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Volition Signs Co-Marketing and Services Agreement with Hologic

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VolitionRx (NYSE AMERICAN: VNRX) has signed a co-marketing agreement with Hologic Diagenode for its Nu.Q® Discover service, which provides epigenetic profiling solutions for drug development and research. The initial one-year agreement could potentially lead to Hologic becoming an exclusive provider of these services.

The Nu.Q® Discover program has an estimated total addressable market of $200 million annually. The partnership leverages Hologic's extensive experience and large client base, having recorded revenues exceeding $4 billion in 2024. The collaboration aims to expand Volition's presence in the pharmaco-epigenetics market by incorporating nucleosome-based biomarkers into Hologic's portfolio for various disease areas including oncology, cardiovascular, and neurodegenerative conditions.

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Positive

  • Partnership with Hologic, a company with $4 billion in 2024 revenue, expanding market reach
  • Access to Nu.Q® Discover's $200 million total addressable market
  • Potential for exclusive provider agreement with Hologic if successful
  • Strong validation of Volition's nucleosome-based biomarkers in clinical development

Negative

  • Initial agreement limited to one year
  • Exclusive provider status dependent on meeting undisclosed terms

News Market Reaction

+2.98% 3.3x vol
15 alerts
+2.98% News Effect
+15.1% Peak in 25 hr 49 min
+$2M Valuation Impact
$79M Market Cap
3.3x Rel. Volume

On the day this news was published, VNRX gained 2.98%, reflecting a moderate positive market reaction. Argus tracked a peak move of +15.1% during that session. Our momentum scanner triggered 15 alerts that day, indicating notable trading interest and price volatility. This price movement added approximately $2M to the company's valuation, bringing the market cap to $79M at that time. Trading volume was very high at 3.3x the daily average, suggesting strong buying interest.

Data tracked by StockTitan Argus on the day of publication.

HENDERSON, Nev., Sept. 29, 2025 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, today announces that it has signed an agreement with Hologic Diagenode ("Hologic") for the co-marketing of Volition's Nu.Q® Discover service.

The Nu.Q® Discover service provides drug developers and scientists with a range of state-of-the-art assays for rapid epigenetic profiling in disease model development, preclinical testing, and clinical studies from discovery to being market ready.

Under the agreement, Hologic (NASDAQ: HOLX) will co-market Nu.Q® Discover services of Volition with Hologic Customers for an initial one-year term. If successful, the aim is for Hologic to be appointed as an exclusive provider of those services, subject to further terms being agreed.

Dr. Jasmine Kway, Chief Executive Officer, Singapore Volition, said:

"This is a significant milestone for our Nu.Q® Discover program and will greatly expand customer access to our proprietary Nu.Q® Discover assays, which have an estimated total addressable market of $200 million annually".[1]

"Hologic has extensive experience, recording revenues of over $4 billion in 2024, from a large client base and international reach, providing tools to biotech and pharma companies and also  to academic and government organizations. We have seen strong growth in interest and revenue for our Nu.Q® Discover services and believe this partnership with Hologic will further accelerate the expansion of our Nu.Q® Discover services to a wider base of customers."

"The inclusion of our nucleosome-based biomarkers in Hologic's portfolio demonstrates a strong validation of their value in clinical development.

"We look forward to working with the Hologic team as we strengthen our position in the pharmaco-epigenetics market, to help us to grow our revenues."

Raphael Werding, Head of Life Sciences, Hologic, said:

"We are delighted to sign this agreement and add Nu.Q® Discover to our service offering. At Hologic, we have extensive experience not only in oncology but also in other disease areas such as cardiovascular, neurodegenerative, immunology and others; disease areas where we believe nucleosome quantification can provide additional valuable biological insights to our biotech, pharma and academic clients."

"By incorporating Nu.Q® Discover biomarkers into a client's study design we may identify specific epigenetic signatures associated with disease states and treatment responses and in turn help advance the field of personalized medicine."

"Our ultimate goal is to create value for our clients by helping match patients with the therapies most likely to benefit them, while sparing them from treatments unlikely to be effective."

"We are excited to immediately start marketing Nu.Q® Discover at conferences and webinars and look forward to a long term and fruitful collaboration with Volition."

About Nu.Q® Discover

Volition's Nu.Q® Discover program enables drug developers and scientists access to a range of state-of-the-art assays for rapid epigenetic profiling in disease model development, preclinical testing, and clinical studies from discovery to being market ready.

Nu.Q® Discover is built on proprietary nucleosome quantification technology. It is a valuable research tool for R&D professionals working within the field of pharmaco-epigenetics, studying the epigenetic basis for variation in response to drugs.

About Hologic, Inc.

Hologic, Inc. (NASDAQ: HOLX), is dedicated to developing innovative medical technologies that effectively detect, diagnose and treat health conditions and raise the standard of care around the world.  

One of its subsidiaries is Hologic Diagenode, a leading provider in the field of epigenomics, with over 20 years of expertise. Their services can help advance biomarker discovery and validation by combining the strengths of epigenomics and bioinformatics. This new dimension of epigenomics can offer novel insights that extend beyond genomics, aiding in early detection, patient screening, minimal residual disease (MRD) monitoring, and much more. They partner with clients to create a customized, end-to-end service utilizing the best available technology to shorten timelines for translational research and biomarker validation before clinical trials.

To learn more, visit www.hologic.com.

About Volition

Volition is a multi-national epigenetics company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help diagnose and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early diagnosis and monitoring have the potential not only to prolong the life of patients but also to improve their quality of life.

Volition's research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London. 

The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document.  Such website address is included in this document as an inactive textual reference only.

Media Enquiries:
Louise Batchelor, Volition, mediarelations@volition.com +44 (0)7557 774620

Investor Relations
Jeremy Feffer, LifeSci Advisors, jfeffer@lifesciadvisors.com, +1-212-915-2568

Safe Harbor Statement

Statements in this press release may be "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as "expects," "anticipates," "intends," "plans," "aims," "targets," "believes," "seeks," "estimates," "optimizing," "potential," "goal," "suggests," "could," "would," "should," "may," "will" and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, Volition's expectations related to revenue opportunities and growth, the timing, completion, success and delivery of data from clinical studies, the timing of publications, , the effectiveness and availability of Volition's blood-based diagnostic, prognostic and disease monitoring tests, Volition's ability to develop and successfully commercialize such test platforms for early detection of cancer and other diseases as well as serving as a diagnostic, prognostic or disease monitoring tools for such diseases, and Volition's success in securing licensing and/or distribution agreements with third parties for its products. Volition's actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition's failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition's development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition's failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition's intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition's business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this press release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

Nucleosomics, Capture-PCR and Nu.Q® and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release are the property of their respective owners.

1.Data on file, Volition Total Addressable Market Model

Cision View original content:https://www.prnewswire.com/news-releases/volition-signs-co-marketing-and-services-agreement-with-hologic-302569548.html

SOURCE VolitionRx Limited

FAQ

What is the new partnership between VolitionRx (VNRX) and Hologic?

VolitionRx has signed a co-marketing agreement with Hologic for its Nu.Q® Discover service, which provides epigenetic profiling solutions for drug development. The initial one-year agreement could lead to Hologic becoming an exclusive provider.

What is the market potential for VNRX's Nu.Q® Discover program?

The Nu.Q® Discover program has an estimated total addressable market of $200 million annually, with potential for expansion through Hologic's extensive client base.

How will the Hologic partnership benefit VolitionRx (VNRX)?

The partnership will expand customer access to Nu.Q® Discover assays through Hologic's large international client base, which includes biotech, pharma, academic, and government organizations. Hologic recorded revenues over $4 billion in 2024.

What disease areas will VNRX's Nu.Q® Discover target through the Hologic partnership?

The partnership will target multiple disease areas including oncology, cardiovascular, neurodegenerative, and immunology conditions, where nucleosome quantification can provide valuable biological insights.

When will Hologic begin marketing VNRX's Nu.Q® Discover service?

Hologic will immediately begin marketing Nu.Q® Discover at conferences and webinars, as stated in the announcement on September 29, 2025.
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