Tiziana Life Sciences to Present at the 37th Annual Roth Conference

Rhea-AI Summary

Tiziana Life Sciences (Nasdaq: TLSA), a biotechnology company focused on developing breakthrough immunomodulation therapies, has announced its participation in the 37th Annual ROTH Conference from March 16-18, 2025, in Dana Point, California.

CEO Ivor Elrifi will lead a virtual fireside chat on Tuesday, March 18, 2025, at 12:00 pm PST (15:00 ET / 19:00 GMT). The company will also participate in one-on-one investor meetings during the conference.

The event will feature approximately 450 private and public companies from various growth sectors, offering opportunities for 1-on-1 meetings, analyst-selected fireside chats, and industry keynotes. Tiziana's lead development candidate is intranasal foralumab, a fully human, anti-CD3 monoclonal antibody.

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NEW YORK, March 17, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announced that the CEO of Tiziana Life Sciences, Ivor Elrifi, will be presenting during a fireside chat at the 37th Annual ROTH Conference and host 1x1 investor meetings. The Conference is being held March 16-18, 2025, in Dana Point, California. This year’s event will consist of 1-on-1 / small group meetings, analyst-selected fireside chats, industry keynotes and panels with executive management attending from approximately 450 private and public companies in a variety of growth sectors.

Presentation Details:
Date: Tuesday, March 18, 2025
Time of Presentation: 12:00 pm PST / 15:00 pm ET / 19:00 pm GMT
Format: Virtual Fireside Chat
1x1 Meetings: Please contact your ROTH representative.

You can register online to view the webcast here: Link

About Foralumab

Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 10 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (NCT06802328) with either an improvement or stability of disease seen within 6 months in all patients. The FDA has allowed an additional 20 patients to be enrolled in this EA program. In addition, intranasal foralumab is currently being studied in a Phase 2a, randomized, double-blind, placebo-controlled, multicenter, dose-ranging trial in patients with non-active secondary progressive multiple sclerosis (NCT06292923).

Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb) currently in clinical development, binds to the T cell receptor and dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets. This effect has been observed in patients with COVID and with multiple sclerosis, as well as in healthy normal subjects. The non-active SPMS intranasal foralumab Phase 2 trial (NCT06292923) began screening patients in November of 2023. Immunomodulation by nasal anti-CD3 mAb represents a novel avenue for treatment of neuroinflammatory and neurodegenerative human diseases.^[1],[2]

About Tiziana Life Sciences

Tiziana Life Sciences is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes of immunotherapy. Tiziana’s innovative nasal approach has the potential to provide an improvement in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana’s lead candidate, intranasal foralumab, which is the only fully human anti-CD3 mAb currently in clinical development, has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana’s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.

For more information about Tiziana Life Sciences and its innovative pipeline of therapies, please visit www.tizianalifesciences.com.

For further inquiries:

Tiziana Life Sciences Ltd
Paul Spencer, Business Development, and Investor Relations
+44 (0) 207 495 2379
email: info@tizianalifesciences.com

[1] https://www.pnas.org/doi/10.1073/pnas.2220272120

[2] https://www.pnas.org/doi/10.1073/pnas.2309221120

FAQ

When is Tiziana Life Sciences (TLSA) presenting at the 2025 ROTH Conference?

Tiziana Life Sciences will present on Tuesday, March 18, 2025, at 12:00 pm PST (15:00 ET / 19:00 GMT) through a virtual fireside chat.

What is Tiziana Life Sciences' (TLSA) main development product discussed at ROTH 2025?

Tiziana's lead development candidate is intranasal foralumab, a fully human, anti-CD3 monoclonal antibody for immunomodulation therapy.

How can investors meet with Tiziana Life Sciences (TLSA) at the ROTH Conference 2025?

Investors can arrange 1-on-1 meetings with Tiziana Life Sciences by contacting their ROTH representative.

What type of companies are participating in the 2025 ROTH Conference alongside TLSA?

Approximately 450 private and public companies from various growth sectors are participating in the conference.