Welcome to our dedicated page for Terns Pharmaceuticals news (Ticker: TERN), a resource for investors and traders seeking the latest updates and insights on Terns Pharmaceuticals stock.
Terns Pharmaceuticals, Inc. (Nasdaq: TERN) is a clinical-stage oncology company whose news flow centers on the development of TERN-701, a highly selective, oral, allosteric BCR-ABL (BCR::ABL1) inhibitor for chronic myeloid leukemia (CML). Company updates describe TERN-701 as the lead program in a focused oncology pipeline, with detailed disclosures on clinical data, regulatory interactions and trial design.
News about Terns frequently highlights results from the CARDINAL trial (NCT06163430), a global multicenter Phase 1/2 study of TERN-701 in previously treated chronic phase CML. Press releases and related SEC filings summarize major molecular response (MMR) and deep molecular response (DMR) rates, safety and tolerability findings, and outcomes in heavily pretreated or difficult-to-treat patient subgroups, including those with prior exposure to other tyrosine kinase inhibitors.
Investors following TERN can also find announcements about regulatory milestones, such as U.S. FDA Fast Track designation for TERN-701 in CML, and information on anticipated clinical priorities and program milestones. Terns’ news includes details on scientific presentations at major conferences like the American Society of Hematology (ASH) Annual Meeting and other healthcare conferences where updated CARDINAL data and development plans are discussed.
In addition, Terns issues news on capital markets activity, including underwritten public offerings of common stock intended to support research, clinical trials, development and manufacturing of key product candidates. Corporate updates may also cover decisions regarding legacy metabolic programs, such as TERN-501, TERN-801 and TERN-601, and the company’s strategy to seek partners for these assets. This news page aggregates such disclosures, offering a centralized view of Terns Pharmaceuticals’ clinical progress, financial developments and strategic focus in oncology.
Terns Pharmaceuticals, a clinical-stage biopharmaceutical company (Nasdaq: TERN), is set to present at the H.C. Wainwright 24th Annual Global Investment Conference on September 14, 2022, at 2:00 p.m. ET. The company focuses on developing small-molecule therapies for serious diseases, including oncology, obesity, and non-alcoholic steatohepatitis (NASH). Interested investors can access a live audio webcast of the presentation on Terns' investor relations page, with a replay available for 30 days post-event.
Terns Pharmaceuticals has announced an underwritten public offering of 12,250,000 shares at $2.42 each and pre-funded warrants for 14,630,000 additional shares at $2.4199 each, targeting gross proceeds of approximately $65 million. The offering, which is set to close on August 16, 2022, is oversubscribed and led by new investors, including Fairmount and Venrock Healthcare Capital Partners. Proceeds will fund clinical studies in chronic myeloid leukemia, obesity, and ongoing trials for NASH, alongside general corporate purposes.
Terns Pharmaceuticals reported progress on its clinical trials for three drug candidates targeting chronic myeloid leukemia, obesity, and NASH. TERN-701 is advancing to a Phase 1 trial in China, while TERN-601 is on schedule to begin a Phase 1 obesity trial in 2023. The company initiated dosing for TERN-501 in a Phase 2a trial for NASH, with results expected in the second half of 2023. As of June 30, 2022, Terns has $140 million in cash, providing a financial runway into 2025, despite a net loss of $13.9 million for the quarter.
On July 27, 2022, Terns Pharmaceuticals (Nasdaq: TERN) appointed Dr. Radhika Tripuraneni to its Board of Directors. Dr. Tripuraneni, the Chief Development Officer at Prothena Corporation, boasts over 15 years of drug development experience. She aims to leverage her expertise to guide Terns in advancing its pipeline of small-molecule candidates targeting serious diseases such as NASH, obesity, and cancer. CEO Sen Sundaram emphasized her valuable support in generating meaningful clinical data for these significant unmet needs.
Terns Pharmaceuticals presented positive results from its Phase 1 trial of TERN-501 at the EASL International Liver Congress 2022. The treatment was well-tolerated and showed significant dose-dependent effects on key biomarkers after 14 days. The company also highlighted its pipeline, including TERN-101 and TERN-201, with promising data supporting their potential in treating non-alcoholic steatohepatitis (NASH). Terns announced they will initiate a combination NASH trial with TERN-501 and TERN-101, with results expected in late 2023.
On June 8, 2022, Terns Pharmaceuticals (Nasdaq: TERN) announced that five abstracts concerning its non-alcoholic steatohepatitis (NASH) programs have been accepted for presentation at The International Liver Congress 2022, scheduled for June 22-26 in London. Key presentations include results from a first-in-human trial of TERN-501 and safety data on TERN-101 and TERN-201, showcasing their potential efficacy and favorable safety profiles. All abstracts will be published in the Journal of Hepatology.
Terns Pharmaceuticals has appointed Kerry Russell, M.D., Ph.D., as its new chief medical officer, reporting to Erin Quirk, M.D., President and Head of Research & Development. This strategic move aims to enhance Terns' expertise, particularly in progressing its clinical pipeline targeting serious diseases like non-alcoholic steatohepatitis (NASH), obesity, and chronic myeloid leukemia. With several key clinical trial data readouts expected in the coming years, Terns is focused on advancing its promising pipeline candidates.
Terns Pharmaceuticals reported advancements in its clinical pipeline, including the opening of an IND for a Phase 2a trial of TERN-501 for NASH, expected to yield top-line data in late 2023. TERN-601 is in IND-enabling studies for obesity, with a Phase 1 trial initiation anticipated in 2023. Additionally, the Phase 1 trial for TERN-701, targeting chronic myeloid leukemia, has commenced in China. The company maintains a robust cash position of $151 million, projected to sustain operations into 2025, covering three expected clinical trial readouts.
Terns Pharmaceuticals, a clinical-stage biopharmaceutical company focusing on serious diseases like NASH and obesity, will present at the 21st Annual Needham Virtual Healthcare Conference.
The presentation is scheduled for April 11, 2022, at 2:15 p.m. ET. Investors can access a live audio webcast via Terns' investor relations webpage, with a replay available for 30 days post-event.
Terns is developing a diverse pipeline of therapies, including an FXR agonist and a VAP-1 inhibitor.
FOSTER CITY, Calif., March 21, 2022 – Terns Pharmaceuticals (Nasdaq: TERN) announced top-line results from Part 1 of the Phase 1b AVIATION Trial for TERN-201, a VAP-1 inhibitor aimed at treating non-alcoholic steatohepatitis (NASH). Part 1 met the primary safety endpoint, showing TERN-201 was well-tolerated with mild to moderate adverse events, but did not demonstrate significant changes in NASH biomarkers compared to placebo. Part 2 of the trial with a higher dose is ongoing, with results expected in H2 2022. Terns maintains a cash runway into 2024 and plans further trials for other candidates.