Welcome to our dedicated page for Sangamo Therapeutics news (Ticker: SGMO), a resource for investors and traders seeking the latest updates and insights on Sangamo Therapeutics stock.
Sangamo Therapeutics Inc (NASDAQ: SGMO) is a clinical-stage biopharmaceutical leader pioneering genomic medicines through innovative gene editing and gene therapy approaches. This dedicated news hub provides investors and researchers with timely updates on the company's scientific advancements, regulatory milestones, and therapeutic developments.
Access authoritative updates including press releases on clinical trial progress, partnership announcements with biotech leaders, and research breakthroughs in neurology, hemophilia, and rare genetic disorders. Our curated collection ensures you stay informed about SGMO's pipeline developments, including zinc finger protein therapies and in vivo genome editing applications.
Key content categories feature earnings reports, FDA regulatory updates, scientific publication highlights, and strategic collaboration news. Bookmark this page for direct access to primary source materials from Sangamo Therapeutics, maintaining your awareness of critical developments in precision genomic medicine.
Sangamo Therapeutics (Nasdaq: SGMO) has entered a global license agreement with Genentech to develop intravenous genomic medicines for neurodegenerative diseases. The deal focuses on Sangamo's zinc finger repressors targeting the tau gene, important in Alzheimer's and tauopathies, and another undisclosed neurology target. Sangamo is also licensing its proprietary AAV capsid, STAC-BBB, which has shown strong blood-brain barrier penetration.
Key financial terms include:
- $50 million in near-term upfront fees and milestone payments
- Up to $1.9 billion in potential development and commercial milestones
- Tiered royalties on net sales
Sangamo will handle technology transfer and preclinical activities, while Genentech will lead clinical development, regulatory interactions, manufacturing, and global commercialization.
Sangamo Therapeutics (Nasdaq: SGMO), a genomic medicine company, has scheduled its second quarter 2024 financial results release for Tuesday, August 6, 2024, after market close. The company will host a conference call at 4:30 p.m. Eastern on the same day to review the results and provide business updates.
Participants can register and access the call using a provided link, with a recommendation to join 10 minutes early. The call will offer options to dial in or use a dial-out feature for instant phone connection. A live webcast will be available on the Sangamo website's Investors and Media section, with a replay accessible afterwards under Events.
Sangamo Therapeutics (SGMO) reported on Pfizer's announcement of positive topline results from the Phase 3 AFFINE trial evaluating giroctocogene fitelparvovec, a gene therapy for hemophilia A. The trial met its primary objective of non-inferiority and superiority in total annualized bleeding rate (ABR) compared to routine Factor VIII replacement. Key findings include:
- Significant ABR reduction (1.24 vs 4.73)
- 84% of participants maintained FVIII activity >5% at 15 months
- 98.3% reduction in mean treated ABR
- Generally well-tolerated safety profile
Sangamo is eligible for up to $220 million in milestone payments and 14-20% royalties if approved. The therapy aims to provide long-term bleed protection with a single infusion.
In the PR, Sangamo Therapeutics reported recent business highlights, including raising $24 million in gross proceeds, progress in neurology pipeline, completion of dosing in Phase 1/2 STAAR study for Fabry disease, and ongoing discussions with potential Fabry collaboration partners. Pfizer anticipates BLA and MAA submissions for Hemophilia A collaboration in early 2025. Financially, Sangamo reported a net loss of $49.1 million in Q1 2024 compared to a net income of $21.1 million in Q1 2023, with revenues decreasing to $0.5 million from $158.0 million in the same period in 2023. The non-GAAP total operating expenses decreased to $43.6 million in Q1 2024 from $69.5 million in Q1 2023. Cash and cash equivalents were $54.4 million as of March 31, 2024.
Sangamo Therapeutics, Inc. presented pre-clinical data on their innovative Modular Integrase (MINT) technology, aimed at large-scale genome editing. The MINT platform utilizes Bxb1 to integrate large DNA sequences into the genome with potential applications in treating patients with unique mutations. The technology is designed to simplify manufacturing, reduce translocation risk, and enable targeted integration without the need for additional genome editing tools. The company views the MINT platform as a valuable tool for neurology-focused indications and potential collaborations in human disease and agricultural biotech.
Sangamo Therapeutics, Inc. (Nasdaq: SGMO) has announced the release of its first quarter 2024 financial results on Thursday, May 9, 2024. The company will hold a conference call at 4:30 p.m. Eastern on the same day to discuss financial results and provide business updates.
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