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The Vitamin Shoppe® Unveils First-of-its-Kind Supplement Line Formulated for GLP-1 Users

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The Vitamin Shoppe (VSI) has launched a pioneering supplement line called GLP-1 Support from Whole Health Rx, specifically designed for individuals using GLP-1 weight-loss medications. The exclusive product range addresses nutritional challenges faced by GLP-1 medication users across five categories:

  • GLP-1 Support Nutrient Powder with 25g protein and 24 vitamins & minerals
  • GLP-1 Support Protein featuring 30g whey protein and 5g collagen
  • GLP-1 Support Fiber providing 15g fiber per serving
  • GLP-1 Support Synbiotic for gut health
  • GLP-1 Support Multivitamins in Men's & Women's formulas

The products were developed in consultation with dietitians and the Whole Health Rx Medical Advisory Council, building upon the company's telehealth platform launched in May 2024. All supplements undergo independent third-party testing and are available exclusively at The Vitamin Shoppe stores and website.

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Positive

  • First-to-market advantage in the growing GLP-1 medication support supplement category
  • Exclusive product line strengthens competitive position
  • Builds upon existing telehealth platform expanding revenue streams
  • Doctor-approved and dietitian-formulated products enhance credibility

Negative

  • Heavy reliance on GLP-1 medication market which could be affected by regulatory changes
  • distribution through own retail channels may restrict market reach

Insights

The Vitamin Shoppe's launch of their GLP-1 Support supplement line represents a strategic market expansion into the rapidly growing GLP-1 weight management ecosystem. This product launch directly capitalizes on the explosive growth of GLP-1 medications like Ozempic and Mounjaro, positioning The Vitamin Shoppe to capture complementary revenue streams from this consumer base.

The company has identified a genuine market need, as GLP-1 medications are known to cause nutrient depletion through reduced food intake and digestive changes. By creating a specialized, targeted product line with five distinct supplement categories, The Vitamin Shoppe is establishing itself as a first-mover in the GLP-1 support supplement space.

Particularly noteworthy is the company's integrated approach, connecting this product line with their existing Whole Health Rx telehealth platform launched in 2024. This creates a comprehensive ecosystem for weight management consumers that spans from prescription access to nutritional support products.

From a competitive standpoint, The Vitamin Shoppe gains significant differentiation with this doctor-approved, dietitian-formulated product line using premium ingredients. The emphasis on exclusive retail availability through their own channels creates a valuable traffic driver to their physical and online storefronts.

While financial projections aren't provided, this launch represents a forward-thinking approach to capitalize on a burgeoning health trend with substantial growth potential for the specialty retailer.

The Vitamin Shoppe's GLP-1 Support line demonstrates excellent market timing and targeted product development in response to a significant healthcare trend. GLP-1 agonists have revolutionized weight management, with prescriptions growing exponentially since FDA approvals for weight loss.

What makes this launch particularly strategic is the focus on addressing documented clinical challenges with GLP-1 medications. Users commonly experience muscle loss, nutritional deficiencies, and digestive issues - all directly targeted by these formulations. The product line addresses real physiological needs rather than simply capitalizing on a trend.

The involvement of the company's Medical Advisory Council and registered dietitians in formulation enhances credibility in the healthcare professional community, potentially creating recommendation pathways through healthcare providers to end consumers.

From a business perspective, this supplement line creates an attractive recurring revenue opportunity. GLP-1 medication users typically remain on therapy for extended periods, potentially translating to long-term supplement usage and customer retention.

Beyond immediate revenue potential, this launch positions The Vitamin Shoppe as an authoritative voice in the GLP-1 support space. Their telehealth integration creates a uniquely holistic approach that competitors will struggle to replicate quickly, establishing a potential moat in this emerging market segment.

The dietitian formulated, doctor-approved GLP-1 Support from Whole Health Rx™ by The Vitamin Shoppe® range of supplements delivers comprehensive nutritional solutions for individuals on GLP-1 weight-loss medications

SECAUCUS, N.J., March 31, 2025 /PRNewswire/ -- The Vitamin Shoppe®, a leading omni-channel specialty retailer of nutritional products, today announced the launch of GLP-1 Support from Whole Health Rx™ by The Vitamin Shoppe®, an innovative line of dietary supplements designed to address the unique health and nutritional needs of individuals using GLP-1 medications for weight management.

Available exclusively at The Vitamin Shoppe and Super Supplements stores nationwide, as well as www.vitaminshoppe.com, this doctor-approved, dietitian-formulated supplement range provides targeted support across five essential categories: protein, fiber, probiotics, multivitamins, and a comprehensive all-in-one nutrient solution.

"With the surge in GLP-1 medication use for weight loss, we recognized a critical gap in the market for tailored nutritional support," said Muriel Gonzalez, President of The Vitamin Shoppe. "GLP-1 medications can significantly impact appetite, digestion, and nutrient absorption, making supplementation essential. Building on the expertise of The Vitamin Shoppe's Whole Health Rx telehealth platform, we developed these new GLP-1 Support products as an easy-to-understand, one-stop solution for consumers seeking a balanced and holistic approach to weight loss and nutrient supplementation."

An Expert-Led Approach to GLP-1 Supplementation

Formulated with premium, clinically studied ingredients, in close consultation with dietitians and the Whole Health Rx Medical Advisory Council, the GLP-1 Support from Whole Health Rx collection is specifically designed to address common dietary gaps and side effects associated with GLP-1 medications:

  • GLP-1 Support Nutrient Powder – A powerhouse meal replacement providing 25g of high-quality protein, 24 essential vitamins & minerals, digestive enzymes, fiber, and a full serving of Truserv® greens. This all-in-one formula helps maintain lean muscle mass, supports digestion, and replenishes key nutrients often depleted by reduced food intake.

  • GLP-1 Support Protein – Featuring 30g of whey protein, 5g of collagen for skin health (which is often impacted by weight loss), and cutting-edge, muscle-preserving ingredients like myHMB® and PeptiStrong®, this formula helps counteract muscle loss—a key concern for GLP-1 users.

  • GLP-1 Support Fiber – With 15g of fiber per serving to support digestion, this advanced blend includes antioxidant-rich Natureknit™ fruit and vegetable fiber, Inavea™ acacia fiber, and Fibersol®-2, clinically shown to enhance GLP-1 activity.

  • GLP-1 Support Synbiotic – A triple-action gut health solution, combining PreForPro® prebiotic, HOWARU® Shape probiotic, and ButyraGen® postbiotic, to optimize digestion, immune health, and Akkermansia production—a beneficial gut bacteria linked to weight management and metabolic health.

  • GLP-1 Support Multivitamins (Men's & Women's Formulas) – These advanced daily multivitamins provide a host of essential nutrients across energy, metabolism, brain, heart, and immune health. Formulated with Suntheanine® for stress support, plus ginger for occasional nausea—two common concerns among GLP-1 users.

"GLP-1 users face specific nutritional challenges and finding products tailored to these needs can be challenging," said Tabitha Daley, a Registered Dietitian nutritionist with The Vitamin Shoppe who helped formulate the GLP-1 Support from Whole Health Rx products. "Our goal was to create an accessible, science-backed system that fills essential nutrient gaps, while also helping individuals feel their best throughout their weight-loss journey by addressing nutrition-related issues that are associated with GLP-1 drugs."

Quality & Innovation You Can Trust

As part of The Vitamin Shoppe's Quality Promise, each GLP-1 Support from Whole Health Rx supplement meets or exceeds industry standards for ingredient quality, manufacturing integrity, and independent third-party testing for purity and potency.

This product launch builds upon The Vitamin Shoppe's Whole Health Rx by The Vitamin Shoppe telehealth platform, which debuted in May 2024 to provide clinician-guided prescription access to GLP-1 medications (including Ozempic®, Mounjaro®, compounded semaglutide, and compounded tirzepatide), along with testosterone replacement therapy (TRT) solutions such as KYZATREX®.

To learn more about the complete portfolio of GLP-1 weight loss solutions from Whole Health Rx by The Vitamin Shoppe, visit https://www.vitaminshoppe.com/lp/glp1-weightloss.

About The Vitamin Shoppe®

Lifelong Wellness Starts Here™. The Vitamin Shoppe®, a subsidiary of Franchise Group, Inc., is a global, omnichannel specialty retailer and wellness lifestyle Company with the mission of providing customers with the most trusted products, guidance, and services to support them on their journeys of lifelong wellness. Based in Secaucus, New Jersey, the Company offers a comprehensive assortment of nutritional solutions, including vitamins, minerals, sports nutrition, specialty supplements, herbs, homeopathic remedies, and green living products. In addition to carrying products from approximately 700 national brands, The Vitamin Shoppe offers products from its proprietary brands within its owned and wholesale channels, including: The Vitamin Shoppe®, Vthrive The Vitamin Shoppe®, BodyTech®, BodyTech® Elite, plnt®, ProBioCare®, and True Athlete®. In the U.S., the Company conducts business through over 675 company-operated retail stores under The Vitamin Shoppe and Super Supplements™ banners and via its website, www.vitaminshoppe.com. Globally, The Vitamin Shoppe serves customers in select Asia, South America, and Central America markets through local omnichannel partners.

FAQ

What products are included in The Vitamin Shoppe's new GLP-1 Support supplement line?

The line includes five products: Nutrient Powder, Protein supplement, Fiber supplement, Synbiotic formula, and gender-specific Multivitamins.

How much protein does the GLP-1 Support Nutrient Powder contain?

The GLP-1 Support Nutrient Powder contains 25g of high-quality protein along with 24 essential vitamins & minerals.

What specific benefits does the GLP-1 Support Protein supplement offer?

It provides 30g of whey protein, 5g of collagen for skin health, and muscle-preserving ingredients like myHMB® and PeptiStrong®.

Where can customers purchase The Vitamin Shoppe's GLP-1 Support supplements?

The supplements are available exclusively at The Vitamin Shoppe and Super Supplements stores nationwide and on vitaminshoppe.com.

How does The Vitamin Shoppe ensure quality in their GLP-1 Support supplement line?

Each supplement undergoes independent third-party testing for purity and potency, meeting or exceeding industry standards for ingredient quality and manufacturing integrity.
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