Trevi Therapeutics, Inc. reports news on its clinical-stage biopharmaceutical development of Haduvio, an oral extended-release formulation of nalbuphine, for chronic cough in patients with idiopathic pulmonary fibrosis, non-IPF interstitial lung disease, and refractory chronic cough. Company updates commonly cover clinical trial results and plans, FDA interactions, medical-conference presentations, intellectual property, and the investigational status of Haduvio.
Trevi also reports financing and corporate updates tied to its development strategy, including common stock offerings, quarterly financial results, cash runway commentary, and participation in healthcare investor events.
Trevi Therapeutics, Inc. (TRVI) reported its financial results for Q3 2021, highlighting a net loss of $7.3 million, a slight improvement from $7.4 million in Q3 2020. As of September 30, 2021, the company had cash and equivalents of $29.3 million. The Phase 2b/3 PRISM trial for Haduvio in chronic pruritus is 90% enrolled, with top-line data expected in 1H 2022. Additionally, Trevi raised $14.8 million post-quarter to support ongoing operations. The company emphasizes the large market potential for its investigational therapy targeting severe itch and chronic cough.
Trevi Therapeutics (Nasdaq: TRVI) announced that its senior leadership will participate in a virtual fireside chat and host investor meetings at the Stifel 2021 Virtual Healthcare Conference on November 15, 2021, with a presentation scheduled for 4 p.m. ET. The event will feature Jennifer Good (President and CEO), Lisa Delfini (CFO), and Bill Forbes (CDO). Investors can access a live webcast on Trevi's website, and an archived replay will be available for 30 days post-conference. Trevi is focused on developing Haduvio, an investigational therapy for serious neurologically mediated conditions.
Trevi Therapeutics (Nasdaq: TRVI) will host a conference call and live audio webcast on November 10 at 4:30 p.m. ET to discuss its Q3 2021 financial results and provide a corporate update. Trevi focuses on developing Haduvio™ (nalbuphine ER) for serious neurological conditions, conducting Phase 2b/3 trials for chronic pruritus and Phase 2 trials for chronic cough in idiopathic pulmonary fibrosis patients. Haduvio has received Fast Track designation by the FDA for prurigo nodularis, although its safety and efficacy are yet to be evaluated.
Trevi Therapeutics (Nasdaq: TRVI) announced that Dr. Bill Forbes, Chief Development Officer, will present at the 11th World Congress on Itch on October 22-23, 2021. The session will focus on the challenges in itch research and the drug development perspective. Trevi is developing Haduvio (nalbuphine ER) for serious neurologically mediated conditions, including chronic pruritus and chronic cough. Haduvio has received Fast Track designation from the FDA for prurigo nodularis. The company aims to address unmet medical needs in itch management.
Trevi Therapeutics (Nasdaq: TRVI) announced its participation in the Alliance Global Partners' Virtual Biotech & Specialty Pharma Conference on October 13, 2021. The company focuses on the development of Haduvio (nalbuphine ER) to treat serious neurologically mediated conditions. Currently, Trevi is conducting a Phase 2b/3 clinical trial for chronic pruritus related to prurigo nodularis and a Phase 2 trial for chronic cough in idiopathic pulmonary fibrosis patients. The investigational therapy has received Fast Track designation from the FDA for moderate to severe pruritus reduction.
Trevi Therapeutics (TRVI) announced a private placement with a healthcare-focused institutional investor, raising approximately $11.8 million. The agreement involves the sale of 2,373,201 shares of common stock and accompanying warrants, priced at $1.62 per share, as well as pre-funded warrants. The company plans to use the proceeds to advance its investigational therapy, Haduvio™, targeting neurologically mediated conditions such as chronic pruritus and chronic cough. The private placement is expected to close on October 4, 2021.
Trevi Therapeutics (Nasdaq: TRVI) reported Q2 2021 financial results, revealing a net loss of $9.8 million, a significant increase from a net loss of $7.4 million in Q2 2020. As of June 30, 2021, Trevi had $36.4 million in cash, down from $45.0 million at the end of 2020. Approximately 80% of participants have enrolled in the Phase 2b/3 PRISM trial for Haduvio, with top-line data expected in 1H 2022. The company is also progressing in its CANAL trial for chronic cough, and recently expanded its management team.
Trevi Therapeutics (Nasdaq: TRVI) has appointed Lisa Delfini as Chief Financial Officer and Danine Summers as Vice President of Medical Affairs. Delfini, with 30 years of experience, will oversee financial operations and capital activities. Summers, an accomplished Medical Affairs executive, will focus on educating healthcare professionals regarding Haduvio’s data and development. Both appointments are expected to strengthen Trevi's leadership as it advances its Phase 2b/3 PRISM trial and Phase 2 CANAL trial for Haduvio, aimed at treating serious neurologically mediated conditions.
Trevi Therapeutics, Inc. (Nasdaq: TRVI) will host a conference call and audio webcast on August 12, 2021, at 4:30 p.m. ET to discuss its financial results for the quarter ending June 30, 2021 and provide a corporate update. The company is focused on developing Haduvio (nalbuphine ER) for serious neurologically mediated conditions, currently conducting Phase 2b/3 clinical trials for chronic pruritus associated with prurigo nodularis and Phase 2 trials for chronic cough in idiopathic pulmonary fibrosis patients.
Trevi Therapeutics, Inc. (Nasdaq: TRVI) announced that CEO Jennifer Good will present at the 2021 BIO Digital conference on June 10-11 and June 14-18. Haduvio™ (nalbuphine ER), Trevi's investigational therapy for serious neurologically mediated conditions, is currently undergoing Phase 2b/3 trials for chronic pruritus and Phase 2 trials for chronic cough. The presentation is available to registered attendees from 9am ET June 10 until the conference ends on June 18, with an archived replay accessible for 30 days via Trevi's website.