STOCK TITAN

Wave Life Scienc Stock Price, News & Analysis

WVE Nasdaq

Welcome to our dedicated page for Wave Life Scienc news (Ticker: WVE), a resource for investors and traders seeking the latest updates and insights on Wave Life Scienc stock.

Wave Life Sciences Ltd. (NASDAQ: WVE) is a clinical-stage biotechnology leader advancing RNA medicines through its proprietary PRISM platform. This page provides investors and researchers with timely updates on the company's stereopure oligonucleotide therapies targeting genetic disorders.

Access the latest press releases covering clinical trial progress, regulatory milestones, and scientific advancements. Our curated collection includes updates across WVE's pipeline, including programs for Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency, and neurological conditions.

Key news categories include:
• Clinical development updates
• Strategic research collaborations
• Regulatory pathway announcements
• Scientific publication highlights

Bookmark this page for direct access to primary source materials about WVE's innovative approach to RNA editing and antisense technologies. Monitor critical developments in precision genetic medicine through verified company communications.

Rhea-AI Summary

Wave Life Sciences (Nasdaq: WVE) has announced the pricing of its upsized public offering of ordinary shares and pre-funded warrants, aiming to raise approximately $200 million in gross proceeds. The offering includes 23,125,001 ordinary shares at $8.00 per share and pre-funded warrants to purchase up to 1,875,023 ordinary shares at $7.9999 per warrant. The company has also granted underwriters a 30-day option to purchase up to an additional 3,750,000 ordinary shares. The offering is expected to close around September 27, 2024. J.P. Morgan and Leerink Partners are acting as joint book-running managers, with Truist Securities and Mizuho as book-runners. The offering is being made through a prospectus and related supplement, with details available on the SEC's website.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-10.99%
Tags
-
Rhea-AI Summary

Wave Life Sciences (Nasdaq: WVE) has announced a proposed public offering of $175 million in ordinary shares and pre-funded warrants. The biotechnology company, focused on RNA medicines, intends to grant underwriters a 30-day option to purchase additional ordinary shares up to 15% of the total offering. J.P. Morgan and Leerink Partners are acting as joint book-running managers, with Truist Securities and Mizuho as book-runners.

The offering is subject to market conditions and will be made through a prospectus and related supplement. A preliminary prospectus supplement and accompanying base prospectus will be filed with the SEC and available on their website. The final terms will be disclosed in a final prospectus supplement.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
10.01%
Tags
-
Rhea-AI Summary

Wave Life Sciences announced positive interim data from the FORWARD-53 clinical trial evaluating WVE-N531 in boys with Duchenne Muscular Dystrophy (DMD) amenable to exon 53 skipping. Key findings include:

- Mean muscle content-adjusted dystrophin expression of 9.0% and unadjusted dystrophin of 5.5%
- Meaningful improvement in serum biomarkers for muscle health
- Skeletal muscle concentrations of ~41,000 ng/g with 61-day tissue half-life
- WVE-N531 was safe and well-tolerated with only mild treatment-related adverse events

The company expects feedback on a pathway to accelerated approval and complete 48-week data in Q1 2025. Wave Life Sciences is advancing a broader DMD pipeline targeting up to 40% of boys with DMD.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
53.37%
Tags
Rhea-AI Summary

Wave Life Sciences (Nasdaq: WVE) has received FDA Rare Pediatric Disease Designation for WVE-N531, a treatment for Duchenne muscular dystrophy (DMD) patients amenable to exon 53 skipping. The company expects to deliver data from the potentially registrational FORWARD-53 trial, including dystrophin protein expression, in Q3 2024.

In a previous Part A study, WVE-N531 achieved 53% exon skipping and muscle tissue concentrations 20-30 times higher than those reported by technologies using muscle delivery conjugates. The treatment also demonstrated distribution to myogenic stem cells, a unique feature among exon skipping therapies. Preclinical data showed potential for cardiac and respiratory benefits.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.74%
Tags
-
Rhea-AI Summary

Wave Life Sciences (Nasdaq: WVE) reported Q2 2024 financial results and provided a business update. Key highlights include:

1. Successful clinical translation of RNA medicines platform in HD patients with WVE-003, showing statistically significant mHTT reductions up to 46%.

2. Dystrophin data expected in Q3 2024 from FORWARD-53 trial of WVE-N531 for DMD.

3. Dosing initiated in RestorAATion-2 trial of WVE-006 for AATD; proof-of-mechanism data expected in Q4 2024.

4. New preclinical data on WVE-007 for obesity expected at R&D Day in Fall 2024.

5. Q2 2024 revenue: $19.7 million; net loss: $32.9 million.

6. Cash position: $154.0 million as of June 30, 2024, expected to fund operations into Q4 2025.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-4.01%
Tags
-
Rhea-AI Summary

Wave Life Sciences (Nasdaq: WVE), a clinical-stage biotechnology company focusing on RNA medicines, has announced its upcoming second quarter 2024 financial results release. The company will host a live webcast and conference call on Thursday, August 8, 2024, at 8:30 a.m. ET to discuss the results and provide business updates.

Investors and interested parties can access the webcast through the 'Investor Events' section of the company's website. Analysts wishing to participate in the Q&A session can join via a provided audio conferencing link. An archived version of the webcast will be available on the company's website following the live event.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-6.81%
Tags
Rhea-AI Summary

Wave Life Sciences announced positive results from their Phase 1b/2a SELECT-HD trial for WVE-003, a therapeutic for Huntington's disease (HD). The trial showed a statistically significant 46% reduction in mutant huntingtin (mHTT) protein in the cerebrospinal fluid compared to placebo, while preserving wild-type huntingtin (wtHTT) protein. The drug was generally safe and well-tolerated. These results validate Wave's RNA medicines platform and support potential accelerated approval discussions with regulators. Wave plans to continue developing WVE-003 and other therapies targeting HD and other conditions, with anticipated data releases in 2024 and 2025.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-8.45%
Tags
-
Rhea-AI Summary

Wave Life Sciences announced upcoming presentations at two significant conferences in June 2024. At the Obesity & Weight Loss Drug Development Summit, they will discuss their INHBE program, targeting fat burning and muscle preservation. At the RNA Editing Summit, they will present their RNA editing capabilities for mRNA correction, highlighting their WVE-006 program for Alpha-1 antitrypsin deficiency. The company aims to demonstrate the potential of their RNA medicines in treating both rare and common diseases.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
3.06%
Tags
conferences
-
Rhea-AI Summary

Wave Life Sciences, a clinical-stage biotech company, will present at the 2024 Jefferies Global Healthcare Conference. The event is scheduled for June 6, 2024, at 7:30 a.m. ET, and will feature a presentation by Paul Bolno, the CEO. A live webcast will be accessible through the Investor Relations page on the company's website, with a replay available for a time. This event provides insight into the company's progress in RNA medicines aimed at transforming human health.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
2.83%
Tags
conferences
Rhea-AI Summary

Wave Life Sciences reported its first quarter 2024 financial results and provided updates on its innovative RNA medicines pipeline and collaborations. The company remains on track for key data sets, including proof-of-mechanism data in AATD patients, INHBE program for obesity, GSK collaboration programs, allele-selective HD program, and registrational FORWARD-53 trial in DMD. Wave has cash and cash equivalents of $181 million and additional $12 million earned under GSK collaboration. The company is well-positioned for future growth and leadership in RNA medicines.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-1.54%
Tags

FAQ

What is the current stock price of Wave Life Scienc (WVE)?

The current stock price of Wave Life Scienc (WVE) is $7.7 as of July 11, 2025.

What is the market cap of Wave Life Scienc (WVE)?

The market cap of Wave Life Scienc (WVE) is approximately 1.1B.
Wave Life Scienc

Nasdaq:WVE

WVE Rankings

WVE Stock Data

1.08B
130.28M
16.53%
83.51%
5.97%
Biotechnology
Pharmaceutical Preparations
Link
Singapore
SINGAPORE