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Wave Life Scienc Financials

WVE
FY2025 annual
Revenue $42.7M -60.5% YoY
Net Income -$204.4M -110.7% YoY
EPS (Diluted) -$1.21 -72.9% YoY
Free Cash Flow -$188.2M -23.9% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Wave Life Scienc (WVE) reported $42.7M in revenue for fiscal year 2025, down 60.5% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 13 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI WVE FY2025

Wave Life Sciences runs a cash-funded development model, where external capital rather than revenue pays for a rising R&D program.

FY2025's cash balance reached $602.1M even as operating cash burn deepened to -$187.5M. With financing inflows of $488.2M and liabilities down to $112.3M, the stronger liquidity came from fresh capital rather than operating self-sufficiency.

R&D intensity still defines the business: spending of $182.8M was more than four times FY2025 revenue of $42.7M. With capex at only $718K and a 6.5x current ratio, this looks like an asset-light research engine with comfortable near-term liquidity.

Another key pattern is episodic revenue: after topping $100M for two straight years, it fell to $42.7M in the latest year. Because operating costs kept rising, the operating loss widened to -$215.4M and shares outstanding reached 187.7M, showing a growing fixed cost base that still depends on outside funding.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 49 / 100
Financial Health Score 49/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Wave Life Scienc's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
66
Dilution
28
R&D Intensity
92
Revenue Progress
10
Burn Trend
3
Balance Sheet
96
Altman Z-Score Grey Zone
2.59

Wave Life Scienc scores 2.59, placing it in the grey zone between 1.81 and 2.99. The score is driven primarily by a large market capitalization ($1.0B) relative to total liabilities ($112.3M). This signals moderate financial risk that warrants monitoring.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/7

Wave Life Scienc passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Wave Life Scienc reported a net loss of $204.4M while operations used $187.5M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$42.7M
YoY-60.5%
5Y CAGR+16.3%
10Y CAGR+75.7%

Wave Life Scienc generated $42.7M in revenue in fiscal year 2025. This represents a decrease of 60.5% from the prior year.

EBITDA
-$211.9M
YoY-99.0%

Wave Life Scienc's EBITDA was -$211.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 99.0% from the prior year.

Net Income
-$204.4M
YoY-110.7%

Wave Life Scienc reported -$204.4M in net income in fiscal year 2025. This represents a decrease of 110.7% from the prior year.

EPS (Diluted)
-$1.21
YoY-72.9%

Wave Life Scienc earned -$1.21 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 72.9% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$188.2M
YoY-23.9%

Wave Life Scienc recorded an outflow of $188.2M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 23.9% from the prior year.

Cash & Debt
$602.1M
YoY+99.3%
5Y CAGR+26.7%
10Y CAGR+14.1%

Wave Life Scienc held $602.1M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
188M
YoY+22.6%

Wave Life Scienc had 188M shares outstanding in fiscal year 2025. This represents an increase of 22.6% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-39.4%
YoY+6.9pp

Wave Life Scienc's ROE was -39.4% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 6.9 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$182.8M
YoY+14.5%
5Y CAGR+6.9%
10Y CAGR+35.0%

Wave Life Scienc invested $182.8M in research and development in fiscal year 2025. This represents an increase of 14.5% from the prior year.

Capital Expenditures
$718K
YoY-23.5%
5Y CAGR-11.7%
10Y CAGR-9.1%

Wave Life Scienc invested $718K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 23.5% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

WVE Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

WVE annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13
RevenueN/A$42.7M-60.5%$108.3M-4.4%$113.3M+3005.1%$3.6M-91.1%$41.0M+104.0%$20.1M+25.6%$16.0M+10.9%$14.4M+289.1%$3.7M+149.4%$1.5M+877.0%$152KN/AN/A
R&D ExpensesN/A$182.8M+14.5%$159.7M+22.8%$130.0M+12.2%$115.9M-4.9%$121.9M-6.9%$130.9M-25.4%$175.4M+30.5%$134.4M+69.5%$79.3M+94.3%$40.8M+350.7%$9.1M+278.2%$2.4M+24.7%$1.9M
SG&A ExpensesN/A$75.3M+27.6%$59.0M+15.1%$51.3M+1.5%$50.5M+9.6%$46.1M+8.5%$42.5M-13.0%$48.9M+23.7%$39.5M+46.5%$27.0M+68.7%$16.0M+53.9%$10.4M+246.5%$3.0M+81.3%$1.7M
Operating IncomeN/A-$215.4M-95.1%-$110.4M-62.4%-$68.0M+58.2%-$162.7M-28.1%-$127.0M+17.2%-$153.4M+26.4%-$208.3M-30.6%-$159.5M-55.8%-$102.4M-83.8%-$55.7M-188.7%-$19.3M-257.8%-$5.4M-50.9%-$3.6M
Interest ExpenseN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A$86K+816.7%-$12K+89.2%-$111K
Income TaxN/A$0$0+100.0%-$677K-199.4%$681K+433.8%-$204K+75.7%-$841K$0-100.0%$69K-91.8%$842K+74.7%$482K+995.5%$44K-47.6%$84K+125.5%-$330K
Net IncomeN/A-$204.4M-110.7%-$97.0M-68.7%-$57.5M+64.5%-$161.8M-32.4%-$122.2M+18.5%-$149.9M+22.6%-$193.6M-32.0%-$146.7M-43.8%-$102.0M-83.2%-$55.7M-189.9%-$19.2M-267.2%-$5.2M-57.6%-$3.3M
EPS (Diluted)-$1.21-72.9%-$0.70-29.6%-$0.54+73.7%-$2.05-$2.36N/AN/AN/AN/AN/AN/AN/AN/A

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

WVE Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

WVE annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13
Total Assets$638.5M+81.3%$352.2M+28.1%$274.9M+87.8%$146.4M-29.3%$207.0M-25.9%$279.2M-1.8%$284.3M-4.0%$295.9M+62.7%$181.8M+10.3%$164.8M-0.4%$165.4M+5530.5%$2.9MN/A
Current Assets$614.8M+91.9%$320.4M+36.1%$235.4M+138.9%$98.5M-39.4%$162.6M-29.3%$230.0M+24.0%$185.5M-8.3%$202.3M+34.4%$150.5M-1.0%$152.0M-5.8%$161.4M+10753.0%$1.5MN/A
Cash & Equivalents$602.1M+99.3%$302.1M+50.8%$200.4M+126.4%$88.5M-41.2%$150.6M-18.4%$184.5M+25.4%$147.2M-15.8%$174.8M+22.7%$142.5M-5.2%$150.3M-6.8%$161.2M+15283.6%$1.0M+138.7%$439K
Accounts Receivable$1.3M-10.3%$1.4M-93.3%$21.1MN/AN/A$30.0M+50.0%$20.0M+100.0%$10.0M+900.0%$1.0MN/AN/A$200KN/A
Total Liabilities$112.3M-16.7%$134.8M-40.7%$227.4M+23.9%$183.6M+10.2%$166.6M-11.6%$188.6M-11.3%$212.6M-1.0%$214.7M+524.9%$34.4M+55.7%$22.1M+443.8%$4.1M+345.6%$911KN/A
Current Liabilities$95.1M-14.3%$111.0M-40.5%$186.4M+160.7%$71.5M+11.4%$64.2M-47.0%$121.0M+2.4%$118.2M-9.1%$130.0M+614.9%$18.2M+49.7%$12.2M+218.4%$3.8M+332.9%$882KN/A
Total Equity$518.4M+147.4%$209.5M+428.7%$39.6M+187.9%-$45.1M-238.8%$32.5M-60.7%$82.8M+29.9%$63.7M-13.1%$73.3M-47.5%$139.6M+3.7%$134.6M-12.3%$153.5M+7472.3%$2.0M+126.1%-$7.8M
Retained Earnings-$1.3B-18.2%-$1.1B-9.5%-$1.0B-5.9%-$967.3M-20.1%-$805.5M-17.9%-$683.3M-28.1%-$533.4M-57.0%-$339.7M-76.3%-$192.7M-113.0%-$90.5M-157.9%-$35.1M-120.9%-$15.9MN/A

Not reported in any period shown, so not listed: Inventory, Goodwill, Long-Term Debt.

WVE Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

WVE annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13
Operating Cash Flow-$191.6M-$187.5M-24.1%-$151.0M-677.2%-$19.4M+84.8%-$127.8M-43.6%-$89.0M+23.3%-$116.0M+38.4%-$188.2M-723.3%-$22.9M+72.7%-$83.7M-162.1%-$31.9M-154.8%-$12.5M-183.0%-$4.4M-24.6%-$3.6M
Capital Expenditures$1.6M$718K-23.5%$938K-15.9%$1.1M-18.1%$1.4M+143.0%$560K-58.1%$1.3M-65.8%$3.9M-60.6%$9.9M-47.4%$18.9M+239.3%$5.6M+199.8%$1.9M+214.7%$590K+1155.3%$47K
Free Cash Flow-$193.1M-$188.2M-23.9%-$152.0M-639.6%-$20.5M+84.1%-$129.1M-44.2%-$89.6M+23.7%-$117.3M+38.9%-$192.1M-485.8%-$32.8M+68.0%-$102.6M-173.5%-$37.5M-160.7%-$14.4M-186.8%-$5.0M-39.4%-$3.6M
Investing Cash Flow-$124.1M-$718K+23.5%-$938K+15.9%-$1.1M+11.2%-$1.3M-124.1%-$560K+58.1%-$1.3M+65.8%-$3.9M+60.6%-$9.9M+47.4%-$18.9M-239.5%-$5.6MN/AN/AN/A
Financing Cash Flow$475.2M$488.2M+92.3%$253.9M+91.6%$132.5M+97.3%$67.2M+20.3%$55.8M-63.9%$154.5M-6.0%$164.4M+152.6%$65.1M-31.0%$94.4M+224.1%$29.1MN/AN/AN/A

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

WVE Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

WVE annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13
Operating Margin-504.1%-101.9%-60.0%-4459.3%-310.1%-763.9%-1303.4%-1106.7%-2764.3%-3752.2%-12696.0%N/AN/A
Net Margin-478.3%-89.6%-38.8pp-50.8%-4434.7%-298.4%-746.7%-1211.5%-1017.4%-2753.2%-3748.1%-12631.6%N/AN/A
Return on Equity-39.4%+6.9pp-46.3%+98.8pp-145.1%N/A-376.2%-195.1pp-181.1%+122.7pp-303.8%-103.9pp-199.9%-126.9pp-73.0%-31.7pp-41.3%-28.8pp-12.5%+245.5pp-258.0%N/A
Return on Assets-32.0%-4.5pp-27.5%-6.6pp-20.9%+89.6pp-110.5%-51.5pp-59.1%-5.4pp-53.7%+14.4pp-68.1%-18.6pp-49.5%+6.5pp-56.1%-22.3pp-33.8%-22.2pp-11.6%+166.4pp-178.0%N/A
Current Ratio6.47+3.6x2.89+1.6x1.26-0.1x1.38-1.2x2.53+0.6x1.90+0.3x1.570.0x1.56-6.7x8.27-4.2x12.50-29.8x42.27+40.6x1.69N/A
Debt-to-Equity0.22-0.4x0.64-5.1x5.74N/A5.13+2.8x2.28-1.1x3.34+0.4x2.93+2.7x0.25+0.1x0.16+0.1x0.03-0.4x0.45N/A
FCF Margin-440.5%-140.3%-18.1%-3539.1%-218.6%-584.4%-1202.2%-227.6%-2768.8%-2524.7%-9463.2%N/AN/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Wave Life Scienc's annual revenue?

Wave Life Scienc (WVE) reported $42.7M in total revenue for fiscal year 2025. This represents a -60.5% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Wave Life Scienc's revenue growing?

Wave Life Scienc (WVE) revenue declined by 60.5% year-over-year, from $108.3M to $42.7M in fiscal year 2025.

Is Wave Life Scienc profitable?

No, Wave Life Scienc (WVE) reported a net income of -$204.4M in fiscal year 2025.

Wave Life Scienc (WVE) reported diluted earnings per share of -$1.21 for fiscal year 2025. This represents a -72.9% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Wave Life Scienc (WVE) had EBITDA of -$211.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Wave Life Scienc (WVE) has a return on equity of -39.4% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Wave Life Scienc (WVE) recorded an outflow of $188.2M in free cash flow during fiscal year 2025. This represents a -23.9% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Wave Life Scienc (WVE) recorded an outflow of $187.5M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Wave Life Scienc (WVE) had $638.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Wave Life Scienc (WVE) invested $718K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Wave Life Scienc (WVE) invested $182.8M in research and development during fiscal year 2025.

Wave Life Scienc (WVE) had 188M shares outstanding as of fiscal year 2025.

Wave Life Scienc (WVE) had a current ratio of 6.47 as of fiscal year 2025, which is generally considered healthy.

Wave Life Scienc (WVE) had a debt-to-equity ratio of 0.22 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Wave Life Scienc (WVE) had a return on assets of -32.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Wave Life Scienc (WVE) had $602.1M in cash against an annual operating cash burn of $187.5M. This gives an estimated cash runway of approximately 39 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Wave Life Scienc (WVE) has an Altman Z-Score of 2.59, placing it in the Grey Zone (moderate risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Wave Life Scienc (WVE) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Wave Life Scienc (WVE) reported a net loss of $204.4M while operations used $187.5M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Wave Life Scienc (WVE) scores 49 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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