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VolitionRx Files New Patent Protecting its Nu.Q® NETs Test for Ebola Triage and Treatment Monitoring

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Volition (NYSE AMERICAN: VNRX) filed a new patent application to protect use of its Nu.Q® NETs test for triaging and monitoring patients suspected of Ebola infection.

The CE-Marked automated assay and a finger-prick LFT prototype target frontline use in outbreak zones, with Volition actively seeking global strategic partners.

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Positive

  • Filed strategic patent application for Nu.Q® NETs Ebola triage and monitoring use
  • CE-Marked automated Nu.Q® NETs assay already used in multiple clinical programs
  • Finger-prick Nu.Q® NETs LFT prototype designed for bedside use in outbreak zones
  • Actively inviting global partners for field trials, scale-up, and deployment

Negative

  • None.

News Market Reaction – VNRX

-10.34%
12 alerts
-10.34% Session close to close
+17.0% Peak Tracked
-22.9% Trough Tracked
$19.33M Market Cap
1.2x Rel. Volume

In the Jun 3 session, VNRX declined 10.34%, reflecting a significant negative market reaction. Argus tracked a peak move of +17.0% during that session. Argus tracked a trough of -22.9% from its starting point during tracking. Our momentum scanner triggered 12 alerts that day, indicating notable trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock dropped -10.3% in the session following this news. A negative reaction despite patent expa...
Analysis

The stock dropped -10.3% in the session following this news. A negative reaction despite patent expansion would fit prior episodes where upbeat clinical or technical updates, such as sepsis LFT progress, coincided with selling. Shares around $2.32, far below the $6.57 200‑day MA and 87.66% under the 52‑week high, already reflected pressure. The market may have focused on broader sector weakness and existing resale registration for 17,968,090 shares, which can contribute to perceived overhang even alongside new IP announcements.

Key Figures

Ebola case fatality rate: around 50%
1 metrics
Ebola case fatality rate around 50% World Health Organization Ebola Disease Factsheet cited in article

Historical Context

5 past events · Latest: May 27 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
May 27 Commercial momentum update Positive +0.0% Reported Q1 2026 revenue growth and progress across multiple Nu.Q® programs.
May 14 Earnings and update Neutral -9.1% Detailed Q1 2026 financials, funding inflows, and development across Nu.Q® franchises.
May 11 Earnings call schedule Neutral -8.9% Announced timing and access details for the Q1 2026 earnings call.
May 6 Nu.Q Vet manuscript Positive +6.9% Submitted Nu.Q® Vet feline lymphoma manuscript tied to a potential $5M milestone.
Apr 29 Sepsis LFT progress Positive -5.0% Reported successful finger‑prick nucleosome detection in ICU sepsis patients via LFT prototype.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news usually sees price moves broadly aligned with sentiment, though some positive clinical/technical updates have met with selling pressure.

Recent Company History

Over the past months, VolitionRx has highlighted growing commercial traction, with Q1 2026 revenue around $1.0 million and a 300% year-over-year increase. Updates spanned multi‑billion‑dollar TAMs in cancer detection, Nu.Q® Vet, and sepsis/NETosis, plus feasibility data for finger‑prick nucleosome detection in ICU sepsis patients. A feline lymphoma Nu.Q® Vet manuscript, tied to a potential $5 million milestone, previously drew a positive reaction. Today’s Ebola‑focused Nu.Q® NETs patent continues the pattern of expanding clinical use cases on the same technology platform.

Key Terms

nucleosomes, neutrophil extracellular traps, septic shock, lateral flow detection, +4 more
8 terms
nucleosomes medical
"The Nu.Q® NETs test quantifies circulating nucleosomes and Neutrophil Extracellular Traps"
Nucleosomes are the basic units of DNA packaging in cells, where long strands of DNA are wrapped around small protein “spools” called histones, like thread wound on a bobbin. They matter to investors because how tightly DNA is wound affects which genes are turned on or off, making nucleosomes central to drug targets, diagnostics and epigenetic therapies that can alter gene activity and influence the value of biotech and pharma pipelines.
neutrophil extracellular traps medical
"quantifies circulating nucleosomes and Neutrophil Extracellular Traps (NETs) as early indicators"
Neutrophil extracellular traps (NETs) are web-like strands of DNA and proteins expelled by certain white blood cells to trap and neutralize invading germs, like a spider spinning a sticky web to catch insects. For investors, NETs matter because they are linked to inflammation, blood clots and chronic disease, making them potential targets for new diagnostics and therapies and a factor in safety and efficacy assessments for drug and device development.
septic shock medical
"early indicators of hyper-inflammation leading to septic shock and early mortality"
Septic shock is a life-threatening condition caused by a severe bodily response to infection that leads to dangerously low blood pressure and failing organs. Think of it like a city’s emergency systems collapsing after a major storm: hospitals need intensive care, special drugs and equipment, and longer stays. For investors, its incidence and treatment options matter because they affect demand for drugs, medical devices, hospital resources, trial outcomes, regulatory attention and potential liability costs.
lateral flow detection technical
"in addition to the recently announced capillary blood finger-prick lateral flow detection (LFT)"
A lateral flow detection is a rapid, low-cost diagnostic test that uses a paper strip to show the presence or absence of a target substance—like a virus, protein or hormone—by creating a visible line as fluid moves along the strip. Investors care because these tests are cheap to produce, deliver quick results without a lab, and can scale widely, affecting revenue, supply chains, regulatory approval paths and market demand for diagnostic companies.
filovirus medical
"bedside triage solution for severe filovirus outbreaks, creating a compelling pathway"
A filovirus is a family of closely related viruses that can cause severe, often life-threatening fever and bleeding disorders in humans and animals; well-known examples cause fast-moving outbreaks with high death rates. Investors watch filovirus news because outbreaks prompt urgent public-health responses, accelerate demand for diagnostics, treatments and vaccines, and can trigger travel, trade and regulatory changes that affect healthcare companies, insurers and broader market confidence—like a sudden storm forcing rapid shifts in many sectors.
disseminated intravascular coagulation medical
"The disease is characterized by a low white cell count, disseminated intravascular coagulation"
A severe medical condition in which the body’s clotting system goes haywire, forming many tiny clots inside blood vessels and then exhausting the proteins needed to stop bleeding, which can cause organ damage and uncontrolled bleeding. It matters to investors because it can dramatically affect patient outcomes, clinical trial results, regulatory approvals, liability exposure and healthcare costs—outcomes that can quickly change a company’s financial prospects.
immunosuppression medical
"disseminated intravascular coagulation, immunosuppression and septic shock."
Immunosuppression is the lowering of the immune system’s ability to fight infections and other threats, either from drugs, medical treatments, or underlying disease. For investors it matters because products or conditions that cause immunosuppression change a drug’s safety profile, patient eligibility, regulatory hurdles and market size—think of it like turning down a building’s alarm system, which can reduce false alarms but raises the risk of real break‑ins and affects downstream costs and demand.
triage medical
"offer an unprecedented bedside triage solution for severe filovirus outbreaks"
Triage is the process of sorting or prioritizing items based on their importance or urgency. In finance, it often involves evaluating investments, tasks, or issues to decide which ones need immediate attention and which can wait, helping individuals or organizations focus on what matters most. This approach ensures resources are used efficiently and critical matters are addressed promptly.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Seeks Strategic Partners to Deploy Nu.Q® Platform in Outbreak Zones

HENDERSON, Nev., June 3, 2026 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, today announces that it has expanded its robust intellectual property portfolio by filing a strategic patent application covering the use of its proprietary Nu.Q® technology in triaging and monitoring patients who are suspected of having contracted the Ebola virus.

Dr. Jake Micallef, Chief Scientific Officer, Volition commented:

"This filing yet again shows the breadth of utility of our technology:  it claims  the potential use of Volition's existing Nu.Q® NETs test for Ebola. The Nu.Q® NETs test quantifies circulating nucleosomes and Neutrophil Extracellular Traps (NETs) as early indicators of hyper-inflammation leading to septic shock and early mortality.  

"Our existing patented product portfolio includes the CE-Marked automated Nu.Q® NETs assay for use in centralized laboratories, in addition to the recently announced capillary blood finger-prick lateral flow detection (LFT). The LFT could offer an unprecedented bedside triage solution for severe filovirus outbreaks, creating a compelling pathway into underserved,  resource constrained countries, where laboratory infrastructure may be weak or non-existent.

"While existing Ebola diagnostics focus entirely on identifying the presence of the virus, Volition's technology focuses on the host's dysregulated immune response. The Nu.Q® NETs test measures H3.1 nucleosomes, which serve as an independent predictor of organ failure and mortality in patients with sepsis and COVID-19. Similarly, identification of elevated NETs levels prior to clinical deterioration may help field medics prevent disease spread and provide earlier, more effective treatment for Ebola-infected patients."

Meeting the Critical Need in Ebola

Ebola is a rare but severe illness in humans, with an average case fatality rate around 50%1 .  The disease is characterized by a low white cell count, disseminated intravascular coagulation, immunosuppression and septic shock.

The ongoing Ebola outbreaks across Sub-Saharan Africa highlight a persistent medical challenge: because initial symptoms are non-specific, clinicians in remote field facilities cannot easily identify infected patients sufficiently early to prevent disease spread and for early treatment. 

A Call for Strategic Partnerships

With its core laboratory automated assays already CE-Marked and in use in a number of clinical programs, Volition is looking to translate this technology into immediate field application. The company is actively inviting global health organizations, pharmaceutical developers, non-governmental organizations (NGOs), and distribution partners to collaborate on field trials, manufacturing scale-up, and potential deployment of its LFT prototypes in outbreak zones.

Mr. Remi Rabeuf, VP of Corporate Alliances and Strategic Partnerships, Volition said:

"Our Nu.Q® technology has demonstrated its potential to improve sepsis care in advanced Western settings and with this new patent filing and our successful finger-prick LFT prototype, we now hope to take this prognostic power into most low- and middle-income country healthcare settings.

"We are seeking the right institutional and commercial partners to help us get this low-cost, life-saving triage tool into the hands of frontline healthcare workers fighting Ebola."

For partnership, licensing, or media inquiries, contact our alliance team directly at mediarelations@volition.com.

  1. World Health Organization (Ebola Disease Factsheet).

About Volition

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early detection and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life.

Volition's research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London.

The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

Media Enquiries: Louise Batchelor, Volition, mediarelations@volition.com, +44 (0)7557 774620

Safe Harbor Statement

Statements in this press release or associated video or link may be "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as "expects," "anticipates," "intends," "plans," "aims," "targets," "believes," "seeks," "estimates," "optimizing," "potential," "goal," "suggests," "could," "would," "should," "may," "will" and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, Volition's expectations related to revenue opportunities and growth, the effectiveness and availability of Volition's blood-based diagnostic, prognostic and disease monitoring tests, Volition's ability to develop and successfully commercialize such test platforms for early detection of cancer and other diseases as well as serving as a diagnostic, prognostic or disease monitoring tools for such diseases, Volition's expectations regarding future publications, Volition's success in securing licensing and/or distribution agreements or other arrangements with third parties for its products, and Volition's expectations regarding the terms of such agreements or arrangements. Volition's actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition's failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition's development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition's failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition's intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition's business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

Nu.Q®, rNuq™, Nucleosomics™, Capture-PCR™ and Capture-Seq™ and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release or associated video or link are the property of their respective owners. Additionally, unless otherwise specified, all references to "$" refer to the legal currency of the United States of America.

Cision View original content:https://www.prnewswire.com/news-releases/volitionrx-files-new-patent-protecting-its-nuq-nets-test-for-ebola-triage-and-treatment-monitoring-302790033.html

SOURCE VolitionRx Limited

FAQ

What did Volition (VNRX) announce on June 3, 2026 about its Nu.Q® NETs Ebola test?

Volition announced filing a new patent application covering use of its Nu.Q® technology to triage and monitor patients suspected of Ebola infection. According to Volition, this extends its existing Nu.Q® NETs platform toward field use in severe filovirus outbreaks.

How could Volition's Nu.Q® NETs Ebola patent impact healthcare in outbreak zones?

The patent seeks to protect use of Nu.Q® NETs for early triage and treatment monitoring of suspected Ebola patients. According to Volition, the technology may help frontline medics identify hyper-inflammation and septic shock risk earlier, potentially supporting timelier intervention in low-resource settings.

What Nu.Q® NETs products does Volition (VNRX) mention for Ebola triage?

Volition highlights its CE-Marked automated Nu.Q® NETs assay for centralized laboratories and a capillary blood finger-prick lateral flow test prototype. According to Volition, the LFT could provide bedside triage in underserved, resource-constrained regions where laboratory infrastructure is weak or absent.

How does Volition's Nu.Q® NETs test work in relation to Ebola and sepsis?

The Nu.Q® NETs test quantifies circulating nucleosomes and Neutrophil Extracellular Traps as markers of hyper-inflammation. According to Volition, it measures H3.1 nucleosomes, described as an independent predictor of organ failure and mortality in sepsis and COVID-19, informing its Ebola triage concept.

What partnerships is Volition (VNRX) seeking for its Nu.Q® NETs Ebola program?

Volition is inviting global health organizations, pharmaceutical developers, NGOs, and distribution partners to collaborate on field trials, manufacturing scale-up, and LFT deployment. According to Volition, it aims to place a low-cost triage tool in the hands of frontline Ebola healthcare workers.

What clinical experience does Volition report for its Nu.Q® technology before this Ebola patent?

Volition notes that its core laboratory automated assays are CE-Marked and already in use in several clinical programs. According to Volition, Nu.Q® technology has demonstrated potential to improve sepsis care in advanced Western settings, underpinning its expansion toward Ebola applications.