Silence Therapeutics Plc Stock Price, News & Analysis

Silence Therapeutics plc (NASDAQ: SLN) announces management's participation in a virtual fireside chat at Guggenheim’s Genomic Medicines and Rare Disease Days on April 4th, 2023, at 2:10 p.m. ET. A live webcast will be accessible through the Investors section of Silence's website, with an archived replay available post-conference. Silence Therapeutics focuses on developing innovative medicines using RNA interference (RNAi) to target disease-related genes. Notable products include SLN360 for cardiovascular risk and SLN124 for hematological diseases. Collaborations with AstraZeneca and others enhance Silence’s research capabilities.

Virpax Pharmaceuticals, Inc. (NASDAQ: VRPX) has announced the appointment of Barbara A. Ruskin, Ph.D, J.D., to its Board of Directors, expanding the board to nine members. Dr. Ruskin, who has over 25 years of experience in life sciences and intellectual property law, previously served as Chief Intellectual Property and Innovation Officer at Silence Therapeutics (OTC: SLNCF). Her background includes advising pharmaceutical companies and managing patent portfolios for major biotech firms. The company is focused on developing non-addictive pain management products and is seeking FDA approval for its candidates.

Silence Therapeutics announces the appointment of Dr. Steven Romano as the new Chief Medical Officer and Head of Research and Development, succeeding Dr. Giles Campion, set to retire by year-end 2023. Dr. Romano, a non-executive director since July 2019, boasts over 25 years of pharmaceutical experience, including leadership roles at Mallinckrodt and Pfizer. The transition aims for a seamless leadership change while continuing Silence's growth in RNA interference therapies. Silence has also recently reacquired two siRNA assets from Mallinckrodt, indicative of ongoing strategic developments.

Silence Therapeutics plc announced its acquisition of exclusive worldwide rights to two siRNA drug targets previously under collaboration with Mallinckrodt Pharmaceuticals. No upfront payment is required, but future success-based milestones and low royalties on net sales are expected. This strategic move aims to enhance Silence's portfolio in complement-mediated diseases, showcasing confidence in the mRNAi GOLD™ platform. The ongoing collaboration with Mallinckrodt since July 2019 will retain rights to the SLN501 program. Silence continues to focus on developing treatments for significant unmet medical needs in cardiovascular and hematological areas.

Silence Therapeutics plc (Nasdaq: SLN) reports its financial results for Q4 and full year 2022, highlighting a net loss of £40.5 million, up from £39.4 million in 2021. Revenue increased to £17.5 million from £12.4 million, attributed to advancing collaborations. R&D expenses rose to £35.6 million, reflecting enhanced clinical studies. Notably, the company is progressing with its clinical pipeline, including the SLN360 program for cardiovascular diseases and SLN124 for hematological conditions, with topline data expected in Q4 2023. As of December 31, 2022, liquidity stood at £71.1 million, sufficient to fund operations into Q1 2024.

Silence Therapeutics plc (NASDAQ: SLN) will announce its fourth quarter and full year financial results for the period ending December 31, 2022, on March 15, 2023. The company specializes in developing precision medicines via its proprietary mRNAi GOLD™ platform, leveraging RNA interference technology to target specific genes related to diseases. A conference call is scheduled for 8:00 a.m. EDT / 12:00 p.m. GMT on the same day to discuss the results and provide a business update. The call will be accessible via webcast on the company's website.

The report titled "Polycythemia Vera Market Insights, Epidemiology, and Market Forecast -2032" offers a comprehensive analysis of the Polycythemia Vera market. In 2022, the U.S. Polycythemia Vera market size was approximately USD 1,500 million and is projected to grow through 2032. The report highlights that PharmaEssentia's Besremi is the only first-line therapy approved, while Incyte's Jakafi is the sole second-line treatment. Additionally, competition may arise from Protagonist Therapeutics' Rusfertide and Imago Biosciences' Bomedemstat, expected to launch in late 2024 and 2026 respectively. The report also discusses emerging therapies with potential market impact, including Silence Therapeutics' SLN124.

The Global Small Interfering RNA (SiRNA) Market is projected to reach $964.17 Million by 2030, with a CAGR of 8.6% from 2023 to 2030. Key insights show that liposome-based systemic therapy represents 52.01% of the market share. The cancer segment leads therapeutics with a 38.14% share, while research institutions account for 43.07% of applications. North America dominated the market in 2022 due to robust R&D activities. Significant partnerships, such as Silence Therapeutics with Hansoh Pharmaceutical, are accelerating market growth in the APAC region. The report emphasizes a focus on RNA functions and its therapeutic potential for various genetic disorders.

Silence Therapeutics plc, trading on Nasdaq under the symbol SLN, will have its President and CEO, Craig Tooman, present at the virtual SVB Securities Global Biopharma Conference on February 15 at 3:00 p.m. ET. The presentation will be accessible via the Investors section of the company’s website. Silence is focused on innovating precision medicines through RNA interference technology, targeting diseases with significant unmet needs. Key product candidates include SLN360 for cardiovascular risk and SLN124 for hematological diseases, complemented by collaborations with notable partners like AstraZeneca.