Q32Bio.com.

1National Alopecia Areata Foundation

Availability of Other Information About Q32 Bio

Investors and others should note that Q32 Bio communicates with its investors and the public using its website www.Q32Bio.com, including, but not limited to, Q32 Bio's disclosures, investor presentations and FAQs, United States Securities and Exchange Commission (the "SEC") filings, press releases, public conference call transcripts and webcast transcripts, as well as on X (formerly Twitter) and LinkedIn. The information that Q32 Bio posts on its website or on X or LinkedIn could be deemed to be material information. As a result, Q32 Bio encourages investors, the media and others interested to review the information that it posts there on a regular basis. The contents of Q32 Bio's website or social media shall not be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, as amended. Certain information in this press release constitutes forward-looking statements and forward-looking information (collectively, ‎‎"forward-looking information") within the meaning of applicable securities laws. In some cases, but not necessarily in all cases, forward-looking information can be identified by the ‎use of forward-looking terminology such as "plans", "excited to", "targets", "expects" or "does not expect", "is expected", "an opportunity exists", ‎‎"is positioned", "estimates", "intends", "assumes", "anticipates" or "does not anticipate" or "believes", or variations of such words and ‎phrases or state that certain actions, events or results "may", "could", "would", "might", "will" or "will be taken", "occur" or "be ‎achieved". In addition, any statements that refer to expectations, projections or other characterizations of future events or ‎circumstances contain forward-looking information. Specifically, this press release contains forward-looking information relating to the expected timing for the announcement of and conference call discussing 36-week topline data from Part B of the SIGNAL-AA Phase 2a clinical trial of bempikibart in AA. Statements containing forward-looking information are not historical facts but instead represent management's current ‎expectations, estimates and projections regarding the future of our business, future plans, strategies, projections, anticipated events ‎and trends, the economy and other future conditions. Forward-looking information is necessarily based on a number of opinions, assumptions and estimates that, while considered reasonable by Q32 Bio as of the date of this press release, are subject to ‎known and unknown risks, uncertainties and assumptions and other factors that may cause the actual results, level of activity, ‎performance or achievements to be materially different from those expressed or implied by such forward-looking information. Such risks and uncertainties include, but not limited to, the risk that additional data, or the results of ongoing data analyses, may not support Q32 Bio's current beliefs and expectations for bempikibart, including with respect to the durability of clinical responses, the risk that ongoing and future clinical studies might be more costly than expected or might not yield anticipated results, that Q32 Bio may use its capital resources sooner than currently anticipated, that Q32 Bio may need additional funding to complete clinical studies, which may not be available on favorable terms or at all, and such other risks and uncertainties identified in the "Risk Factors" section of Q32 Bio's most recently Annual Report on Form 10-K for the year ended December 31, 2025, as filed with the Securities and Exchange Commission, and subsequent quarterly reports. Except as required by applicable securities laws, Q32 Bio undertakes no obligation to publicly update any forward-looking information, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.

Contacts:
Investors: Brendan Burns
Argot Partners
212.600.1902
Q32Bio@argotpartners.com  

Media: David Rosen
Argot Partners
646.461.6387
david.rosen@argotpartners.com

Q32 Bio Logo

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/q32-bio-to-report-36-week-topline-results-from-part-b-of-signal-aa-clinical-trial-of-bempikibart-in-alopecia-areata-on-july-13-2026-302822915.html

SOURCE Q32 Bio

FAQ

When will Q32 Bio (QTTB) report 36-week topline results from the SIGNAL-AA Part B trial?

Q32 Bio plans to report 36-week topline results from Part B of the SIGNAL-AA Phase 2a trial on Monday, July 13, 2026. According to Q32 Bio, the data will focus on bempikibart in severe or very severe alopecia areata.

What is the purpose of Q32 Bio’s July 13, 2026 conference call for QTTB investors?

The July 13, 2026 conference call will discuss 36-week topline results from Part B of the SIGNAL-AA Phase 2a trial. According to Q32 Bio, management will review data for bempikibart in patients with severe or very severe alopecia areata.

How can investors access Q32 Bio’s July 13, 2026 earnings-style webcast on the SIGNAL-AA trial results?

Investors can access the live or recorded webcast with slides through the Investors section of the Q32 Bio website. According to Q32 Bio, the webcast will start at 8:00 a.m. E.T. on July 13, 2026 and cover the topline trial results.

What are the dial-in numbers for Q32 Bio’s July 13, 2026 conference call about bempikibart?

For the live call, U.S. participants should dial 1-800-836-8184, while international participants should dial 1-646-357-8785. According to Q32 Bio, these numbers provide access to the conference discussing SIGNAL-AA Part B 36-week topline results.

What is being studied in Q32 Bio’s SIGNAL-AA Phase 2a trial of bempikibart?

The SIGNAL-AA Phase 2a trial is evaluating bempikibart in patients with severe or very severe alopecia areata. According to Q32 Bio, 36-week topline results from Part B of this study will be reported on July 13, 2026.

Where can I watch the Q32 Bio (QTTB) July 13, 2026 webcast on alopecia areata trial results?

You can watch the webcast via the Investors section on the Q32 Bio website or by logging into the provided webinar link. According to Q32 Bio, the webcast starts at 8:00 a.m. E.T. and will include accompanying slides.