10x Genomics Launches Xenium Catalyst Network
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The announcement of 10x Genomics' expansion of its Xenium Catalyst Network signifies a strategic move to enhance the accessibility and utility of its single cell and spatial biology technologies. This development is poised to facilitate research institutions' ability to obtain critical proof-of-concept data, which is integral for securing grants and making informed purchasing decisions.
Single cell and spatial biology are pivotal in advancing precision medicine, as they allow for the detailed analysis of individual cells within their spatial context, offering insights into complex biological processes and disease mechanisms. The involvement of reputable research institutions in the network underscores the credibility and potential of the Xenium platform to contribute to significant scientific advancements.
From an industry perspective, this collaboration is likely to drive increased adoption of 10x Genomics' technologies, potentially leading to growth in revenue streams and strengthening the company's market position. The strategic expansion of the network could also foster innovation in drug discovery and clinical diagnostics, particularly for intractable diseases like cancer.
The formation of the Xenium Catalyst Network represents a forward-looking investment by 10x Genomics into the expansion of its market reach and customer base. By collaborating with key research institutions, the company is enhancing its service offering, which may translate into a competitive advantage and increased sales penetration in the biotechnology sector.
The stock market often responds positively to such strategic initiatives, particularly when they involve novel technologies with broad applications in a high-growth industry. Investors may view this as a proactive approach to driving long-term value creation. It is important to monitor subsequent financial disclosures for evidence of the network's impact on the company's financial performance, including revenue growth and R&D efficiency.
However, investors should also consider the costs associated with expanding the network and the time required for these investments to bear fruit. The success of this initiative will likely hinge on the rate of technology adoption and the generation of tangible outcomes from the research facilitated by the network.
The integration of single cell spatial transcriptome analysis into the research workflow can be a game-changer for genomics research. By enabling detailed examination of cellular heterogeneity and interactions within tissues, this technology could accelerate the discovery of novel biomarkers and therapeutic targets.
The Xenium platform's high sensitivity and specificity are critical for detecting rare transcripts and delineating cellular subpopulations, which can be crucial in understanding disease pathology and progression. The involvement of established institutions like The McDonnell Genome Institute at Washington University School of Medicine adds a layer of validation to the platform's capabilities.
As the network grows, it will be important to assess the quality and reproducibility of the data generated across different sites. Consistency in data quality is essential for the platform's credibility and for driving broader adoption in the research community.
Founding Network Members Will Accelerate Access to Proof-of-Concept Data for Prospective Xenium Customers Worldwide
"Since we launched the Xenium Catalyst Program, the customer response has been off the charts," said Jim Wilbur, Chief Commercial Officer at 10x Genomics. "We're now thrilled to expand the program with four exceptional founding network members. These collaborators are as eager and committed as we are to providing a world-class experience and helping more researchers see firsthand the power and performance of Xenium on their own samples."
While many researchers can use the company's comprehensive menu of in situ datasets, the Xenium Catalyst Network will support researchers who require proof-of-concept data on specific samples to aid in grant applications, funding requests and purchasing decisions. Through the Catalyst Network, researchers can choose from a broad menu of custom and curated gene panels to directly experience Xenium's class-leading performance and high sensitivity and specificity on their own samples.
The Xenium Catalyst Network is intended to replicate and expand the best-in-class experience and data that researchers can expect when running Xenium in their own labs. The founding Catalyst Network Members are Macrogen Inc., K2bio, BioChain Institute Inc., and The McDonnell Genome Institute at Washington University School of Medicine. 10x Genomics expects to add more research institutions to the Xenium Catalyst Network in 2024.
K2bio
K2bio enables early-stage life science companies to develop the next generation of innovative therapies. K2 is at the forefront of single cell analysis, offering revolutionary solutions that enable researchers to explore cellular complexity with unprecedented precision.
"K2bio, a novel full service preclinical Contract Research Organization (CRO), welcomes our partnership with 10x Genomics and the Xenium Catalyst Network," said Kieron Jones, CEO at K2bio. "Leveraging our experience in translational services, we have chosen to be a part of the Xenium Catalyst Network because the platform provides quality data for rapid insight into the biology of complex tissues, which aids our unified goal to provide cutting edge technologies and services."
Macrogen, Inc.
Macrogen is a global leader in precision medicine with a mission to predict and diagnose diseases, and present personalized treatment through R&D based on genome big data and collaboration with medical institutes.
"Single cell spatial transcriptome analysis using Xenium is believed to be a new technology that adds spatial information to existing single cell analysis," said Changhoon Kim, CEO at Macrogen. "We are very honored to be a Catalyst Network member, as Macrogen has been objectively recognized for its competitiveness as a single cell leader. Macrogen plans to expand pharmaceutical services for new drug screening using in situ single cell analysis and in the future intends to provide global services for precise clinical diagnostic solutions for incurable diseases including cancer."
BioChain Institute Inc.
BioChain Institute Inc. has engaged in the field of biological sample analysis for more than 25 years, empowering top global pharma and academic leaders. Its goal is to advance accurate disease diagnosis and drug discovery by enabling its clients with a series of products and services, from sample collection and preparation to analysis, providing customers with complete solutions.
"We are excited to take this leap into expanding our partnership with 10x Genomics for providing single cell spatial services using the 10x Genomics Xenium In Situ platform," said Vidyodhaya (Vidya) Sundaram, VP of Business Development at BioChain Institute Inc. "With this collaboration, we aim to leverage 10x's extensive experience in translational research and product development to provide cutting edge technology globally."
The McDonnell Genome Institute at Washington University School of Medicine
The McDonnell Genome Institute is a world leader in the fast-paced, constantly changing field of genomics. The McDonnell Genome Institute has developed a highly efficient, scalable research pipeline to provide a variety of functional genomics options.
"Participating in the 10x Genomics Xenium Catalyst Network will help us deliver state-of-the-art spatial genomics services," stated Michael Heinz, Director of Research Operations at the McDonnell Genome Institute. "This collaboration provides our researchers with efficient pathways to acquire essential proof-of-concept data – an important step in securing grant funding or commercializing new technologies."
About 10x Genomics
10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or Twitter.
Forward Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will,""enable," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "estimate," "see," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s expectations regarding the continued growth, performance, utility and expansion of our Xenium platform and Xenium Catalyst Network. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management, and actual outcomes and results could differ materially from these statements due to a number of factors. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time.
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