Rhelion Life Sciences' Wholly Owned Subsidiary Filament Health Signs Supply and Licensing Agreement with the Centre for Human Drug Research for PEX010 in a Study of Low and Medium Dose Psilocybin
Rhelion’s Filament unit will supply PEX010 for a CHDR low- and medium-dose psilocybin study in the Netherlands, pending approvals.
Rhea-AI Summary
Rhelion Life Sciences (TRUFF) announced a supply and licensing agreement for its psilocybin candidate PEX010 with CHDR in the Netherlands.
Through wholly owned subsidiary Filament Health, Rhelion will supply PEX010 capsules in 1 mg and 5 mg doses, plus matching placebo, and provide regulatory support for a CHDR-sponsored study of low and medium dose psilocybin under the EU Clinical Trials Regulation. The study, conducted with Leiden University’s PRSM Lab and supported by Norrsken Mind, remains subject to regulatory and ethics approval. PEX010 is a patented, GMP-manufactured botanical psilocybin available in standardized 1, 5 and 25 mg doses, with 0.5 mg planned, and is used in more than 80 research studies worldwide. Rhelion completed the acquisition of Filament, including 77 issued patents across 13 families, on April 30, 2026.
Positive
- Supply and licensing agreement for PEX010 with CHDR to support a low- and medium-dose psilocybin study in the Netherlands.
- Intellectual property base includes 77 issued patents across 13 patent families acquired with Filament Health.
- Research reach PEX010 supports more than 80 academic and philanthropic psilocybin research studies worldwide.
Negative
- None.
AI-generated analysis. How Rhea-AI works. Not financial advice.
- Filament will supply PEX010 1 mg and 5 mg capsules, with matching placebo, for a study of low and medium dose psilocybin sponsored by the Centre for Human Drug Research in Leiden, the Netherlands.
Toronto, Ontario--(Newsfile Corp. - September 17, 2026) - Rhelion Life Sciences Corp. (CSE: RHEL) (FSE: 4YX0) (OTCQB: TRUFF) ("Rhelion" or the "Company") an Ontario-based organization advancing innovation and research within the legal psychedelic sector. Through its wholly owned subsidiary Filament Health Corp. ("Filament"), the Company develops, manufactures and supplies PEX010, its patented, standardized, GMP manufactured botanical psilocybin drug candidate, to clinical research and compassionate access programs at leading institutions worldwide.
The Company is pleased to announce that Filament has entered into a supply and licensing agreement with the Centre for Human Drug Research ("CHDR") in Leiden, the Netherlands, for the supply of PEX010 for a CHDR study of psilocybin in the low and medium dose range. The study is being conducted by CHDR in collaboration with the PRSM Lab at Leiden University, and has received funding support from Norrsken Mind.
Under the agreement, Filament will supply PEX010 in 1 mg and 5 mg doses, together with matching placebo capsules, and will provide regulatory support for the clinical trial application under the European Union Clinical Trials Regulation. The study is subject to regulatory and ethics approval.
CHDR is the sponsor of the study. Filament is not the sponsor of the trial and is not responsible for its conduct.
PEX010, Filament Health's botanical psilocybin drug candidate, underscores Filament's position as a leading supplier of pharmaceutical grade natural psilocybin, supporting more than 80 academic and philanthropic research studies worldwide. PEX010 is available in a standardized dosing range of 1, 5 and 25 mg from a single drug candidate, with a 0.5 mg dose to follow, produced using Filament's proprietary and patented extraction, purification and stabilization methods, giving investigators consistent composition across every dose, every study and every research site. On April 30, 2026, the Company completed its previously announced acquisition of Filament Health Corp., including its lead drug candidate, PEX010, and its portfolio of 77 issued patents across 13 patent families.
About Rhelion Life Sciences:
Rhelion Life Sciences is a science and research led company advancing the natural psychedelic drug discovery and development sector. Through its wholly owned subsidiary Filament Health Corp., the Company is developing naturally derived psilocybin drug candidates, including its patented PEX010, and supporting clinical research and compassionate use programs with leading institutions around the world.
For additional information:
Todd Shapiro
Chief Executive Officer & Director
Tel: 647-204-7129
Email: todd@rhelion.com
Website: www.Rhelion.com
Cautionary Statement Regarding Forward-Looking Statements
This press release contains certain "forward-looking information" within the meaning of applicable Canadian securities legislation. Such forward-looking information and forward-looking statements are not representative of historical facts or information or current conditions but instead represent only the Company's beliefs regarding future events, plans or objectives, many of which, by their nature, are inherently uncertain and outside of the Company's control. Often, but not always, forward-looking statements and information can be identified by the use of words such as "plans", "expects" or "does not expect", "is expected", "estimates", "intends", "anticipates" or "does not anticipate", or "believes", or variations of such words and phrases or state that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved. Examples of such information include statements with respect to: the supply of PEX010 and placebo capsules to the CHDR study; the submission and approval of the clinical trial application under the European Union Clinical Trials Regulation; the initiation, conduct, enrolment and progress of the CHDR study; the therapeutic potential of psilocybin and PEX010, including at low and medium doses; demand for standardized natural psilocybin; the anticipated future availability of a 0.5 mg dose alongside the existing 1, 5 and 25 mg doses; the completed acquisition of Filament Health and the expected integration of Filament's clinical infrastructure and intellectual property; and the future development, commercialization and regulatory approval of PEX010.
Forward-looking information in this news release is based on certain assumptions and expected future events, namely: the continued ability of Filament and Psilo Scientific Ltd. to manufacture and supply PEX010; the performance by CHDR and Filament of their respective obligations under the supply and licensing agreement; the timely submission and approval of the clinical trial application; the continued progression and funding of the study; the ability to obtain and maintain any required regulatory permits and approvals, including clinical trial, ethics, import and export authorizations; the successful integration of Filament Health following the completed acquisition; and general business, market and economic conditions. Risks, uncertainties and other factors involved with forward-looking information could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information, namely: the risk that the clinical trial application is delayed or not approved; the risk that either party does not perform its obligations under the supply and licensing agreement; the risk that the supplied product does not meet specification on release testing; the risk that the study does not proceed, enrol or progress as anticipated, or does not produce positive or clinically meaningful results; the risk that funding for the study is reduced, delayed or withdrawn; delays in regulatory permitting, including clinical trial, ethics, import and export authorizations; regulatory or enforcement developments affecting the legal framework for psilocybin supply and research; the risk that the 0.5 mg dose does not become available as anticipated; the risk that integration of Filament Health is not completed as anticipated; and adverse changes in the regulatory or political landscape affecting psychedelic research and access, together with the other risk factors described in the Company's continuous disclosure documents available under the Company's profile on SEDAR+ at www.sedarplus.ca. Readers are cautioned that the foregoing list is not exhaustive.
Although the Company believes that the assumptions and factors used in preparing, and the expectations contained in, the forward-looking information and statements are reasonable, undue reliance should not be placed on such information and statements, and no assurance or guarantee can be given that such forward-looking information and statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such information and statements. The forward-looking information and forward-looking statements contained in this press release are made as of the date of this press release, and the Company does not undertake to update any forward-looking information and/or forward-looking statements that are contained or referenced herein, except in accordance with applicable securities laws.
Source: Rhelion Life Sciences Corp.
To view the source version of this press release, please visit https://www.newsfilecorp.com/release/314769
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
Who is sponsoring and conducting the psilocybin study using PEX010?
The Centre for Human Drug Research (CHDR) in Leiden is the sponsor of the low- and medium-dose psilocybin study, which is being conducted in collaboration with the PRSM Lab at Leiden University. Filament is not the sponsor of the trial and is not responsible for its conduct.
What PEX010 doses and dosage forms will be supplied for the CHDR study?
Filament will supply PEX010 in 1 mg and 5 mg capsule doses, together with matching placebo capsules, for use in the CHDR study of low and medium dose psilocybin.
What is the regulatory status of the CHDR psilocybin study with PEX010?
The study is subject to regulatory and ethics approval. Filament will provide regulatory support for the clinical trial application under the European Union Clinical Trials Regulation.
What is PEX010 and what standardized dose range is available?
PEX010 is Filament Health’s patented, standardized, GMP-manufactured botanical psilocybin drug candidate. It is available in a dosing range of 1, 5 and 25 mg from a single drug candidate, with a 0.5 mg dose planned to follow.
When did Rhelion complete its acquisition of Filament Health and its PEX010 program?
Rhelion completed its previously announced acquisition of Filament Health, including its lead drug candidate PEX010 and a portfolio of 77 issued patents across 13 patent families, on April 30, 2026.