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Entrada Therapeutics Appoints Maha Radhakrishnan, M.D., to its Board of Directors

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Entrada Therapeutics (NASDAQ: TRDA) has appointed Dr. Maha Radhakrishnan to its Board of Directors. Dr. Radhakrishnan currently serves as Executive Partner at Sofinnova Investments, bringing extensive experience in global drug development. She previously held the position of Group SVP and Chief Medical Officer at Biogen and served in leadership roles at Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group, and Cephalon. The appointment comes as Entrada advances its Duchenne muscular dystrophy franchise, with promising Phase 1 safety and target engagement data. The company aims to develop intracellular therapies for Duchenne and other serious diseases, with multiple patient-focused clinical trials planned throughout the year.
Entrada Therapeutics (NASDAQ: TRDA) ha nominato la Dott.ssa Maha Radhakrishnan nel suo Consiglio di Amministrazione. La Dott.ssa Radhakrishnan è attualmente Executive Partner presso Sofinnova Investments e vanta una vasta esperienza nello sviluppo globale di farmaci. In precedenza ha ricoperto il ruolo di Group SVP e Chief Medical Officer presso Biogen, oltre ad aver svolto posizioni di leadership in Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group e Cephalon. Questa nomina arriva mentre Entrada sta facendo progressi nella sua linea di ricerca sulla distrofia muscolare di Duchenne, con dati promettenti di sicurezza e coinvolgimento del target nella Fase 1. L’azienda punta a sviluppare terapie intracellulari per la distrofia di Duchenne e altre malattie gravi, con numerosi studi clinici focalizzati sui pazienti previsti nel corso dell’anno.
Entrada Therapeutics (NASDAQ: TRDA) ha nombrado a la Dra. Maha Radhakrishnan en su Junta Directiva. La Dra. Radhakrishnan actualmente es Socia Ejecutiva en Sofinnova Investments, aportando una amplia experiencia en el desarrollo global de medicamentos. Anteriormente, ocupó el cargo de Group SVP y Chief Medical Officer en Biogen y desempeñó roles de liderazgo en Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group y Cephalon. Este nombramiento se produce mientras Entrada avanza en su franquicia para la distrofia muscular de Duchenne, con datos prometedores de seguridad y compromiso del objetivo en la Fase 1. La compañía busca desarrollar terapias intracelulares para Duchenne y otras enfermedades graves, con múltiples ensayos clínicos centrados en el paciente planeados para todo el año.
Entrada Therapeutics(NASDAQ: TRDA)는 Dr. Maha Radhakrishnan을 이사회에 임명했습니다. Dr. Radhakrishnan은 현재 Sofinnova Investments의 Executive Partner로 재직 중이며, 글로벌 신약 개발 분야에서 풍부한 경험을 보유하고 있습니다. 그녀는 이전에 Biogen에서 Group SVP 겸 Chief Medical Officer를 역임했으며, Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group, Cephalon 등에서 리더십 역할을 수행했습니다. 이번 임명은 Entrada가 듀셴 근이영양증 분야에서 유망한 1상 안전성 및 타깃 관여 데이터를 바탕으로 사업을 진전시키는 가운데 이루어졌습니다. 회사는 듀셴 및 기타 중증 질환을 위한 세포 내 치료제를 개발하며, 올해 여러 환자 중심 임상시험을 계획하고 있습니다.
Entrada Therapeutics (NASDAQ : TRDA) a nommé la Dre Maha Radhakrishnan à son conseil d'administration. La Dre Radhakrishnan est actuellement Executive Partner chez Sofinnova Investments, apportant une vaste expérience dans le développement mondial de médicaments. Elle a précédemment occupé le poste de Group SVP et Chief Medical Officer chez Biogen et a exercé des fonctions de direction chez Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group et Cephalon. Cette nomination intervient alors qu’Entrada fait progresser sa franchise sur la dystrophie musculaire de Duchenne, avec des données prometteuses de sécurité et d’engagement de la cible en phase 1. La société vise à développer des thérapies intracellulaires pour la dystrophie de Duchenne et d’autres maladies graves, avec de multiples essais cliniques centrés sur les patients prévus tout au long de l’année.
Entrada Therapeutics (NASDAQ: TRDA) hat Dr. Maha Radhakrishnan in seinen Vorstand berufen. Dr. Radhakrishnan ist derzeit Executive Partner bei Sofinnova Investments und bringt umfassende Erfahrung in der globalen Arzneimittelentwicklung mit. Zuvor war sie Group SVP und Chief Medical Officer bei Biogen und hatte Führungspositionen bei Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group und Cephalon inne. Die Ernennung erfolgt, während Entrada seine Duchenne-Muskeldystrophie-Sparte vorantreibt und vielversprechende Phase-1-Daten zur Sicherheit und Zielbindung vorliegen. Das Unternehmen verfolgt die Entwicklung intrazellulärer Therapien für Duchenne und andere schwere Erkrankungen und plant im Laufe des Jahres mehrere patientenorientierte klinische Studien.
Positive
  • Appointment of experienced executive Dr. Radhakrishnan with extensive background in global drug development and commercialization
  • Promising Phase 1 safety and target engagement data for Duchenne muscular dystrophy program
  • Multiple patient-focused clinical trials planned throughout the year
  • Strategic addition to board during period of clinical advancement
Negative
  • None.

BOSTON, June 03, 2025 (GLOBE NEWSWIRE) -- Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced the appointment of Maha Radhakrishnan, M.D., to its Board of Directors.

“We are pleased to have Dr. Radhakrishnan join the Board at this time of tremendous clinical momentum at Entrada, led by the continued advancement of our Duchenne muscular dystrophy franchise. Dr. Radhakrishnan’s deep and meaningful experience in global drug development will be invaluable as we quickly advance our novel Duchenne programs into multiple patient-focused clinical trials throughout this year,” said Dipal Doshi, Chief Executive Officer at Entrada Therapeutics.

“I’m honored to join the Board of Entrada as it advances its clinical-stage portfolio of Duchenne therapies and its growing pipeline of novel approaches for devastating diseases,” said Dr. Radhakrishnan. “The promising Phase 1 safety and target engagement data, along with the urgent need for new treatments, reinforce the potential of Entrada’s approach to change the lives of people living with Duchenne. I look forward to working with Dipal and the Board to help bring this new class of intracellular therapies to patients and families affected by Duchenne and other serious illnesses.”

Since August 2024, Dr. Radhakrishnan has served as Executive Partner at Sofinnova Investments, a European venture capital firm focused on life sciences. At Sofinnova Investments, Dr. Radhakrishnan leads in-depth diligence across clinical-ready assets in multiple therapeutic areas and provides expertise to portfolio companies in areas including product development and commercialization. From January 2020 to March 2024, Dr. Radhakrishnan served as Group Senior Vice President and Chief Medical Officer at Biogen (NASDAQ: BIIB) where she was responsible for the worldwide medical function. Prior to Biogen, she served as Senior Vice President and Global Head of Medical, Primary Care Business Unit at Sanofi. Previously, she held several leadership roles at Bioverativ (acquired by Sanofi), Bristol Myers Squibb, UnitedHealth Group and Cephalon (acquired by Teva Pharmaceuticals). Dr. Radhakrishnan received her M.D. in Internal Medicine with honors from the People’s Friendship University in Moscow, Russia, as well as a Master's degree in the Russian language.

About Entrada Therapeutics
Entrada Therapeutics is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. The Company’s Endosomal Escape Vehicle (EEV™)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA- and protein-based programs for the potential treatment of neuromuscular and ocular diseases, among others. The Company’s lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

For more information about Entrada, please visit our website, www.entradatx.com, and follow us on LinkedIn.

Forward-Looking Statements
This press release contains express and implied forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release, including statements regarding Entrada’s strategy, future operations, prospects and plans, objectives of management, the validation and differentiation of Entrada’s approach and EEV platform and its ability to provide a potential treatment for patients, and expectations regarding global Phase 2 clinical studies for ENTR-601-44, ENTR-601-45 and ENTR-601-50, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “objective,” “ongoing,” “plan,” “predict,” “project,” “potential,” “should,” or “would,” or the negative of these terms, or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Entrada may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including the risks and uncertainties identified in Entrada’s filings with the Securities and Exchange Commission (SEC), including the Company’s most recent Form 10-K and in subsequent filings Entrada may make with the SEC. In addition, the forward-looking statements included in this press release represent Entrada’s views as of the date of this press release. Entrada anticipates that subsequent events and developments will cause its views to change. However, while Entrada may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Entrada’s views as of any date subsequent to the date of this press release.

Investor Contact
Karla MacDonald
Chief Corporate Affairs Officer
kmacdonald@entradatx.com

Media Contact
Megan Prock McGrath
CTD Comms, LLC
megan@ctdcomms.com

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/8e8494c3-7253-4862-8232-0adae43d1bfd


FAQ

Who is the new board member appointed to Entrada Therapeutics (TRDA)?

Dr. Maha Radhakrishnan, currently Executive Partner at Sofinnova Investments, was appointed to Entrada Therapeutics' Board of Directors

What is Dr. Radhakrishnan's experience in the pharmaceutical industry?

Dr. Radhakrishnan previously served as Group SVP and Chief Medical Officer at Biogen, and held leadership roles at Sanofi, Bioverativ, Bristol Myers Squibb, UnitedHealth Group, and Cephalon

What is Entrada Therapeutics' main focus in drug development?

Entrada Therapeutics is focused on developing intracellular therapies, particularly for Duchenne muscular dystrophy, with promising Phase 1 safety and target engagement data

What are Entrada Therapeutics' (TRDA) near-term clinical plans?

The company plans to advance multiple patient-focused clinical trials throughout the year, primarily focused on their Duchenne muscular dystrophy franchise

What is Dr. Radhakrishnan's current role before joining Entrada's board?

Dr. Radhakrishnan serves as Executive Partner at Sofinnova Investments, a European venture capital firm focused on life sciences, since August 2024
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