Welcome to our dedicated page for Vaxart news (Ticker: VXRT), a resource for investors and traders seeking the latest updates and insights on Vaxart stock.
Vaxart, Inc. (OTCQX: VXRT) is a clinical-stage biotechnology company developing oral recombinant vaccines delivered as pills, and its news flow reflects progress across multiple vaccine programs and corporate developments. The company regularly issues updates on its clinical trials for oral pill vaccine candidates targeting coronavirus, norovirus and influenza, as well as a therapeutic HPV vaccine candidate that it identifies as its first immune-oncology program.
Readers following Vaxart news can expect detailed reports on clinical data from its oral vaccine platform. For example, the company has announced Phase 1 results for a bivalent norovirus pill vaccine in lactating women, describing safety, tolerability and increases in norovirus-specific IgA in serum and breast milk, along with evidence of norovirus-specific IgA in infant stool. Vaxart has also highlighted data from second-generation norovirus constructs showing stronger blocking antibody responses and robust fecal IgA increases, and has presented these findings at scientific conferences such as the International Calicivirus Conference, World Vaccine Congress and IDWeek.
Vaxart’s news also covers its COVID-19 oral pill vaccine program, including enrollment and follow-up in a large Phase 2b trial funded under a Project NextGen/BARDA contract, and regulatory and funding updates such as a stop work order that delimited certain activities while maintaining support for follow-up of enrolled participants. In addition, the company has reported on an exclusive, worldwide license and collaboration agreement with Dynavax Technologies Corporation for its oral COVID-19 vaccine candidate, outlining the structure of upfront payments, an equity investment, and potential milestones and royalties.
Beyond clinical and partnership news, Vaxart issues releases on corporate actions, including stock listing changes, governance matters and capital markets events such as conference presentations and investor calls. Investors and observers can use this news feed to track the evolution of Vaxart’s oral vaccine platform, key trial readouts, collaboration milestones and changes in its trading venue and cost management initiatives.
Vaxart, Inc. (NASDAQ: VXRT) will host an investor panel on November 19, 2020, featuring key opinion leaders discussing their oral vaccine technology aimed at combating COVID-19 and Norovirus. The panel includes insights on immunity, disease prevention, and Vaxart's investigational vaccines. Management will update on their Phase 1 trial for Norovirus and provide preclinical data for their oral COVID-19 vaccine candidate, VXA-CoV2-1. The company emphasizes the potential advantages of oral vaccines over traditional injections, including ease of distribution and administration.
SOUTH SAN FRANCISCO, Calif., Nov. 16, 2020 – Vaxart, Inc. (NASDAQ: VXRT) announced participation in two upcoming virtual investor conferences. The Jefferies 2020 Virtual London Healthcare Conference will take place from November 17-19, with Vaxart's presentation scheduled for November 19 at 2:20 p.m. ET. Additionally, the Piper Sandler 32nd Annual Virtual Healthcare Conference is set for December 1-3. Vaxart focuses on developing oral vaccines for various infectious diseases, including COVID-19. For further details, visit their investors section.
Vaxart announced the completion of enrollment in its Phase 1 trial for VXA-CoV2-1, an oral COVID-19 vaccine candidate. The trial data show significant viral load reduction and strong antibody responses in a hamster model. The company reported a net loss of $8.1 million for Q3 2020, an increase from $5.3 million in Q3 2019, primarily due to higher operating expenses. Revenue dropped to $265,000, down from $454,000 in Q3 2019, attributed mainly to reduced contract activities with Janssen. Vaxart ended Q3 with $133.4 million in cash, boosted by a recent stock issuance.
Vaxart, Inc. (NASDAQ: VXRT) reported promising results from its Hamster Challenge Study for its oral COVID-19 vaccine candidate. The study indicated a significant reduction in lung viral load by 4-5 logs in vaccinated hamsters versus unvaccinated ones. Additionally, antibody response was strong, with serum IgG levels exceeding 10,000. The oral vaccine performed comparably to intranasal options in preventing weight loss and lung complications. CEO Andrei Floroiu emphasized the convenience of their room-temperature-stable oral vaccine, which could be a practical alternative to injectable vaccines.
Vaxart (NASDAQ: VXRT) released promising results from its Hamster Challenge Study, indicating that all hamsters receiving two oral doses of its COVID-19 vaccine candidate did not experience systemic weight loss, a key protective measure. Dr. Sean Tucker highlighted that these results validate the vaccine's potential against COVID-19 as the company prepares for human clinical trials. The study showed that unvaccinated hamsters lost significant weight and exhibited lung issues, whereas vaccinated ones maintained or gained weight (p<0.001). Vaxart aims to provide a convenient oral vaccine solution.
Vaxart, a clinical-stage biotechnology firm, announced the dosing of the first subject in its Phase 1 study for VXA-CoV2-1, an oral COVID-19 vaccine candidate. The open-label trial aims to assess safety and immunogenicity in 48 healthy adults. Preclinical data suggest the vaccine can trigger significant systemic and mucosal immune responses. Enrollment is expected to finish by early November 2020, with initial clinical data available shortly thereafter. Vaxart's oral tablet vaccine may simplify distribution and administration compared to traditional injectable vaccines.
Vaxart, a clinical-stage biotechnology company, announced the FDA's approval for its Investigational New Drug (IND) application for a Phase 1 trial of its oral COVID-19 vaccine. Recruitment for the trial is set to start this month, targeting healthy adults aged 18 to 55. The primary focus is on safety and reactogenicity, while secondary aims include measuring immune response duration. Additionally, Vaxart expects results from hamster and non-human primate challenge studies this October. The oral vaccine platform offers advantages like easier distribution due to stability at room temperature.
Vaxart, Inc. (NASDAQ: VXRT) announced the appointment of Karen J. Wilson to its Board of Directors and as chair of the Audit Committee. With over 30 years in finance within the life sciences sector, Wilson's experience is expected to bolster Vaxart's growth as they advance their oral COVID-19 vaccine candidate. CEO Andrei Floroiu highlighted her expertise as a significant asset for the company, which is focused on developing oral vaccines for various infectious diseases. Vaxart’s innovative tablet vaccines aim to simplify distribution and enhance pandemic response.
Vaxart, Inc. (NASDAQ: VXRT) recently announced a study in the Journal of Infectious Diseases highlighting that norovirus gastroenteritis costs the U.S. approximately $10.6 billion annually, primarily due to sporadic cases rather than publicized outbreaks. Conducted by PHICOR, the study suggests over 50% of these costs occur during winter months, emphasizing the need for timely preventative measures. Furthermore, productivity losses account for 89% of overall costs, underscoring the substantial economic burden. Vaxart supports the research to advance its oral norovirus vaccine program.
Vaxart, Inc. (NASDAQ: VXRT) announced it raised approximately $90 million through its At-the-Market facility, selling 11.2 million shares at $7.98 each. The funds will support clinical development and product manufacturing. SVB Leerink and B. Riley FBR are involved as sales agents. The offering was made under an effective shelf registration statement filed with the SEC. Vaxart focuses on developing oral vaccines for infectious diseases, including COVID-19, with the goal of achieving easier distribution compared to injectable vaccines.