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Revolution Medicines, Inc. - RVMD STOCK NEWS

Welcome to our dedicated page for Revolution Medicines news (Ticker: RVMD), a resource for investors and traders seeking the latest updates and insights on Revolution Medicines stock.

Revolution Medicines, Inc. (RVMD) is a clinical-stage precision oncology company dedicated to discovering and developing innovative targeted therapies that address the unmet needs of cancer patients. The company leverages its proprietary product engine to target frontier oncology pathways, with a strong focus on the RAS and mTOR signaling pathways, which are crucial for cancer growth and survival. Revolution Medicines’ approach draws inspiration from nature and evolution, harnessing insights from natural products to guide the discovery and development of small molecules that modulate key cancer targets.

The company’s research and development pipeline features several promising candidates, including RMC-4630, a SHP2 inhibitor, and a portfolio of RAS(ON) inhibitors such as RMC-6236, RMC-6291, and RMC-9805. These novel therapies aim to inhibit the active form of RAS proteins, which are common drivers in numerous cancer types. Revolution Medicines is also advancing the SOS1 and 4EBP1/mTORC1 programs, which hold significant potential in combination treatment strategies.

Recent achievements highlight the company’s progress in clinical development. Notably, the RMC-6236 Phase 1/1b trial demonstrated promising clinical activity and a favorable safety profile in patients with advanced solid tumors harboring KRAS mutations. The trial results showed an objective response rate of 38% in non-small cell lung cancer (NSCLC) and 20% in pancreatic ductal adenocarcinoma (PDAC), with disease control rates of 85% and 87%, respectively.

In October 2023, Revolution Medicines announced a pivotal milestone with the merger with EQRx, Inc., enhancing its financial position and enabling further investment in its clinical programs. The merger is expected to add approximately $1.1 billion in net cash proceeds, supporting the advancement of their RAS(ON) and RAS Companion Inhibitors. Dr. Sandra Horning, a renowned oncologist and former Genentech executive, joined the board of directors, bringing invaluable experience to the company.

Revolution Medicines continues to engage the scientific community and stakeholders through presentations at major conferences and investor webcasts. The company remains committed to advancing its robust pipeline of oncology therapies, aiming to revolutionize the treatment landscape for RAS-addicted cancers and improve outcomes for cancer patients worldwide.

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Revolution Medicines (Nasdaq: RVMD) announced the publication of a study in Cancer Discovery demonstrating the efficacy of their RAS(ON) multi-selective inhibitor, RMC-7977, in preclinical models of KRAS-mutated non-small cell lung cancer (NSCLC). The inhibitor showed strong anti-tumor activity alone and in combination with the RAS(ON) G12C-selective inhibitor, RMC-4998. This combination resulted in significant tumor regression and prolonged time to tumor doubling, particularly in models resistant to current therapies. The study also identified long-term tumor cell persistence mechanisms, providing insights for future treatments. Revolution Medicines plans to conduct further trials with their investigational drug RMC-6236, aimed at treating various RAS-driven cancers.

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Revolution Medicines (Nasdaq: RVMD) will host an investor webcast to update on its RMC-6236 pancreatic ductal adenocarcinoma (PDAC) clinical development program. The webcast is scheduled for July 15, 2024, at 8:00 a.m. Eastern Time. Speakers include the company's management and Dr. Brian M. Wolpin from Harvard Medical School and Dana-Farber Cancer Institute. The event can be accessed via the company's 'Events & Presentations' page. A replay will be available for 14 days post-event.

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Revolution Medicines (Nasdaq: RVMD), a clinical-stage oncology company focusing on targeted therapies for RAS-addicted cancers, announced its participation in the Goldman Sachs 45th Annual Global Healthcare Conference. CEO Mark A. Goldsmith will present at a fireside chat on June 12, 2024, at 2:40 p.m. ET. The event will be held at the Loews Miami Beach Hotel in Miami, FL, with a live webcast accessible via the company's website. A replay will be available for 14 days post-conference.

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Revolution Medicines, Inc. (Nasdaq: RVMD) released its first quarter 2024 financial results and corporate progress update. The company is advancing its RAS-addicted cancer therapies, such as RMC-6236, into pivotal trials. Plans include expanding therapy reach, qualifying mutant-selective inhibitors, and exploring combination treatments. Despite revenue decline and increased expenses, the company aims to fund operations into 2027.

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Revolution Medicines, Inc. (Nasdaq: RVMD) will report its financial results for the first quarter of 2024 on May 8, 2024, after market close. The company is focused on developing targeted therapies for patients with RAS-addicted cancers. A webcast hosted by senior management will discuss the financial results and corporate progress.

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Revolution Medicines, Inc. announces the publication of a peer-reviewed research paper detailing the discovery and translation of RMC-6236, an investigational RAS(ON) multi-selective inhibitor, with promising preclinical data and case studies. The paper highlights the potential of RMC-6236 in inhibiting RAS-dependent tumor growth across multiple cancer types, achieving deep and durable tumor regressions. Case studies from the Phase 1/1b clinical trial show complete responses in patients with NSCLC and PDAC, supporting the anti-tumor activity of RMC-6236.
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Revolution Medicines, Inc. (RVMD) announces groundbreaking research on RMC-7977, a RAS(ON) multi-selective tri-complex inhibitor with potent anti-tumor activity in RAS-mutant pancreatic cancer. The two Nature papers highlight the discovery, translational implications, and broad-spectrum potential of RMC-7977 in targeting various RAS mutations.
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Revolution Medicines, Inc. (RVMD) CEO to speak at healthcare conferences. Mark A. Goldsmith, M.D., Ph.D., will be featured at the 23rd Annual Needham Healthcare Conference and the Stifel Targeted Oncology Forum. Webcasts available on the company's website.
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Revolution Medicines, Inc. (RVMD) will present multiple groundbreaking discoveries at the AACR Annual Meeting 2024, focusing on innovative therapies for RAS-addicted cancers. Key presentations include new RAS inhibitors, combination therapies, and potential biomarkers. The company aims to address drug resistance and enhance treatment outcomes for cancer patients.
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Revolution Medicines, Inc. (RVMD) announced financial results for Q4 and full year 2023, focusing on RAS(ON) inhibitors development. The company aims to advance RMC-6236 into pivotal trials for NSCLC and PDAC, expand its reach into earlier therapy lines and qualify mutant-selective inhibitors. With a year-end cash balance of $1.85 billion after acquiring EQRx, Revolution Medicines is well-positioned for future developments.
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FAQ

What does Revolution Medicines, Inc. specialize in?

Revolution Medicines specializes in developing novel targeted therapies for RAS-addicted cancers by focusing on frontier oncology targets within the RAS and mTOR signaling pathways.

What are some of the key products in Revolution Medicines’ pipeline?

Key products include RMC-4630 (SHP2 inhibitor), RMC-6236, RMC-6291 (KRASG12C), and RMC-9805 (KRASG12D), which are all RAS(ON) inhibitors currently in clinical development.

What recent achievements has Revolution Medicines reported?

Recent achievements include promising clinical trial results for RMC-6236 in advanced solid tumors with KRAS mutations and the completion of a merger with EQRx, Inc. to bolster financial resources.

What is the significance of the RMC-6236 Phase 1/1b trial?

The RMC-6236 trial demonstrated preliminary clinical activity and an acceptable safety profile in patients with NSCLC and PDAC, showing promising objective response and disease control rates.

How does the merger with EQRx benefit Revolution Medicines?

The merger with EQRx is expected to add approximately $1.1 billion in net cash proceeds, supporting the advancement of Revolution Medicines’ clinical pipeline and enhancing its financial position.

Who recently joined the board of Revolution Medicines?

Dr. Sandra Horning, a renowned oncologist and former executive at Genentech, joined the board of directors, bringing significant experience in oncology drug development.

What are RAS(ON) inhibitors?

RAS(ON) inhibitors are designed to inhibit the active form of RAS proteins, which are common drivers in various cancer types, thus potentially offering a new approach in cancer treatment.

How does Revolution Medicines generate insights for its drug discovery?

Revolution Medicines draws inspiration from nature and evolution, particularly focusing on natural products that can inform and guide the discovery of small molecules targeting cancer pathways.

What are some of the ongoing trials at Revolution Medicines?

Ongoing trials include the RMC-6236-001 Phase 1/1b trial for advanced solid tumors with KRAS mutations and the continued development of RAS(ON) inhibitors like RMC-6291 and RMC-9805.

How can investors stay updated on Revolution Medicines’ developments?

Investors can stay updated by attending investor webcasts, accessing the company’s website for news and presentations, and reviewing SEC filings and joint proxy statements.

Revolution Medicines, Inc.

Nasdaq:RVMD

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RVMD Stock Data

7.67B
164.99M
2.39%
98.79%
9.41%
Biological Product (except Diagnostic) Manufacturing
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