Welcome to our dedicated page for Exicure news (Ticker: XCUR), a resource for investors and traders seeking the latest updates and insights on Exicure stock.
Exicure, Inc. develops clinical-stage biotechnology programs for hematologic diseases, led by burixafor (GPC-100), a highly selective small-molecule CXCR4 antagonist. Company updates center on burixafor's role in hematopoietic stem cell mobilization for multiple myeloma transplant settings, sickle cell disease, cell and gene therapy support, and acute myeloid leukemia chemosensitization.
Recurring news also covers clinical data presentations and publications, collaborations for combination approaches, financial results, liquidity disclosures, and research spending following Exicure's acquisition of GPCR Therapeutics USA. Earlier company context includes its historical focus on nucleic acid therapies and restructuring before the current hematology-focused pipeline.
Exicure, Inc. (NASDAQ: XCUR) will host a virtual R&D Day on July 15, 2021, highlighting its neuroscience pipeline, particularly XCUR-FXN for Friedreich's Ataxia (FA). This program targets the disease's molecular cause and is on track for IND filing in late Q4 2021. The event will also cover advancements in therapies for SCN9A-related neuropathic pain and CLN3 Batten Disease. CEO Dr. David Giljohann emphasizes the potential of their SNA platform to address neurological disorders with promising data that may benefit patients.
Exicure, Inc. (NASDAQ: XCUR) announced that CEO David Giljohann will present at the Ladenburg Thalmann 2021 Healthcare Conference on July 13, 2021, from 1:00-1:25 PM in Track One. The panel discussion will be webcast, with replays available for 30 days on Exicure's website. The company focuses on gene regulatory and immunotherapeutic drugs utilizing its proprietary Spherical Nucleic Acid (SNA™) technology, aimed at treating neurological, immuno-oncologic, and inflammatory diseases. Exicure is developing XCUR-FXN for Friedreich’s ataxia and cavrotolimod for advanced solid tumors.
Exicure, Inc. (NASDAQ: XCUR) has announced CEO David Giljohann's participation in two upcoming conferences. The BIO Digital 2021 conference will feature a corporate update presentation on June 10, 2021, available for on-demand viewing. The BMO Biopharma Day will include a rare disease panel on June 22, 2021, streamed live at 10:30 AM ET. Exicure focuses on developing innovative therapeutics leveraging its Spherical Nucleic Acid technology, targeting conditions such as Friedreich’s ataxia and advanced solid tumors.
Exicure, Inc. (NASDAQ: XCUR) has appointed Brian C. Bock as its new Chief Financial Officer, effective immediately. Bock brings over 20 years of experience in life science investment banking and healthcare strategy, previously serving as Managing Director at Lincoln International. His expertise is expected to enhance Exicure’s business strategy and valuation. The company granted Bock an inducement stock option for 600,000 shares at an exercise price of $1.54, vesting over four years. Exicure focuses on developing therapies using its proprietary Spherical Nucleic Acid technology for various diseases.
Exicure, Inc. (NASDAQ: XCUR) reported Q1 2021 results, highlighting significant advancements in clinical programs and board expansion. The FDA granted Fast Track and Orphan Drug designations for cavrotolimod (AST-008) aimed at treating advanced Merkel cell carcinoma and squamous cell carcinoma. The company is on track to submit an IND for XCUR-FXN for Friedreich's Ataxia by year-end 2021. Financially, the company reported a net loss of $12.5 million, up from a $1.2 million net income year-over-year, while cash reserves decreased to $67.4 million.
Exicure, Inc. (NASDAQ: XCUR) reported that Northwestern University researchers successfully utilized its gold-nanoparticle SNA technology in a first-in-human trial targeting glioblastoma (GBM). The phase 0 trial showed that intravenously administered siRNA-based SNAs can safely cross the blood-brain barrier and target the oncogene Bcl2L12. These findings, published in Science Translational Medicine, mark a significant milestone for Exicure’s technology in treating GBM. The company also plans to file an IND for Friedreich's ataxia by the end of 2021.
Exicure, Inc. (NASDAQ:XCUR) reported impressive financial results for 2020, achieving $16.6 million in revenue, up from $1.3 million in 2019, primarily due to a collaboration with AbbVie. The net loss reduced to $24.7 million from $26.3 million year-over-year. Key advancements included the initiation of IND-enabling studies for XCUR-FXN targeting Friedreich’s ataxia and multiple FDA designations for cavrotolimod (AST-008), enhancing its oncology pipeline. Despite COVID-19 related delays, Exicure expects sufficient cash runway for the next 12 months to support ongoing trials.
Exicure, Inc. (NASDAQ: XCUR) has announced the addition of Elizabeth Garofalo, M.D. and Andrew Sassine to its Board of Directors during a pivotal time for the company. The appointments are expected to enhance Exicure's development of its investigational drugs, cavrotolimod and XCUR-FXN. Garofalo brings over 25 years of clinical development experience, while Sassine contributes extensive financial expertise. Additionally, David Walt, Ph.D. will not seek re-election at the upcoming Annual Meeting. Exicure focuses on innovative therapies utilizing its proprietary Spherical Nucleic Acid technology.
Exicure, Inc. (NASDAQ: XCUR) announced that the FDA has granted Orphan Drug Designation for its candidate cavrotolimod (AST-008) targeting Merkel cell carcinoma (MCC). This designation is a significant step towards addressing unmet medical needs for MCC patients. Exicure previously received Fast Track designations for cavrotolimod for MCC and cutaneous squamous cell carcinoma (CSCC). Cavrotolimod is currently in Phase 1b/2 clinical trials, showing promising anti-tumor activity with no serious adverse events reported thus far.
Exicure, Inc. (Nasdaq: XCUR) announced that CEO David Giljohann will present at the 2021 H.C. Wainwright Global Life Sciences Conference on March 9-10, 2021. The presentation will be available for registered attendees to view on-demand starting March 9, 2021, at 7:00 AM EST, and it will be archived for 90 days. Exicure is a biotechnology firm focusing on gene regulatory therapies using its proprietary Spherical Nucleic Acid (SNA) technology, currently in preclinical development for Friedreich’s ataxia and advancing in clinical trials for solid tumors.