Welcome to our dedicated page for Vor Biopharma news (Ticker: VOR), a resource for investors and traders seeking the latest updates and insights on Vor Biopharma stock.
Vor Biopharma Inc (VOR) is a clinical-stage biotechnology pioneer developing engineered hematopoietic stem cell (eHSC) therapies for hematological cancers. This page serves as the definitive source for verified corporate announcements, clinical trial updates, and strategic developments related to their innovative platform.
Investors and researchers will find timely updates on key milestones including trial progress, regulatory filings, and partnership announcements. All content is curated to provide actionable insights into the company’s novel approach to protecting healthy cells during cancer treatments while enabling targeted tumor eradication.
The resource features press releases covering financial results, manufacturing advancements, and peer-reviewed research publications. Scientific updates detail progress in their eHSC platform’s applications for CAR-T therapies and antigen-targeted treatment regimens.
Bookmark this page for streamlined access to Vor Biopharma’s latest developments in cell engineering and hematological oncology research. Regularly updated to reflect new data presentations, clinical collaborations, and pipeline expansions.
Vor Bio (Nasdaq: VOR) has appointed Sandy Mahatme as Chief Financial Officer and Chief Business Officer, effective July 9, 2025. Mahatme brings over 30 years of executive leadership experience in the biopharmaceutical industry, most recently serving as President, COO, and CFO of National Resilience, where he raised over $2.5 billion in capital.
At his previous role at Sarepta Therapeutics, Mahatme led capital formation efforts exceeding $3.5 billion and expanded the company's pipeline through strategic initiatives. The appointment comes as Vor Bio advances telitacicept through global Phase 3 development for generalized myasthenia gravis, with the drug already approved in China for multiple autoimmune indications.
Vor Bio (Nasdaq: VOR), a clinical-stage biotechnology company focused on autoimmune disease treatments, has granted its new Chief Executive Officer Jean-Paul Kress a significant stock option award. The inducement grant, approved on June 26, 2025, includes options to purchase 83,296,638 shares of common stock at an exercise price of $0.89 per share.
The stock option, granted under the Vor Biopharma Inc. 2023 Inducement Plan, has a ten-year term and follows a four-year vesting schedule. The vesting includes a 25% cliff after the first year, followed by monthly vesting over the subsequent 36 months, contingent on Dr. Kress's continued employment.
PureTech's (Nasdaq: PRTC) Founded Entity Vor Bio (Nasdaq: VOR) has secured an exclusive global license agreement with RemeGen for telitacicept, a novel dual-target fusion protein, along with a $175 million private placement. The license agreement grants Vor Bio rights outside Greater China and includes an initial payment of $125 million ($45M upfront + $80M in warrants), with potential regulatory and commercial milestones exceeding $4 billion plus tiered royalties.
Telitacicept, already approved in China for multiple autoimmune conditions, is currently in global Phase 3 trials with results expected in H1 2027. Additionally, Vor Bio appointed Dr. Jean-Paul Kress as CEO and Chairman, replacing Dr. Robert Ang.
The private placement involves issuing warrants for 700 million shares at $0.25 per warrant, closing expected on June 27, 2025.Vor Bio (Nasdaq: VOR) has secured a $175 million private placement through the issuance of prefunded warrants. The company will issue 700,000,000 warrants at $0.25 per warrant with an exercise price of $0.0001 per share.
The PIPE financing includes notable investors such as RA Capital Management, Mingxin Capital, Forbion, Venrock Healthcare Capital Partners, Caligan Partners, and NEXTBio. The proceeds will support the development of Vor Bio's clinical pipeline and general corporate purposes. The placement is expected to close on June 27, 2025, subject to stockholder approval and customary conditions.
Vor Bio (Nasdaq: VOR) has entered into an exclusive global license agreement with RemeGen for telitacicept, a novel dual-target fusion protein targeting autoimmune diseases. The deal grants Vor Bio rights outside Greater China for the late-stage asset, which is already approved in China for generalized myasthenia gravis (gMG), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA).
Under the agreement, RemeGen will receive an initial payment of $125 million ($45 million upfront plus $80 million in warrants), potential regulatory and commercial milestones exceeding $4 billion, and tiered royalties. A global Phase 3 trial is currently enrolling patients with results expected in H1 2027.
Additionally, Vor Bio appointed Jean-Paul Kress, MD, as CEO and Chairman, replacing Robert Ang. Dr. Kress brings significant experience from leadership roles at MorphoSys, Syntimmune, and other biopharma companies.
Vor Bio (VOR) has announced a strategic review process to maximize shareholder value amid challenging market conditions. The clinical-stage cell and genome engineering company is considering various options including asset sales, licensing, company sale, business combinations, or mergers. The company is immediately winding down its clinical and manufacturing operations, including ongoing clinical trials - a decision not related to safety concerns.
As part of this restructuring, Vor Bio has implemented a 95% workforce reduction costing approximately $10.9 million, retaining only 8 employees to manage the strategic process and maintain regulatory compliance. The company reported $91.9 million in cash and equivalents as of December 31, 2024, and has retained Cooley LLP as legal advisor. First quarter 2025 financial results will be reported on May 14, 2025.
PureTech Health reported strong results for 2024, highlighting significant clinical and financial achievements. The company's wholly-owned deupirfenidone showed positive Phase 2b results in IPF treatment, while LYT-200 demonstrated promising outcomes in cancer trials. A major milestone was the FDA approval of Cobenfy for schizophrenia.
The company maintained a robust financial position with $366.8 million in cash at PureTech level as of December 2024, providing operational runway into 2027. Notable achievements include their Founded Entity, Seaport Therapeutics, raising over $325 million.
Key developments include positive results from the ELEVATE IPF trial, with deupirfenidone showing potential to stabilize lung function. The company plans to initiate Phase 3 trials by end of 2025, subject to FDA feedback. PureTech's innovation engine has produced 29 therapeutic candidates, with three achieving FDA approval.
Vor Bio (VOR) has reported its Q4 and full-year 2024 financial results, highlighting progress in its cell and genome engineering platform. The company completed a $55.6 million private placement in December 2024, led by Reid Hoffman and RA Capital Management.
Key clinical updates include data from 25 patients treated with trem-cel, of which 15 received Mylotarg. The trial demonstrated durable engraftment and improved relapse-free survival. The VCAR33 clinical trial continues with strong enrollment, with data updates planned for H1 2025. The company plans to initiate the trem-cel+VCAR33 Treatment System clinical trial in H2 2025.
Financial highlights: Cash position of $91.9 million as of December 31, 2024, funding operations into Q1 2026. Q4 2024 R&D expenses were $25.3M (vs $20.9M in Q4 2023), while G&A expenses decreased to $6.0M (vs $7.2M in Q4 2023). Net loss for Q4 2024 was $30.7M compared to $26.3M in Q4 2023.
Vor Bio (VOR) presented research at the TANDEM Meetings highlighting challenges in cell and gene therapy (CGT) clinical trial enrollment. The study, involving 30 healthcare professionals and patient advocacy partners, identified key barriers including trial complexity, logistical challenges, and resource constraints at trial sites.
Key findings revealed that CGT trial enrollment requires more time compared to non-CGT trials due to complexity and patients' need for additional support. Despite these challenges, 100% of surveyed participants continue offering these trials to patients. Common patient concerns include fears about gene editing risks and caregiver requirements.
The research suggests opportunities for improvement through comprehensive educational content and specialized CGT research teams at institutions. The study included collaboration with notable institutions such as NMDP, MDS Foundation, Memorial Sloan Kettering Cancer Center, and Stanford Medicine.
Vor Bio (Nasdaq: VOR), a clinical-stage cell and genome engineering company, has announced its participation in Oppenheimer's 35th Annual Healthcare Life Sciences Conference. The company will engage in a fireside chat scheduled for Wednesday, February 12th at 12:00pm ET and conduct virtual one-on-one meetings with investors.
The event will be held virtually, and interested parties can access both the live webcast and archived replay of the fireside chat through the investors section of www.vorbio.com.
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