Trevi Therapeutics, Inc. reports news on its clinical-stage biopharmaceutical development of Haduvio, an oral extended-release formulation of nalbuphine, for chronic cough in patients with idiopathic pulmonary fibrosis, non-IPF interstitial lung disease, and refractory chronic cough. Company updates commonly cover clinical trial results and plans, FDA interactions, medical-conference presentations, intellectual property, and the investigational status of Haduvio.
Trevi also reports financing and corporate updates tied to its development strategy, including common stock offerings, quarterly financial results, cash runway commentary, and participation in healthcare investor events.
Trevi Therapeutics, Inc. (NASDAQ: TRVI) announced its participation in two key conferences in August 2022. On August 16, CEO Jennifer Good will engage in a fireside chat at the Stifel Biotech Executive Summer Summit. On August 29, CMO Thomas Sciascia and Professor Toby Maher will co-host a workshop at the 6th Annual IPF Summit in Boston, emphasizing chronic cough treatment strategies. Trevi's investigational therapy Haduvio is being developed for prurigo nodularis and chronic cough in adults with idiopathic pulmonary fibrosis, with FDA Fast Track designation for itch treatment.
Trevi Therapeutics (Nasdaq: TRVI) will host a conference call and live audio webcast on August 11, 2022, at 4:30 p.m. ET, to discuss its Q2 2022 financial results and provide a corporate update. The company is developing Haduvio (oral nalbuphine ER) as a treatment for prurigo nodularis and chronic cough in patients with idiopathic pulmonary fibrosis. Haduvio has received FDA Fast Track designation for the treatment of itch. More information can be accessed on the company’s website.
Trevi Therapeutics (Nasdaq: TRVI), a clinical-stage biopharmaceutical company, will participate in The Twelfth London International Cough Symposium on July 13-14, 2022. The event will focus on advancements related to acute and chronic cough, including novel treatments. Trevi is developing Haduvio (oral nalbuphine ER) aimed at treating prurigo nodularis and chronic cough in idiopathic pulmonary fibrosis patients. Haduvio has received Fast Track designation from the FDA for reducing pruritus in affected adults, though its efficacy is yet to be evaluated by regulatory authorities.
Trevi Therapeutics (TRVI) announced positive results from its Phase 2b/3 PRISM trial evaluating Haduvio for treating prurigo nodularis. The trial achieved statistical significance with a 4-point reduction in the Worst Itch – Numerical Rating Scale (WI-NRS) for 25% of Haduvio patients compared to 14% for placebo (p=0.0157). Key secondary endpoints were also met. The drug's safety profile was consistent with prior studies. Topline results will be discussed in a conference call on June 29, 2022, at 8:30 am EDT, highlighting Haduvio's potential in addressing severe itching and enhancing quality of life.
Trevi Therapeutics, Inc. (Nasdaq: TRVI) announced that its President and CEO, Jennifer Good, will present at the 2022 BIO International Convention on June 13 at 4 PM PT in San Diego, CA. The convention is expected to attract over 15,000 leaders in biotechnology and pharma, focusing on networking and partnership opportunities. Trevi is developing Haduvio™, an investigational therapy for pruritus in prurigo nodularis and chronic cough in idiopathic pulmonary fibrosis, and is currently conducting Phase 2b/3 and Phase 2 clinical trials for these conditions.
Trevi Therapeutics, Inc. (Nasdaq: TRVI) announced significant advancements in its clinical development for Haduvio, targeting chronic cough in idiopathic pulmonary fibrosis (IPF) and chronic pruritus in prurigo nodularis (PN). The Phase 2 CANAL trial demonstrated a 77.3% reduction in cough frequency, leading to expedited development. The company completed a private placement raising $55 million to fund further clinical trials. As of March 31, 2022, Trevi reported $29.1 million in cash and cash equivalents and a net loss of $7.3 million for the quarter.
Trevi Therapeutics, Inc. (Nasdaq: TRVI) will host a conference call on May 12, 2022, at 4:30 p.m. EDT to discuss its Q1 2022 financial results and provide a corporate update. The call can be accessed via phone or through a live audio webcast on the company's website. Trevi is focused on developing Haduvio™, an investigational therapy aimed at treating pruritus in prurigo nodularis and chronic cough in idiopathic pulmonary fibrosis. Haduvio has received Fast Track designation from the FDA for its proposed indication.
Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company, will present at two significant events in May 2022. The LifeSci Partners Immunology & Inflammation Symposium is scheduled for May 11, featuring Jennifer Good (President and CEO) and Dr. Bill Forbes (CDO). Additionally, Trevi will participate in the H.C. Wainwright Global Investment Conference from May 23-26, with a virtual presentation on May 24. Trevi is developing Haduvio (nalbuphine ER) for treating chronic pruritus in prurigo nodularis and chronic cough in idiopathic pulmonary fibrosis.
Trevi Therapeutics, a clinical-stage biopharmaceutical company, will participate in a fireside chat at the 21st Annual Needham Virtual Healthcare Conference on April 12, 2022, from 10:15 a.m. to 10:55 a.m. EDT. CEO Jennifer Good and Dr. Bill Forbes will discuss the investigational therapy Haduvio for treating pruritus in prurigo nodularis and chronic cough in idiopathic pulmonary fibrosis. The event will be available via live webcast on the company’s website, with an archived replay accessible for 30 days.
Trevi recently reported significant results from its CANAL trial, showing a 77% reduction in daytime cough frequency.
Trevi Therapeutics (Nasdaq: TRVI) announced a private placement to raise approximately $55 million through the sale of 4,580,526 shares at $1.90 each and pre-funded warrants at $1.899. The funds will support the clinical development of Haduvio for chronic cough in idiopathic pulmonary fibrosis (IPF) and for working capital. The deal, led by Frazier Life Sciences and Venrock Healthcare Capital Partners, is expected to close around April 11, 2022, pending customary conditions. The shares are unregistered under the Securities Act and will be resold upon effective registration.