Welcome to our dedicated page for Protara Therapeutics news (Ticker: TARA), a resource for investors and traders seeking the latest updates and insights on Protara Therapeutics stock.
Protara Therapeutics, Inc. develops clinical-stage biotechnology programs for cancer and rare diseases. Company news centers on TARA-002, an investigational cell-based therapy being studied for non-muscle invasive bladder cancer and lymphatic malformations, including updates from the ADVANCED-2 trial in BCG-Unresponsive and BCG-Naïve NMIBC patient groups.
Recurring updates also cover IV Choline Chloride, an investigational phospholipid substrate replacement therapy for patients receiving long-term parenteral support. Other company announcements include clinical-conference presentations, FDA designation updates, financial results, equity compensation grants under Nasdaq rules, and capital-raising activity tied to Protara's development-stage pipeline.
Protara Therapeutics (Nasdaq: TARA) has announced an encore presentation of their THRIVE-1 study results at the ASPEN 2025 Nutrition Science & Practice Conference. The study revealed that 78% of patients dependent on parenteral support (PS) were choline deficient, with 63% of these patients showing liver dysfunction.
The company is developing intravenous (IV) Choline Chloride as a treatment for patients who cannot receive choline through oral or enteral nutrition. The treatment has received Fast Track designation from the FDA. Protara plans to initiate THRIVE-3, a registrational Phase 2b/3 trial, in the first half of 2025, which will include an 8-week dose confirmation phase with 24 patients, followed by a 24-week randomized, placebo-controlled phase with 100 patients.
Protara Therapeutics (NASDAQ: TARA) reported Q4 and full year 2024 results, highlighting significant pipeline progress. The company reported positive six-month data from the ADVANCED-2 trial of TARA-002 in NMIBC patients, showing a 72% complete response rate at six months and a favorable safety profile.
Financial highlights include $170.3 million in cash and equivalents as of December 31, 2024, including proceeds from a $100 million public offering, expected to fund operations into 2027. Q4 net loss was $12.8 million ($0.48 per share), with full-year 2024 net loss at $44.6 million ($2.17 per share).
Key upcoming milestones include: initial 12-month data from ADVANCED-2 trial by mid-2025, first patient dosing in THRIVE-3 registrational trial in 1H 2025, and an interim update from STARBORN-1 trial in pediatric LMs by end of 1H 2025.
Protara Therapeutics (Nasdaq: TARA), a clinical-stage company focused on developing therapies for cancer and rare diseases, has announced its upcoming participation in the TD Cowen 45th Annual Health Care Conference. The company's management will engage in a fireside chat scheduled for March 5, 2025, at 9:50 am ET in Boston.
Interested parties can access a live webcast of the presentation through the Events and Presentations section on Protara's investor relations website at https://ir.protaratx.com. The presentation recording will be available for a time after the event.
Protara Therapeutics (Nasdaq: TARA), a clinical-stage company focused on developing therapies for cancer and rare diseases, has announced its upcoming participation in the Oppenheimer 35th Annual Healthcare Life Sciences Conference. The company's management will engage in a virtual fireside chat scheduled for Wednesday, February 12, 2025, at 12:40 pm ET.
Interested parties can access a live webcast of the presentation through the Events and Presentations section on Protara's investor relations website at https://ir.protaratx.com. The presentation recording will be available for a time following the event.
Protara Therapeutics highlights recent updates and anticipated milestones for 2025. The company reported positive six-month data from the ADVANCED-2 trial of TARA-002 in NMIBC patients, showing a 72% complete response (CR) rate at six months and a favorable safety profile. Data from 12-month evaluable patients is expected mid-2025, with futility analysis results by the end of 2025.
Protara completed a $100 million public offering, extending its financial runway into 2027. The THRIVE-3 registrational trial of IV Choline Chloride in patients dependent on parenteral support is set to begin in the first half of 2025. Initial results from the Phase 2 STARBORN-1 trial of TARA-002 in pediatric LMs patients are expected by the end of the first half of 2025.
The company remains focused on developing therapies for cancer and rare diseases, with ongoing efforts in combination therapies and regulatory alignments for future trials.
Protara Therapeutics (Nasdaq: TARA), a clinical-stage company focused on developing transformative therapies for cancer and rare diseases, has announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference. The company's management will deliver a presentation on Thursday, January 16, 2025, at 7:30 am PT in San Francisco.
The presentation will be accessible through a live webcast on the Events and Presentations section of Protara's investor relations website at https://ir.protaratx.com. Interested parties who cannot attend in person can view the presentation online, and a recording will be available for a time afterward.
Protara Therapeutics (Nasdaq: TARA) has completed its public offering, raising $100 million in gross proceeds. The offering included 13,690,000 common stock shares at $6.25 per share and pre-funded warrants for 2,325,372 shares at $6.249 each. Underwriters received a 30-day option to purchase up to 2,402,305 additional shares. The company plans to use the proceeds to fund the clinical development of TARA-002 and other clinical programs, along with working capital and general corporate purposes. The offering was managed by TD Cowen, Cantor, LifeSci Capital, Oppenheimer & Co., and Scotiabank as joint book-running managers.
Protara Therapeutics (Nasdaq: TARA) has announced the pricing of its $100 million public offering, consisting of 13,690,000 common stock shares at $6.25 per share and 2,325,372 pre-funded warrants at $6.249 each. The company has granted underwriters a 30-day option to purchase up to 2,402,305 additional shares. The offering is expected to close on December 11, 2024.
The net proceeds will fund the clinical development of TARA-002 and other clinical programs, along with working capital and general corporate purposes. TD Cowen, Cantor, LifeSci Capital, Oppenheimer & Co., and Scotiabank are serving as joint book-running managers for the offering.
Protara Therapeutics (Nasdaq: TARA) has announced the commencement of an underwritten public offering of common stock shares and pre-funded warrants. The company plans to grant underwriters a 30-day option to purchase additional shares at the public offering price, less underwriting discounts and commissions. The net proceeds will be used to fund the clinical development of TARA-002 and other clinical programs, along with working capital and general corporate purposes. TD Cowen, Cantor, LifeSci Capital, Oppenheimer & Co., and Scotiabank are acting as joint book-running managers. The securities will be issued under a shelf registration statement that was declared effective on November 14, 2023.
Protara Therapeutics announced positive results from its ongoing Phase 2 ADVANCED-2 trial of TARA-002 in Non-Muscle Invasive Bladder Cancer (NMIBC) patients. The trial demonstrated a 72% six-month complete response rate across BCG exposures, with notable results in both BCG-Unresponsive (100%) and BCG-Naïve (64%) patients.
Key highlights include an 80% reinduction salvage rate and 100% of patients maintaining complete response from three to six months. The study showed a favorable safety profile with no Grade 2 or greater treatment-related adverse events. The dataset included 20 patients evaluable at three months, 18 at six months, and 3 at nine months, with data cutoff on November 19, 2024.