Rein Therapeutics to Present Late-Breaking Poster at the European Respiratory Society (ERS) 2026 Congress
Rein Therapeutics (RNTX) will present a late-breaking poster at the European Respiratory Society (ERS) 2026 Congress in Barcelona, Spain, on September 8, 2026.
Rhea-AI Summary
Rein Therapeutics (RNTX) will present a late-breaking poster at the European Respiratory Society (ERS) 2026 Congress in Barcelona, Spain, on September 8, 2026.
The poster, titled “Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study”, will be presented in the session “Immunological mechanisms in pulmonary fibrosis” (Poster PA6217) from 12:30–2:00pm CEST by Philip Molyneaux, MD. The company notes that the data have been published in Nature Communications.
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Key Figures
Historical Context
| Date | Event | Sentiment | 24h Move | Catalyst |
|---|---|---|---|---|
| Aug 20 | Fast Track designation | Positive | +0.2% | FDA granted Fast Track designation for LTI-03 in idiopathic pulmonary fibrosis |
| Aug 14 | 2Q26 earnings report | Positive | +2.4% | Reported second-quarter results and completed a public offering |
| Aug 04 | Clinical data publication | Positive | +2.4% | Published first-in-human LTI-03 data in Nature Communications |
| Jul 21 | Phase 2 enrollment | Positive | +6.0% | RENEW began enrolling across all five planned countries |
| Jun 11 | Trial expansion | Positive | +0.6% | First United Kingdom patient randomized in the RENEW trial |
24h Move is the share-price change in the day after each event; other market factors may also have contributed.
All five prior news events recorded positive 24-hour price reactions, although the magnitude varied by announcement.
Key Terms
idiopathic pulmonary fibrosis medical
dose escalation study medical
interstitial lung disease medical
AI-generated analysis. How Rhea-AI works. Not financial advice.
AUSTIN, Texas, Sept. 04, 2026 (GLOBE NEWSWIRE) -- Rein Therapeutics ("Rein") (NASDAQ: RNTX), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines in orphan pulmonary and fibrosis indications, today announced that it will present a late-breaking poster at the European Respiratory Society (ERS) 2026 Congress taking place September 5-9, 2026, in Barcelona, Spain.
Poster Presentation
Title: Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study
Poster Session: Immunological mechanisms in pulmonary fibrosis
Poster Number: PA6217
Date: Tuesday, September 8, 2026
Time: 12:30-2:00pm CEST
Presenter: Philip Molyneaux, MD, Professor of Interstitial lung disease at Imperial College London and the Asthma+Lung UK Chair of Respiratory Research and Consultant in Interstitial lung disease at the Royal Brompton Hospital
Data to be presented in the poster has been published in Nature Communications and can be viewed here.
About LTI-03
LTI-03 is a first-in-class, inhaled peptide therapy derived from Caveolin-1 biology, a key regulator of fibrotic signaling. The drug is designed to inhibit lung scarring while preserving alveolar progenitor cells that are critical for tissue repair and regeneration.
Early data suggests that LTI-03 may represent a dual-acting approach: slowing fibrosis and promoting lung healing.
About the RENEW Phase 2 Trial
Rein’s RENEW trial (ClinicalTrials.gov: NCT06968845) is a randomized, placebo-controlled Phase 2 clinical study designed to evaluate the safety, tolerability, and efficacy of LTI-03 in patients with idiopathic pulmonary fibrosis.
The study is expected to enroll approximately 120 patients across the United States, United Kingdom, Australia, Poland, and Germany. Patients will be randomized to receive one of two dose levels of LTI-03 or placebo. The primary endpoint is safety, measured by the incidence of treatment-emergent adverse events through Week 24, with change from baseline in forced vital capacity (FVC) as the primary efficacy endpoint.
About Rein Therapeutics
Rein Therapeutics is a clinical-stage biopharmaceutical company advancing a novel pipeline of first-in-class therapies to address significant unmet medical needs in orphan pulmonary and fibrosis indications. Rein’s lead product candidate, LTI-03, is a novel, synthetic peptide with a dual mechanism targeting alveolar epithelial cell survival as well as inhibition of profibrotic signaling. LTI-03 has received both Orphan Drug and Fast Track designations in the U.S.
Investor Contact
IR@ReinTx.com
