Welcome to our dedicated page for Skye Bioscience news (Ticker: SKYE), a resource for investors and traders seeking the latest updates and insights on Skye Bioscience stock.
Skye Bioscience, Inc. (Nasdaq: SKYE) generates news primarily through its clinical and corporate progress in metabolic health, with a focus on obesity and overweight. The company regularly issues press releases on its Phase 2a CBeyond™ trial of nimacimab, a peripherally restricted CB1-inhibiting monoclonal antibody, and on related clinical, preclinical, and corporate milestones.
Readers of the SKYE news page can expect updates on topline and extension data from the CBeyond Phase 2a study, including weight loss outcomes, body composition findings, and analyses of rebound weight gain after treatment discontinuation. Skye’s releases have highlighted the performance of nimacimab as a monotherapy and in combination with semaglutide, reporting clinically meaningful additional weight loss, changes in waist circumference, and observations about safety, gastrointestinal tolerability, and neuropsychiatric events.
The company also publishes news on preclinical diet-induced obesity models, where nimacimab has been evaluated alone and with incretin-based therapies such as tirzepatide. These announcements describe weight loss effects, post-treatment weight maintenance, and modulation of metabolic and inflammatory pathways in animal studies. In addition, Skye reports on Phase 1b data in metabolic-associated steatotic liver disease, conference presentations at scientific and medical meetings, and participation in healthcare and investor conferences.
Corporate and regulatory news items include financial results, business updates, and collaboration agreements, such as Skye’s non-exclusive global collaboration and license agreement with Halozyme Therapeutics to use ENHANZE drug delivery technology for higher-dose subcutaneous administration of nimacimab. For investors and observers tracking developments in obesity therapeutics and CB1 inhibition, the SKYE news feed offers a centralized view of Skye’s reported clinical data, preclinical research, partnering activity, and financial disclosures over time.
Skye Bioscience (SKYE) announced promising results from a preclinical study of its THCVHS prodrug combined with netarsudil. The combination achieved a maximum intraocular pressure (IOP) reduction of 32.4%, with a sustained reduction of 26.5% at nine hours, outperforming standard therapies like latanoprost. THCVHS alone demonstrated a 27.5% reduction in IOP, maintaining a 21.1% reduction over nine hours. This study reinforces THCVHS's potential as a leading glaucoma treatment and sets the stage for upcoming human trials, anticipated to commence later this year.
Skye Bioscience (SKYE) has initiated key steps in advancing its glaucoma treatment, THCVHS, into human clinical trials. The company has completed its Chemical, Manufacture and Controls (CMC) procedures necessary for GLP toxicology studies, which are crucial for FDA approval. Preclinical studies show THCVHS effectively lowers intraocular pressure, surpassing existing glaucoma treatments. Upcoming studies will assess THCVHS's neuroprotective properties and its combination efficacy with leading drugs. The Phase 1 human trial is expected to start by year-end, as regulatory approvals progress.
Skye Bioscience, Inc. (OTCQB: SKYE) announced that CEO Punit Dhillon will present a corporate overview at the upcoming Sequire Cannabis Investor Conference on April 20, 2021, at 12:30 PM EST, and at the Planet Microcap Showcase on April 22, 2021, at 10:30 AM EST. The company is focused on developing proprietary, synthetic cannabinoid-derived molecules to treat glaucoma and other unmet medical needs. Their lead molecule shows potential for lowering intraocular pressure in glaucoma patients, outperforming current treatments. For more details, visit www.skyebioscience.com.
Skye Bioscience (OTCQB: SKYE) announces CEO Punit Dhillon's participation in the Benzinga Biotech Small Cap Conference on March 25, 2021. He will engage in a virtual panel titled 'The Natural Solutions: Cannabis & Cannabinoids' at 11:40 AM EST and present a corporate overview named 'Unlocking the Pharmaceutical Potential of Cannabinoids' at 12:10 PM EST. The Company focuses on developing cannabinoid-derived molecules aimed at treating glaucoma and other serious diseases. Their lead candidate shows promise in lowering intraocular pressure, surpassing current treatments.
Skye Bioscience (OTCQB: SKYE) announced positive preclinical results for its THC prodrug, THCVHS, which showed no eye irritation in the EpiOcular TM MTT ET-50 assay. This non-irritating profile is vital for future clinical testing. Skye aims to develop cannabinoid-derived medicines with rigorous standards and will advance THCVHS into a Phase 1 study for glaucoma treatment anticipated in early 2022. The study's findings underscore the formulation's safety and support Skye's commitment to innovative therapeutic solutions for unmet medical needs.
Skye Bioscience (OTCQB: SKYE) announced the appointment of cannabinoid experts Giovanni Appendino, PhD, and Eduardo Muñoz, MD, PhD, to its scientific advisory board. CEO Punit Dhillon emphasized the significance of their expertise in advancing cannabinoid-based medicines. Dr. Appendino brings over 40 years of research experience, while Dr. Muñoz has significant expertise in cannabinoid pharmacology and inflammation. Their contributions aim to enhance Skye's pipeline, particularly its lead molecule targeting glaucoma, which has shown promise in preclinical studies.
Skye Bioscience, Inc. (OTCQB: SKYE) announced that CEO Punit Dhillon will present a corporate overview at the H.C. Wainwright Global Life Sciences Conference on March 09, 2021, at 7:00 AM EST. The company focuses on developing synthetic cannabinoid-derived molecules to treat glaucoma and other unmet medical needs. The presentation will be available on Skye's investor relations website. Skye's lead molecule shows potential in lowering intraocular pressure in glaucoma patients, offering a new therapeutic class.
Skye Bioscience, Inc. (OTCQB: SKYE) announced participation in three investment events in February 2021. CEO Punit Dhillon will present at the Small-Cap Growth Investor Conference on February 4 at 3:30 PM EST. He will also present at the Money Show February Virtual Expo on February 18 at 11:20 AM EST. VP Karam Takhar will present at the Benzinga Cannabis Capital Conference on February 25 at 10:40 AM EST. These presentations will provide insights into their innovative cannabinoid-derived therapies targeting glaucoma and other unmet medical needs.