Welcome to our dedicated page for Tiziana Life Sciences Com news (Ticker: TLSA), a resource for investors and traders seeking the latest updates and insights on Tiziana Life Sciences Com stock.
Tiziana Life Sciences Ltd (TLSA) is a clinical-stage biotechnology innovator developing intranasal immunotherapies for neurodegenerative and inflammatory diseases. This page provides centralized access to official corporate announcements, clinical trial updates, and strategic developments.
Investors and researchers will find timely updates on TLSA's novel drug delivery platform, including progress with intranasal foralumab and other candidates targeting multiple sclerosis, Alzheimer's, and autoimmune conditions. The repository includes press releases on FDA communications, partnership announcements, and peer-reviewed research findings.
Key content categories include clinical trial milestones, intellectual property updates, executive leadership changes, and financial performance reports. All materials are sourced directly from the company and verified financial news outlets to ensure accuracy.
Bookmark this page for streamlined tracking of TLSA's progress in advancing non-invasive immunotherapy solutions. Check regularly for updates on groundbreaking approaches to modulating immune responses through nasal administration.
Tiziana Life Sciences (Nasdaq: TLSA) announced plans to investigate intranasal foralumab as a potential treatment for Long COVID, a condition affecting over 9 million Americans and costing the U.S. healthcare system approximately $2.6 trillion. The company emphasizes foralumab's role in deactivating activated microglia, critical in Long COVID's pathogenesis. Tiziana aims to enter a Phase 2a clinical trial pending FDA approval, using PET scans to assess the medication's effectiveness in reducing activated microglia after three months of use. The company believes that foralumab could represent a novel treatment for this debilitating condition, potentially benefiting a large patient population and addressing a significant unmet medical need.
Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced poster presentations on its lead asset, intranasal foralumab, at the "Preserving the Brain" scientific conference in Shanghai, running from March 31 to May 21, 2023. The event aims to foster discussions on neurodegenerative diseases among international experts. Gabriele Cerrone, Executive Chairman of Tiziana, expressed enthusiasm for foralumab's presentation, highlighting it as the only fully human anti-CD3 monoclonal antibody. Foralumab modulates T cell function which may aid in treating inflammatory conditions. Phase 2 trials for intranasal foralumab in patients with non-active SPMS are anticipated to begin in Q3 2023.
Tiziana Life Sciences (TLSA) announced promising findings related to the treatment of hemorrhagic stroke using intranasal anti-CD3 monoclonal antibodies. Dr. Saef Izzy's data indicates significant behavioral improvement in an animal model within one month post-treatment, supported by modulation of neuroinflammation through FoxP3+ Tregs. The research will be presented at the Annual American Academy of Neurology conference on April 23, 2023. The company aims to advance the clinical development of foralumab, the only fully human anti-CD3 monoclonal antibody, potentially transforming therapy for hemorrhagic stroke and improving neurological recovery outcomes.
Tiziana Life Sciences (TLSA) has announced plans to advance foralumab, a fully human anti-CD3 monoclonal antibody, into human trials targeting hemorrhagic stroke. Recent pre-clinical data indicates significant behavioral improvement in motor and cognitive functions one month after treatment in a model of intracerebral hemorrhage. The mechanism involves modulation of neuroinflammation through the induction of FoxP3+ Tregs, which may lead to enhanced recovery in stroke patients. Tiziana is actively pursuing clinical development, with Phase 2 trials of intranasal foralumab anticipated to initiate in Q3 2023.
Tiziana Life Sciences (NASDAQ: TLSA) announced promising results from a study on intranasal anti-CD3 monoclonal antibody for Alzheimer’s disease, to be presented at the AD/PD 2023 Conference on April 1, 2023. The study indicates reduced microglia activation and improved behavior in rodent models, suggesting that targeting neuroinflammation may enhance existing Alzheimer’s treatments. Dr. Howard Weiner highlighted that the research could complement FDA-approved therapies like aducanumab and lecanemab. Tiziana plans to initiate Phase 2 trials with foralumab in the third quarter of 2023, focusing on its immunomodulatory effects.
Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced that its Chairman and Acting CEO, Gabriele Cerrone, acquired 8,000 common shares at $0.89 each, raising his total holdings to 38,701,237 shares. The company specializes in breakthrough immunotherapies with innovative drug delivery methods. Its lead candidate, intranasal foralumab, is the only fully human anti-CD3 monoclonal antibody, showing potential in treating inflammatory diseases and demonstrating a favorable safety profile in initial studies. Phase 2 trials for foralumab are scheduled to begin in Q3 2023 for patients with non-active secondary progressive multiple sclerosis (SPMS).
Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced that Chairman and Acting CEO Gabriele Cerrone acquired 25,000 shares at $0.58 each, increasing his total ownership to 38,640,737 shares. The company focuses on developing immunomodulation therapies, particularly its lead candidate, intranasal foralumab, a fully human anti-CD3 monoclonal antibody. Phase 2 trials for foralumab are anticipated to commence in Q3 2023, targeting patients with non-active Secondary Progressive Multiple Sclerosis (SPMS). This innovative treatment route aims to enhance efficacy and tolerability compared to traditional IV delivery methods.
Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced its foralumab, the world’s only fully human anti-CD3 monoclonal antibody, highlighted in a FORBES article by William A. Haseltine. Foralumab, currently in clinical development, is designed to treat multiple sclerosis and other neurodegenerative diseases. The article emphasizes foralumab's ability to improve tissue remodeling and immune responses, suggesting it could enhance outcomes for COVID-19 patients as well. Phase 2 trials for non-active SPMS are expected to commence in Q3 2023, marking a significant advancement in the company's immunotherapy pipeline.
Tiziana Life Sciences Ltd. (Nasdaq: TLSA) announced a publication in the Proceedings of the National Academy of Sciences detailing the mechanism of action for intranasal foralumab, an immunomodulatory therapy. The study indicates that foralumab increases naïve-like T cells and Tregs while reducing effector T cells. This was observed across diverse patient groups including COVID and multiple sclerosis patients, as well as healthy volunteers. Tiziana plans to file an Investigational New Drug application for Alzheimer's research and initiate Phase 2 trials for non-active Secondary Progressive Multiple Sclerosis by Q3 2023.
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