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Silence Therapeutics Plc American Depository Share - $SLN STOCK NEWS

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Silence Therapeutics plc, Nasdaq: SLN, will participate in a fireside chat at the H.C. Wainwright 2nd Annual BioConnect Investor Conference. The Company focuses on precision engineered medicines to silence diseases, aiming to transform people's lives. The event will take place on May 20th, 2:30 p.m. ET, with a live webcast accessible on the Silence website and an archived replay available post-conference.

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Silence Therapeutics plc announced the retirement of Alistair Gray, an independent member of the Board of Directors since 2015, effective May 1, 2024. Alistair Gray made significant contributions during his tenure, marking a period of growth and transformation for the company under the leadership of Iain Ross and Craig Tooman. The Company transitioned into a global player focusing on RNA interference, developed a pipeline of innovative product candidates, and secured big pharma partnerships.

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Silence Therapeutics plc, Nasdaq: SLN, announced positive results from the APOLLO phase 1 study of zerlasiran in reducing Lp(a) levels, a genetic risk factor for cardiovascular disease. The findings, published in JAMA, show sustained reductions in Lp(a) concentrations with well-tolerated profiles, promising advancements in addressing cardiovascular disease.
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Silence Therapeutics plc, Nasdaq: SLN, reported positive topline 36-week data from an ongoing phase 2 study of zerlasiran in patients with high lipoprotein(a). The company also disclosed its financial results for the full year ended December 31, 2023, and highlighted recent business achievements.
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Silence Therapeutics plc (SLN) announced positive topline 36-week data from the ALPACAR-360 phase 2 study of zerlasiran for reducing Lp(a) levels in high-risk ASCVD patients. Zerlasiran demonstrated a highly significant reduction in Lp(a) levels, with a median percentage reduction of 90% or greater at week 36. Topline 48-week data is expected in 2Q 2024.
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Silence Therapeutics plc, Nasdaq: SLN, will release its financial and business results for Q4 and full year 2023 on March 13, 2024. The company will host a conference call to discuss the results and provide a business update.
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Silence Therapeutics (SLN) announces a $10 million milestone payment from AstraZeneca for the initiation of a phase 1 clinical trial under their siRNA collaboration. This marks the first clinical milestone under their partnership and the third program to enter the clinic from their mRNAi GOLD™ platform. The collaboration aims to develop innovative therapies for cardiovascular, renal, metabolic, and respiratory diseases, with potential milestone payments of up to $140 million in development and $250 million in commercialization, along with tiered royalties on net sales.
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Silence Therapeutics plc (SLN) announced an oversubscribed private placement of 5,714,286 of the Company’s American Depositary Shares at a purchase price of US $21.00 per ADS, representing a premium of approximately 11% to Silence’s 30-day volume-weighted average price. The aggregate gross proceeds of the Private Placement are expected to be approximately US $120.0 million before deducting placement agent fees and other offering expenses. Investors in the Private Placement include 5AM Ventures, Frazier Life Sciences, Logos Capital, Nextech Invest Ltd, Redmile Group, TCGX, and Vivo Capital.
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Silence Therapeutics plc, Nasdaq: SLN, will participate in a fireside chat at Guggenheim Healthcare Talks 6th Annual Biotechnology Conference on February 7th. The live webcast can be accessed via the Investors section of the Silence website. An archived replay of the webcast will be available following the conference.
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Silence Therapeutics plc (Nasdaq: SLN) promotes Curtis Rambaran, MD to Chief Medical Officer and Marie Wikström Lindholm, PhD to Chief Scientific Officer. Both have been instrumental to the company's clinical and scientific successes. Curtis' experience in leading successful early and late-stage development programs combined with his background in cardiovascular medicine will be invaluable to Silence's next phase of growth. Marie's extensive work in oligonucleotide therapeutics is impressive, and the company looks forward to her leading their efforts to innovate and further expand their footprint as a global siRNA leader.
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Silence Therapeutics Plc American Depository Share

Nasdaq:SLN

SLN Rankings

SLN Stock Data

1.05B
72.78M
16.99%
44.6%
0.35%
Pharmaceutical Preparation Manufacturing
Manufacturing
Link
United States of America
London

About SLN

silence therapeutics develops a new generation of medicines by harnessing the body’s natural mechanism of rna interference, or rnai, within its cells. our proprietary technology can selectively inhibit any gene in the genome, specifically silencing the production of disease-causing proteins. using our enabling delivery systems, we have achieved an additional level of specificity by delivering our therapeutic rna molecules exclusively to target cells. silence’s proprietary rna chemistries and delivery systems are designed to improve the stability of our molecules and enhance effective delivery to target cells, providing a powerful modular technology well suited to tackle life-threatening diseases. for more information, visit us at www.silence-therapeutics.com