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PAP Therapy Reduces Hospitalizations by 31% and ER Visits by 23% for People with Obstructive Sleep Apnea and Comorbid Insomnia

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ResMed presented 13 new clinical studies at SLEEP 2024, highlighting the effectiveness of PAP therapy for Obstructive Sleep Apnea (OSA) and comorbid insomnia (COMISA). Key findings include a 31% reduction in hospitalizations and a 23% decrease in ER visits among COMISA patients adhering to PAP therapy. The research also revealed a 17% prevalence of insomnia in adults across North America, Latin America, and the Caribbean, and higher rates of depression in women with OSA. The studies underscore the importance of sleep health and PAP therapy in improving patient outcomes.

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Positive

  • PAP therapy reduces hospitalizations by 31% for COMISA patients.
  • ER visits decrease by 23% with PAP therapy adherence.
  • 17% prevalence of insomnia among adults in North America, Latin America, and the Caribbean highlights the need for better sleep health initiatives.
  • Research emphasizes the effectiveness of PAP therapy for OSA.
  • Clinical studies presented at a major event, SLEEP 2024, enhancing ResMed's credibility.

Negative

  • 25.5% of women with OSA and depression show lower adherence to PAP therapy.
  • Individuals with OSA and depression have a higher burden of severe obesity, hypertension, type 2 diabetes, coronary artery disease, and heart failure.
  • Higher rates of depression in women with OSA may indicate a need for more targeted interventions.

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ResMed studies presented at SLEEP 2024 also revealed a 17% prevalence of insomnia among adults in North America, Latin America, and the Caribbean, and a higher rate of depression in women with OSA

SAN DIEGO, June 10, 2024 (GLOBE NEWSWIRE) -- In collaboration with leading medical researchers from around the world, ResMed (NYSE: RMD, ASX: RMD) presented 13 new clinical studies at SLEEP 2024, the annual joint meeting of the American Academy of Sleep Medicine and the Sleep Research Society. Held in Houston, the event brought together scientific and medical experts focused on sleep health. From exploration into the prevalence of insomnia in the Americas to the reduction in emergency room visits among COMISA patients on PAP therapy – the ResMed-supported research demonstrated the effectiveness and value of positive airway pressure (PAP) treatment for OSA.

“The real-world evidence used in our clinical research continues to demonstrate the effectiveness of PAP therapy for treating OSA,” said Carlos M. Nunez, MD, ResMed’s Chief Medical Officer. “The studies presented at SLEEP 2024 expand our understanding of patients with sleep disorders by examining critical areas such as the effect of demographic factors like gender on sleep health. The body of knowledge we have created and are continually expanding with research partners who are highly respected in their fields helps ResMed and the medical community achieve the goal of helping people live their healthiest lives.”

Prevalence of Insomnia among Adults in the Americas Signals the Need to Prioritize Sleep Health
A study presented by Adam Benjafield, PhD, vice president of clinical research at ResMed, examined the prevalence of insomnia across Northern America, Latin America, and the Caribbean. Reviewing studies and survey data across 55 countries, the researchers extrapolated that approximately 17% of all adults in this region have insomnia and concluded this demonstrates the importance of sleep health as a priority within public health initiatives.

Adherence to PAP Therapy Linked to Fewer Hospital Visits Among Patients with OSA and Comorbid Insomnia
Atul Malhotra, MD, Director of Research for Pulmonary, Critical Care and Sleep Medicine at the University of California, San Diego, presented results of a study looking at the clinical and economic impact of treating OSA with PAP therapy among patients with OSA and comorbid insomnia, a combination known as COMISA. Using administrative claims data, the researchers found that all-cause hospitalizations and emergency room visits for these patients were lower among those who consistently adhered to PAP therapy when compared to those who demonstrated lower PAP adherence (all-cause hospitalizations per person 0.09 vs 0.13, p<0.001; emergency room visits per person 0.46 vs 0.60, p<0.001). The study concluded that PAP therapy, when adhered to, can improve health outcomes among patients with COMISA.

Women With OSA More Likely to Suffer from Depression and Fall Off PAP Therapy
Aimed at understanding the relationship between OSA and depression, ResMed’s clinical researchers and Sanjay Patel, MD, Medical Director, UPMC Comprehensive Sleep Disorders Program, analyzed more than 345K adults with OSA who had begun PAP therapy from administrative claims data. Of the nearly 17% with depression, one-fourth (25.5%) were women. In both women and men, individuals with depression had a greater burden of comorbidities including severe obesity, hypertension, type 2 diabetes, coronary artery disease and heart failure. The study also found lower adherence to PAP therapy among OSA patients with depression, particularly among women.

About ResMed
At ResMed (NYSE: RMD, ASX: RMD) we pioneer innovative solutions that treat and keep people out of the hospital, empowering them to live healthier, higher-quality lives. Our digital health technologies and cloud-connected medical devices transform care for people with sleep apnea, COPD, and other chronic diseases. Our comprehensive out-of-hospital software platforms support the professionals and caregivers who help people stay healthy in the home or care setting of their choice. By enabling better care, we improve quality of life, reduce the impact of chronic disease, and lower costs for consumers and healthcare systems in more than 140 countries. To learn more, visit ResMed.com and follow @ResMed.

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Peter Duckler Mike Ott
pduckler@realchemistry.com investorrelations@resmed.com
   
Rowena Kelley  
news@resmed.com  

FAQ

How effective is PAP therapy for reducing hospitalizations in COMISA patients?

PAP therapy reduces hospitalizations by 31% for patients with Obstructive Sleep Apnea and comorbid insomnia.

What impact does PAP therapy have on emergency room visits for COMISA patients?

Adherence to PAP therapy reduces emergency room visits by 23% among COMISA patients.

What is the prevalence of insomnia among adults in North America, Latin America, and the Caribbean?

The prevalence of insomnia among adults in these regions is approximately 17%.

Are women with OSA more likely to suffer from depression?

Yes, women with OSA are more likely to suffer from depression and show lower adherence to PAP therapy.

What additional health burdens do individuals with OSA and depression face?

Individuals with OSA and depression face higher rates of severe obesity, hypertension, type 2 diabetes, coronary artery disease, and heart failure.