Xencor Stock Price, News & Analysis

Xencor, Inc. (NASDAQ: XNCR) has presented new data on its preclinical-stage IL-18 and LAG3-targeted IL-15 cytokine programs at the AACR Annual Meeting 2022. The company introduced a decoy-resistant IL18-Fc fusion protein and a LAG-3 targeted IL15/IL15Rα-Fc fusion protein aimed at preferential TIL expansion. Xencor plans to submit an investigational new drug application for XmAb662 later this year, a promising IL12-Fc cytokine with observed anti-tumor activity. These developments aim to enhance cytokine therapeutics' efficacy while reducing systemic toxicity.

Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company, announced it will present preclinical data on two new XmAb® cytokine programs at the AACR Annual Meeting in New Orleans from April 8-13, 2022. The data includes a decoy-resistant IL18-Fc fusion protein and a LAG-3 targeted IL15/IL15α-Fc fusion protein. The presentations are scheduled for April 11 and April 12, highlighting their innovative approaches to enhance immune responses in cancer treatment. Xencor's XmAb technology enables the creation of long-acting therapeutic candidates for improved patient outcomes.

Xencor, a clinical-stage biopharmaceutical company, reported its financial results for Q4 and FY 2021, highlighting significant advancements in its drug portfolio. The company initiated Phase 2 trials for vudalimab in prostate cancer and established a collaboration with Janssen. Revenues surged to $154 million in Q4, compared to $42 million in Q4 2020, while full-year revenues reached $275 million, up from $123 million. Net income for 2021 was $82.6 million, a turnaround from a net loss of $69.3 million in 2020. Xencor expects to maintain cash reserves of $500-$550 million by the end of 2022.

Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company, announced it will provide a corporate update and report financial results for Q4 and full year 2021 after market close on February 23, 2022. Management will host a conference call at 4:30 p.m. ET to discuss the updates. Xencor is developing engineered monoclonal antibodies and cytokines to treat cancer and autoimmune diseases, with 22 candidates currently in clinical development.

Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company focused on engineered monoclonal antibodies and cytokines for cancer and autoimmune diseases, will participate in two virtual investor conferences. The first is the Guggenheim Healthcare Talks | 2022 Oncology Conference on February 9, 2022, at 2:00 p.m. EST. The second is the 11th Annual SVB Leerink Global Healthcare Conference on February 16, 2022, at 3:40 p.m. EST. Live webcasts will be accessible on Xencor's website, with replays available for 30 days.

Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company, announced its corporate priorities for 2022, focusing on advancing bispecific antibody and engineered cytokine programs for cancer and autoimmune diseases. Key projects include vudalimab and plamotamab, with planned Phase 2 studies in various cancers. Xencor reported a cash position of approximately $660 million, sufficient to fund operations through 2025. The company anticipates new clinical data that may enhance its portfolio, which includes 22 candidates in development, leveraging its XmAb technology.

Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company focused on developing engineered monoclonal antibodies and cytokines for cancer and autoimmune diseases, will participate in a pre-recorded fireside chat at the H.C. Wainwright Bioconnect Virtual Conference.

The recording will be accessible starting January 10, 2022, at 4:00 a.m. PT under the 'Events & Presentations' section on the company’s website for a duration of at least 30 days.

Xencor currently has 22 candidates in clinical development utilizing its XmAb® technology.

Xencor, Inc. (NASDAQ:XNCR) announced updated data from its Phase 1 study of plamotamab, a bispecific antibody targeting B-cell non-Hodgkin lymphoma. Results will be presented at the ASH Annual Meeting. The drug showed encouraging clinical activity, with a recommended Phase 2 dose established at 50 mg every two weeks. The study demonstrated a 51% objective response rate, with 100% in patients with follicular lymphoma. A collaboration with Janssen aims to advance plamotamab development. The treatment was generally well tolerated, with manageable adverse events.

Xencor has granted Zenas BioPharma exclusive rights to develop and commercialize the investigational antibody obexelimab, aimed at treating autoimmune diseases. This agreement includes an upfront payment in the form of additional equity, with Xencor eligible for up to $480 million in milestone payments and royalties on future sales. Obexelimab is a bifunctional antibody with a unique mechanism that inhibits B-cell functions, demonstrating promising early clinical results.