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Volition Sponsors Symposium at 15th Conference of the European Hidradenitis Suppurativa Foundation

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Volition (NYSE: VNRX) sponsored a symposium at the European Hidradenitis Suppurativa Foundation conference in Malta on Feb 5, 2026, presenting clinical data for the Nu.Q® NETs plasma assay in Hidradenitis Suppurativa (HS).

The company highlighted a recently released cohort study suggesting Nu.Q® NETs can classify HS severity and may guide treatment selection; a related poster was presented Feb 4. The assay is CE‑Marked and commercially available across 27 EU member states, three EEA countries, and the U.K., and Volition cited a $3.8 billion total addressable market.

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News Market Reaction – VNRX

-4.55%
2 alerts
-4.55% Session close to close
-5.8% Trough Tracked
$33.44M Market Cap
0.7x Rel. Volume

In the Feb 4 session, VNRX declined 4.55%, reflecting a moderate negative market reaction. Argus tracked a trough of -5.8% from its starting point during tracking. Our momentum scanner triggered 2 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights Volition’s effort to deepen clinical validation and awareness for Nu.Q®...
Analysis

This announcement highlights Volition’s effort to deepen clinical validation and awareness for Nu.Q® NETs in hidradenitis suppurativa, a condition affecting about 1% of the global population, and to position the assay within a cited $3.8 billion Total Addressable Market. It builds directly on the recently released HS cohort study and prior NETosis publications. Investors may track further clinical trials, adoption across the 27 EU and 3 EEA markets, reimbursement progress, and any follow-on capital-raising disclosed under the existing shelf registration.

Key Figures

HS prevalence: 1% of world population Conference date: February 5, 2026 Poster date: February 4 +5 more
8 metrics
HS prevalence 1% of world population Hidradenitis Suppurativa patient population cited in article
Conference date February 5, 2026 EHSF symposium presentation in Malta
Poster date February 4 NETs blood level poster at EHSF Conference
Total Addressable Market $3.8 billion Nu.Q® NETs indications TAM (Volition TAM Model)
EU member states 27 countries Nu.Q® NETs CE-Marked clinical availability
EEA countries 3 countries Iceland, Liechtenstein, Norway coverage
Conference edition 15th conference European Hidradenitis Suppurativa Foundation meeting
Department number 4th Department Internal Medicine department linked to presenting professor

Historical Context

5 past events · Latest: Jan 30 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jan 30 Reimbursement submission Positive +13.5% Preparing French reimbursement submission for Nu.Q® Cancer assays with HCL support.
Jan 27 Clinical data update Positive -0.2% Clinical study supports Nu.Q® NETs use in managing hidradenitis suppurativa.
Jan 20 Commercial expansion Positive +8.4% New vet lab partnerships extend Nu.Q® Vet Cancer test access in U.S. and Asia.
Jan 16 Conference symposium Positive +0.6% Sponsoring veterinary symposium to promote Nu.Q® Vet Cancer test usage in practice.
Jan 8 Financing deal Positive +24.2% $2.0M funding via senior secured convertible note and related warrant package.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent VNRX news has usually led to positive reactions, with only one mild divergence despite mostly constructive announcements.

Recent Company History

Over the last month, Volition has released a series of commercially focused and clinical-expansion updates. On Jan 8, it secured $2.0M funding via a convertible note and warrant package, followed by multiple veterinary and human-health Nu.Q® launches and access expansions through January. A Jan 27 release already highlighted Nu.Q® NETs in hidradenitis suppurativa, and the Jan 30 reimbursement submission news in France further underscored its push toward routine clinical use. Today’s HS-focused symposium fits this pattern of data dissemination and market-building around Nu.Q® NETs.

Key Terms

neutrophil extracellular traps (nets), netosis, biomarker, plasma biomarker, +4 more
8 terms
neutrophil extracellular traps (nets) medical
"Change of Neutrophil Extracellular Traps (NETs) Blood Levels to Surrogate..."
Neutrophil extracellular traps (NETs) are web-like strands of DNA and proteins expelled by white blood cells to trap and neutralize germs; imagine a sticky spider web that captures invaders. They matter to investors because excessive or persistent NET formation is linked to inflammation, organ damage, and disease progression, making NETs both potential biomarkers and drug targets—so therapies or tests that modify NETs can affect clinical outcomes and commercial value.
netosis medical
"The Nu.Q® NETs assay is CE-Marked to detect diseases associated with NETosis..."
Netosis is a process where a type of white blood cell ejects a sticky web-like mesh to trap germs, sacrificing itself in the process. While intended as a protective response, these nets can also spark inflammation, blood clots or tissue damage, so they matter to investors because drugs that alter netosis can become new therapies or safety risks, affect clinical trial outcomes, and influence regulatory and market value for companies working on related diagnostics or treatments.
biomarker medical
"circulating H3.1 nucleosomes as a biomarker for ongoing and future clinical..."
A biomarker is a measurable indicator found in the body, such as in blood or tissues, that provides information about health, disease, or how the body responds to treatment. For investors, biomarkers can signal the potential success or risk of medical products or therapies, influencing the value of related companies and industry trends. They act like signals or clues that help assess the progress of medical advancements and their market impact.
plasma biomarker medical
"Empowering Precision‑medicine approach through NETs Plasma Biomarker‑driven..."
A plasma biomarker is a measurable molecule or substance in blood plasma that indicates a biological condition, such as disease presence, progression, or response to treatment. Like a dashboard light in a car, it gives clinicians and researchers a quick, objective signal about what’s happening in the body. For investors, reliable plasma biomarkers can speed drug development, improve diagnostic tests, guide patient selection, and reduce regulatory and commercial risk, affecting a company’s valuation and market opportunity.
ce-marked regulatory
"The Nu.Q® NETs assay is CE-Marked to detect diseases associated with NETosis..."
CE-marked indicates a product meets European Union requirements for safety, performance and legal compliance, allowing it to be sold across the European Economic Area. For investors, a CE mark is like a passport or safety stamp — it reduces regulatory and market-entry risk, can speed sales and adoption across many countries, and signals the maker completed required testing and documentation, which can affect revenue forecasts and valuation.
total addressable market financial
"The market opportunity... is significant, with a Total Addressable Market of $3.8 billion..."
Total addressable market is the total potential sales opportunity for a product or service if it were to reach every possible customer. It helps investors understand the maximum size of the market and the growth potential for a business. Think of it as the entire pie available to be shared, indicating how big the opportunity could be.
nucleosomes medical
"potential use of circulating H3.1 nucleosomes as a biomarker..."
Nucleosomes are the basic units of DNA packaging in cells, where long strands of DNA are wrapped around small protein “spools” called histones, like thread wound on a bobbin. They matter to investors because how tightly DNA is wound affects which genes are turned on or off, making nucleosomes central to drug targets, diagnostics and epigenetic therapies that can alter gene activity and influence the value of biotech and pharma pipelines.
cohort study medical
"Plasma H3.1-Nucleosomes to Classify Severity... : A Cohort Study Bouazzi D..."
A cohort study follows a specific group of people who share a common trait (like exposure to a drug or treatment) over time to see how many develop a particular outcome, such as a health effect. For investors, cohort studies matter because they provide real-world evidence about a product’s safety, effectiveness or market need—think of tracking a cohort like watching a neighborhood over years to see who adopts a new service and whether it works as promised.

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 Showing New Indication for Nu.Q® NETs 

HENDERSON, Nev., Feb. 4, 2026 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, announces the sponsorship of a symposium at the European Hidradenitis Suppurativa Foundation (EHSF) Conference in Malta on 5th February. 

The session entitled "Empowering Precision‑medicine approach through NETs Plasma Biomarker‑driven personalized treatment"  will be presented by Professor Evangelos J. Giamarellos-Bourboulis, M.D., PhD, at the 4th Department of Internal Medicine, ATTIKON University General Hospital, Athens, Greece.

Professor Evangelos J. Giamarellos-Bourboulis commented:

"The scientific program at the EHSF conference this year provides a focus on genetics and updates on basic research, including the diagnosis and management of Hidradenitis Suppurativa (HS).

"I am delighted to present data from the recently released clinical study demonstrating the use of Volition's  Nu.Q® NETs assay in patient management for HS, a chronic lifelong disease, which affects approximately 1% of the world's population1.

"Since the advent of biologicals in the treatment of HS, there has been growing evidence that treatment response varies greatly so that some patients may experience substantial improvement, others no benefit at all and some may even worsen.

"Those considerations call for a precision medicine approach, which will be the focus of the Symposium. The findings from our study demonstrate that for the first time an easy-to-measure blood test, Nu.Q® NETs, can be used to classify HS patients and help guide treatment selection and modification.

"In addition, given the various biologic therapies currently in development, we will also explore the potential use of circulating H3.1 nucleosomes as a biomarker for ongoing and future clinical studies.

"Our hope is that trials can be started to study if Nu.Q® NETs can be used to guide both treatment initiation and early cessation of treatment."

Mr. Remi Rabeuf, VP Corporate Alliances and Strategic Partnership, Volition added:

"We are honored that leading expert Professor Giamarellos-Bourboulis is presenting the findings of his clinical study at the Volition sponsored symposium event at the EHSF Conference this week.

"This study, together with previously published evidence2-5 , demonstrates that Nu.Q® NETs should enable clinicians and researchers to anticipate disease, guide treatment decisions, and monitor patients over time, across both acute and chronic conditions.

"The Nu.Q® NETs assay is CE-Marked to detect diseases associated with NETosis and is therefore approved and commercially available for clinical use in 27 European Union (EU) member states, the three European Economic Area (EEA) countries (Iceland, Liechtenstein, and Norway) and the U.K.

"Nu.Q® NETs is a simple, low-cost, accessible test to detect diseases associated with NETosis. The market opportunity for such indications is significant, with a Total Addressable Market of $3.8 billion6."

A poster entitled "Change of Neutrophil Extracellular Traps (NETs) Blood Levels to Surrogate Response to Treatment in Hidradenitis Suppurativa" will also be presented at the Conference on Wednesday, February 4.

The recently released paper can be found in link below:

Plasma H3.1-Nucleosomes to Classify Severity and Surrogate Response to Treatment in Hidradenitis Suppurativa : A Cohort Study
 

  1. Bouazzi D, Nielsen SM, Hagan PG, et al. JAMA Dermatol. 2025. https://doi.org/10.1001/jamadermatol.2025.2373 
  2. Morimont et al. Biomolecules, 2022.  https://doi.org/10.3390/biom12081038
  3. Rahimi et al, Ann Intensive Care 2023. https://doi.org/10.1186/s13613-023-01204-y
  4. Daan F.L. Filippini et al.. Critical Care, 2025. https://doi.org/10.1186/s13054-025-05415-6
  5. Neumann et al, MedRXIV
  6. Data on File: Volition TAM Model.

About Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a lifelong, recurring condition that is often difficult to manage. The exact cause of HS is unknown however it is beyond any doubt a chronic neutrophilic disease.

HS is a painful skin condition that causes skin abscesses and scarring on the skin. It is thought to affect about 1 in 100 people.

It is important to recognise and diagnose the condition, including flare-ups, to prevent it getting worse. although the symptoms may improve or eventually stop with treatment.

The condition can have a significant impact on a person's everyday life. Having to regularly change dressings and constantly live with the pain and discomfort of the symptoms can affect a patient's  quality of life and lead to depression.

About Volition

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early detection and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life.

Volition's research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London.

The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

Media Enquiries: Louise Batchelor, Volition, mediarelations@volition.com, +44 (0)7557 774620

Safe Harbor Statement

Statements in this press release or associated video or link may be "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as "expects," "anticipates," "intends," "plans," "aims," "targets," "believes," "seeks," "estimates," "optimizing," "potential," "goal," "suggests," "could," "would," "should," "may," "will" and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, Volition's expectations related to revenue opportunities and growth, the effectiveness and availability of Volition's blood-based diagnostic, prognostic and disease monitoring tests, Volition's ability to develop and successfully commercialize such test platforms for early detection of cancer and other diseases as well as serving as a diagnostic, prognostic or disease monitoring tools for such diseases, Volition's expectations regarding future publications, Volition's success in securing licensing and/or distribution agreements with third parties for its products, and Volition's expectations regarding the terms of such agreements. Volition's actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition's failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition's development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition's failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition's intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition's business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

Nucleosomics, Capture-PCR, Capture-Seqand Nu.Q® and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release or associated video or link are the property of their respective owners. Additionally, unless otherwise specified, all references to "$" refer to the legal currency of the United States of America.

Cision View original content:https://www.prnewswire.com/news-releases/volition-sponsors-symposium-at-15th-conference-of-the-european-hidradenitis-suppurativa-foundation-302678836.html

SOURCE VolitionRx Limited

FAQ

What did Volition (VNRX) present about Nu.Q® NETs at the EHSF conference on Feb 5, 2026?

They presented clinical data showing Nu.Q® NETs can classify HS patients and inform treatment decisions. According to the company, the cohort study demonstrated blood levels of H3.1 nucleosomes correlate with disease severity and may act as a surrogate response marker for treatment.

What is the market opportunity Volition (VNRX) cites for Nu.Q® NETs?

Volition cites a total addressable market of $3.8 billion for NETosis-related indications. According to the company, that figure reflects the potential commercial opportunity for accessible NETs plasma biomarker testing across acute and chronic disease indications.

How might the Nu.Q® NETs assay impact treatment selection for Hidradenitis Suppurativa patients?

The assay may help classify patients and guide biologic therapy choices and modifications. According to the company, Nu.Q® NETs provides an easy-to-measure blood biomarker that could support precision-medicine decisions and monitoring of response over time.