Vaxart Inc Stock Price, News & Analysis

Vaxart, a clinical-stage biotechnology company, will present at the Jefferies Virtual Healthcare Conference on June 4, 2021. CEO Andrei Floroiu and CSO Sean Tucker will discuss the company's innovative oral recombinant vaccines. The presentation is scheduled for 1:30 PM Eastern Time and will last until 1:55 PM. Investors can schedule virtual one-on-one meetings during the conference. Vaxart focuses on developing oral tablets for various vaccines, including those for coronavirus and norovirus, aiming to streamline vaccine administration.

Vaxart, Inc. (Nasdaq: VXRT) has initiated a Phase 1b trial assessing its oral norovirus vaccine in elderly participants aged 55 to 80. This first subject enrollment marks a significant step in addressing the lack of approved vaccines for norovirus, which causes considerable illness and deaths annually among older adults. The study aims to evaluate safety and immunogenicity, with results expected to inform future COVID-19 vaccine development. Norovirus is responsible for 56,000 to 71,000 hospitalizations and 570 to 800 deaths each year in the U.S., with a substantial economic burden of $10.5 billion.

Vaxart (Nasdaq: VXRT) has initiated a Phase 1b trial for its norovirus oral vaccine candidate, enrolling the first subject. This study aims to assess various dosing regimens' safety and immunogenicity. Norovirus causes approximately 15% of U.S. children under five to fall ill annually, resulting in a $10.5 billion economic burden. The trial design includes 30 subjects aged 18-55, divided into three cohorts, focusing on optimal booster timing. Results may also influence Vaxart's COVID-19 oral vaccine program, entering Phase 2 trials mid-year.

Vaxart (Nasdaq: VXRT) announced positive results from its Phase I COVID-19 vaccine trial, highlighting that its oral vaccine candidate, VXA-CoV2-1, induces higher CD8⁺ T-cell responses compared to the Moderna and Pfizer vaccines. The vaccine induces mucosal immunity and shows cross-reactivity against various coronaviruses.

CEO Andrei Floroiu emphasized the potential benefits of these immune responses, while Chief Scientific Officer Dr. Sean Tucker noted their importance in fighting severe infections. The study's comparative data suggests Vaxart's vaccine may offer unique advantages against evolving variants.

Vaxart, Inc. (Nasdaq: VXRT) announced its progress on three oral tablet COVID-19 vaccine candidates, advancing VXA-CoV2-1 to Phase II and two S-only constructs to Phase I/II. The company aims to start four clinical trials for its oral norovirus vaccine in 2021. As of March 31, 2021, Vaxart reported cash equivalents of $177.3 million, a rise from $126.9 million at the end of 2020. However, the company faced a net loss of $16.0 million in Q1 2021, with revenue dropping to $506,000, primarily due to reduced royalty revenue.

Vaxart (Nasdaq: VXRT) announced that its founder and chief scientific officer, Sean Tucker, Ph.D., will present at the virtual World Vaccine Congress from May 4-6, 2021. The presentation, titled Vaxart oral COVID-19 vaccine; hold the ice and the needles, focuses on the company’s innovative oral tablet vaccine designed to combat COVID-19 without refrigeration. This congress is a premier event covering the entire vaccine value chain, highlighting scientific advancements and collaborations.

Vaxart, a clinical-stage biotechnology company, announced a webinar on May 3, 2021, discussing T-cell responses in COVID-19 vaccines, featuring Dr. Mark Davis from Stanford University. This event comes amid concerns over new COVID-19 variants and aims to highlight the potential of T-cell engagement alongside antibody production.

Vaxart will present new data from its Phase I trial for its VXA-CoV2-1 vaccine, which suggests it may offer protection against emerging strains. This data could play a significant role in vaccine efficacy against variants.

Vaxart, Inc. (Nasdaq: VXRT) announced the appointment of Dr. David Wheadon to its Board of Directors, leveraging his extensive experience in global health policy and regulatory affairs. Dr. Wheadon, previously at AstraZeneca, aims to guide Vaxart as it advances its oral vaccine portfolio, including a COVID-19 candidate set for Phase 2 trials. Vaxart’s innovative tablet vaccines promise to simplify vaccination logistics, reducing the need for refrigeration and needle use. This strategic addition to the board is expected to enhance Vaxart's leadership and development capabilities.

Nearly 19 million Americans who currently refuse vaccines would consider vaccination if offered a pill option, according to a Vaxart commissioned poll. Conducted by Quadrant Strategies, the survey indicates that 70% of respondents prefer a pill over injection. The potential impact includes improving vaccination rates among underrepresented minority groups. Vaxart has completed Phase 1 of its oral COVID-19 vaccine, achieving necessary safety and immunogenicity endpoints. The findings emphasize the need for alternatives to needle injections to enhance public health efforts.